Tyrosine phosphorylation regulates cell cycle-dependent nuclear localization of Cdc48p

Molecular Biology of the Cell

Volumn 9, Issue 1, 1998, Pages 131-141

  Madeo, Frank ^a   Schlauer, Jan ^a,b   Zischka, Hans ^a,c   Mecke, Dieter ^a   Fröhlich, Kai Uwe ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CELL CYCLE PROTEIN; SIGNAL PEPTIDE; TYROSINE; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN;

ARTICLE; CELL CYCLE; CELL NUCLEUS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0031932987     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.1.131     Document Type: Article

References (35)

1. Acharya, U., Jacobs, R., Peters, J.M., Watson, N., Farquhar, M.G., and Malhotra, V. (1995). The formation of Golgi stacks from vesic- ulated Golgi membranes requires two distinct fusion events. Cell 82, 895-904.
2. Bartel, P., Chien, C., Sternglanz, R., and Fields, S. (1993). Elimination of false positives that arise in using the two-hybrid system. BioTechniques 14, 920-924.
3. Biggins, S., Ivanovska, I., and Rose, M.D. (1996). Yeast ubiquitin-like genes are involved in duplication of the microtubule organizing center. J. Cell Biol. 133, 1331-1346.
4. 2cyclins. EMBO J. 12, 3417-3426.
5. Broach, J.R., Li, Y.-Y., Wu, L.-C.C., and Jayaram, M. (1983). Vectors for high-level, inducible expression of cloned genes in yeast. In Experimental Manipulation of Gene Expression, ed. M. Inouye, London: Academic Press, 83-117.
6. Cesarone, C.F., Bolognesi, C., and Santi, L. (1979). Improved microfluorometric DNA determination in biological material using 33258 Hoechst. Anal. Biochem. 100, 188-197.
7. Donaldson, A.D., and Kilmartin, J.V. (1996). Spc42p: a phosphorylated component of the S. cerevisiae spindle pole body (SPB) with an essential function during SPB duplication. J. Cell Biol. 132, 887-901.
8. Egerton, M., Ashe, O.R., Chen, D., Druker, B.J., Burgess, W.H., and Samelson, L.E. (1992). VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation. EMBO J. 11, 3533-3540.
9. Egerton, M., and Samelson, L.E. (1994). Biochemical characterization of valosin-containing protein, a protein tyrosine kinase substrate in hematopoietic cells. J. Biol. Chem. 269, 11435-11441.
10. Errede, B., Gartner, A., Zhou, Z., Nasmyth, K., and Ammerer, G. (1993). MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature 362, 261-264.
11. Friedman, D.B., Sundberg, H.A., Huang, E.Y., and Davis, T.N. (1996). The 110-kD spindle pole body component of Saccharomyces cerevisiae is a phosphoprotein that is modified in a cell cycle-dependent manner. J. Cell Biol. 132, 903-914.
12. Fröhlich, K.-U., Fries, H.-W., Rüdiger, M., Erdmann, R., Botstein, D., and Mecke, D. (1991). Yeast cell cycle protein CDC48p shows full length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J. Cell Biol. 114, 443-453.
13. Fröhlich, K.-U., Fries, H.W., Peters, J.-M., and Mecke, D. (1995). The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependency on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM. Biochim. Biophys. Acta 1253, 25-32.
14. Gasser, S.M. (1983). Import of polypeptides into isolated yeast mitochondria. Methods Enzymol. 97, 329-336.
15. Gebhardt, R., and Jung, W. (1982). Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide. J. Cell Sci. 56, 233-244.
16. Hartwell, L.H., Mortimer, R.K., Culotti, J., and Culotti, M. (1973). Genetic control of the cell-division cycle in yeast: V. Genetic analysis of cdc mutants. Genetics 74, 267-286.
17. Hunter, T., and Plowman, G.D. (1997). The protein kinases of budding yeast: six score and more. Trends Biochem. Sci. 22, 18-22.
18. Ide, G.J., and Saunders, C.A. (1981). Rapid isolation of yeast nuclei. Curr. Genet. 4, 85-90.
19. Kilmartin, J.V., and Adams, A.E. M. (1984). Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J. Cell Biol. 98, 922-933.
20. Koller, K.J., and Brownstein, M.J. (1987). Use of a cDNA clone to identify a supposed precursor protein containing valosin. Nature 325, 542-545.
21. Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
22. Latterich, M., Fröhlich, K.-U., and Schekman, R. (1995). Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes. Cell 82, 885-893.
23. Lim, M.-Y., Dailey, D., Martin, G.S., and Thorner, J. (1993). Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J. Biol. Chem. 268, 21155-21164.
24. Moir, D., Steward, S.E., Osmond, B.C., and Botstein, D. (1982). Cold-sensitive cell-division-cycle mutants of yeast: isolation, properties, and pseudoreversion studies. Genetics 100, 547-563.
25. Moll, T., Tebb, G., Surana, U., Robitsch, H., and Nasmyth, K. (1991). The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5. Cell 66, 743-758.
26. Peters, J.-M., Walsh, M.J., and Franke, W.W. (1990). An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF. EMBO J. 9, 1757-1767.
27. Pringle, J.R., Preston, R.A., Adams, A.E. M., Stearns, T., Drubin, D.G., Haarer, B.K., and Jones, E.W. (1989). Fluorescence microscopy methods for yeast. Methods Cell Biol. 31, 357-435.
28. Rabouille, C., Levine, T.P., Peters, J.M., and Warren, G. (1995). An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. Cell 82, 905-914.
29. Sidorova, J.M., Mikesell, G.E., and Breeden, L.L. (1995). Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol. Biol. Cell 6, 1641-1658.
30. Steinhilber, G., Sproll, M.W., Wolff, J.M., and Anderer, F.A. (1990). Highly specific characterization of tyrosine phosphoproteins in tumor cells based on monoclonal antibodies defined by conjugated phosphotyramine. Anticancer Res. 10, 907-911.
31. Stern, D.F., Zheng, P., Beidler, D.R., and Zerillo, C. (1991). Spk1, a new kinase from Saccharomyces cerevisiae, phosphorylates proteins on serine, threonine, and tyrosine. Mol. Cell. Biol. 11, 987-1001.
32. Tagawa, T., Kuroki, T., Vogt, P.K., and Chida, K. (1995). The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal. J. Cell Biol. 130, 255-263.
33. Vandromme, M., Gauthier-Rouviere, C., Lamb, N., and Fernandez, A. (1996). Regulation of transcription factor localization: fine-tuning of gene expression. Trends Biochem. Sci. 21, 59-64.
34. Wickramasinghe, D., and Albertini, D.F. (1992). Centrosome phosphorylation and the developmental expression of meiotic competence in mouse oocytes. Dev. Biol. 152, 62-74.
35. Wilson, L.K., Benton, B.M., Zhou, S., Thorner, J., and Martin, G.S. (1995). The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptpl. J. Biol. Chem 270, 25185-25193.