Small interference RNA targeting TLR4 gene effectively attenuates pulmonary inflammation in a rat model

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Wu, Feixiang ^a   Liu, Yantao ^a   Lv, Xin ^a   Miao, Xuerong ^a   Sun, Yuming ^a   Yu, Weifeng ^a  

^a Eastern Hepatobiliary Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; SMALL INTERFERING RNA; SODIUM CHLORIDE; TOLL LIKE RECEPTOR 4; CYTOKINE; MESSENGER RNA;

ACUTE LUNG INJURY; ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DOWN REGULATION; EDEMA; ENZYME ASSAY; FEASIBILITY STUDY; GENE TARGETING; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CYTOLOGY; DISEASE MODEL; GENE SILENCING; GENETICS; INTRANASAL DRUG ADMINISTRATION; LUNG; LUNG EDEMA; METABOLISM; PATHOLOGY; RESPIRATORY TRACT MUCOSA; SPRAGUE DAWLEY RAT;

ADENOVIRIDAE; ANIMALIA; RATTUS;

ACUTE LUNG INJURY; ADENOVIRIDAE; ADMINISTRATION, INTRANASAL; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; GENE KNOCKDOWN TECHNIQUES; LIPOPOLYSACCHARIDES; LUNG; MALE; PNEUMONIA; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MUCOSA; RNA, MESSENGER; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 4;

EID: 84863279168     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/406435     Document Type: Article

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