Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 23216-23226

  Sundvall, Maria ^a,c   Korhonen, Anna ^a,b   Vaparanta, Katri ^a   Anckar, Julius ^b   Halkilahti, Kalle ^a   Salah, Zaidoun ^d   Aqeilan, Rami I ^d   Palvimo, Jorma J ^e,f   Sistonen, Lea ^b   Elenius, Klaus ^a,c  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d HEBREW UNIVERSITY   (Israel)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CENTRAL NERVOUS SYSTEMS; E3 LIGASE; INHIBITORY EFFECT; INTRACELLULAR DOMAIN; ISOFORMS; MAMMARY EPITHELIAL CELLS; MAMMARY GLAND; NUCLEAR BODIES; NUCLEAR DOMAIN; NUCLEAR LOCALIZATION SIGNAL; OVER-EXPRESSION; PROMYELOCYTIC LEUKEMIA; PROTEIN INHIBITORS; RECEPTOR TYROSINE KINASE; REGULATION OF TRANSCRIPTION; REGULATORY MECHANISM; SMALL UBIQUITIN-LIKE MODIFIERS; SUMOYLATION;

AMINO ACIDS; DISEASES; ENZYMES; TRANSCRIPTION;

PROTEINS;

EPIDERMAL GROWTH FACTOR RECEPTOR 4; PROTEIN INHIBITOR; PROTEIN INHIBITOR OF ACTIVATED STAT3; PROTEIN KINASE YES; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; SUMO 1 PROTEIN; SUMO PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; ENZYME REGULATION; EPITHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; RNA INTERFERENCE; SUMOYLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BREAST NEOPLASMS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; FEMALE; HEK293 CELLS; HUMANS; MAMMARY GLANDS, HUMAN; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; PROTEIN INHIBITORS OF ACTIVATED STAT; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SUMOYLATION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84863304974     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.335927     Document Type: Article

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