The role of the N-domain in the atpase activity of the mammalian AAA ATPase p97/VCP

Journal of Biological Chemistry

Volumn 287, Issue 11, 2012, Pages 8561-8570

  Niwa, Hajime ^a,b   Ewens, Caroline A ^a   Tsang, Chun ^a   Yeung, Heidi O ^a   Zhang, Xiaodong ^a   Freemont, Paul S ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; ATP-ASE ACTIVITY; ATPASE DOMAIN; C-TERMINAL REGIONS; CELLULAR ACTIVITIES; FLEXIBLE CONFORMATION; FRONTOTEMPORAL DEMENTIAS; HEXAMERS; HUMAN DISEASE; INCLUSION BODIES; N-TERMINAL DOMAINS; STRUCTURE-BASED; TYPE II; WILD TYPES;

BONE; HYDROLYSIS; MAMMALS;

CONFORMATIONS;

ADENOSINE TRIPHOSPHATE; DISULFIDE; PROTEIN P97; VALOSIN CONTAINING PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; HYDROLYSIS; INCLUSION BODY MYOPATHY; MOUSE; MUTAGENESIS; MYOPATHY; NONHUMAN; PAGET BONE DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; CELL CYCLE PROTEINS; FRONTOTEMPORAL DEMENTIA; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; MUTAGENESIS; MUTATION, MISSENSE; OSTEITIS DEFORMANS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

MAMMALIA;

EID: 84863272299     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.302778     Document Type: Article

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