Polymorphism of β2-microglobulin amyloid fibrils manifested by ultrasonication-enhanced fibril formation in trifluoroethanol

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22827-22837

  Chatani, Eri ^a,b   Yagi, Hisashi ^b   Naiki, Hironobu ^c   Goto, Yuji ^b  

^a KOBE UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF FUKUI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 ,2 ,2-TRIFLUOROETHANOL; AMYLOID DISEASE; AMYLOID FIBRIL; AMYLOID STRUCTURES; CONCENTRATION-DEPENDENT; ENHANCING EFFECT; FIBRIL FORMATION; FOURIER TRANSFORM INFRARED ABSORPTION SPECTRUM; HYDROPHOBIC INTERACTIONS; HYDROPHOBIC RESIDUES; MOLECULAR BASIS; MOLECULAR MECHANISM; NEEDLE-LIKE; POLYMORPHIC PROPERTIES; POLYMORPHIC STRUCTURE; PROTEIN SEQUENCES; THIOFLAVIN T; TRIFLUOROETHANOL; TRYPTOPHAN FLUORESCENCE; ULTRA-SONICATION;

AMINO ACIDS; DIALYSIS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GLYCOPROTEINS; HYDROPHOBICITY; IONIC STRENGTH; NUCLEATION; POLYMORPHISM;

ETHANOL;

8 ANILINO 1 NAPHTHALENESULFONIC ACID; AMYLOID; AMYLOID BETA PROTEIN; BETA 2 MICROGLOBULIN; TRIFLUOROETHANOL; TRYPTOPHAN;

AMINO ACID SEQUENCE; ARTICLE; CONCENTRATION RESPONSE; FIBER; HUMAN; HYDROPHOBICITY; INFRARED SPECTROSCOPY; IONIC STRENGTH; MOLECULAR MECHANICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN POLYMORPHISM; PROTEIN PURIFICATION; PROTEIN STRUCTURE;

AMYLOIDOSIS; BETA 2-MICROGLOBULIN; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROSCOPY, ELECTRON, TRANSMISSION; PHENOTYPE; POLYMORPHISM, GENETIC; PROTEIN FOLDING; PROTEOSTASIS DEFICIENCIES; TRIFLUOROACETIC ACID; ULTRASONICS; WATER;

EID: 84863319706     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.333310     Document Type: Article

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