Functional characterization of allelic variants of polymorphic human cytochrome P450 2A6 (CYP2A6*5, *7, *8, *18, *19, and *35)

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 3, 2012, Pages 394-399

  Han, Songhee ^a   Choi, Seunghye ^a   Chun, Young Jin ^b   Yun, Chul Ho ^c   Lee, Chang Hoon ^d   Shin, Hee Jung ^e   Na, Han Sung ^e   Chung, Myeon Woo ^e   Kim, Donghak ^a  

^a Konkuk University   (South Korea)

^b Chung Ang University   (South Korea)

^c Chonnam National University   (South Korea)

^d Dongguk University   (South Korea)

^e Korea Food and Drug Administration   (South Korea)

Author keywords

Allelic variant; Coumarin; CYP 2A6; Nicotine; P450; Polymorphism

Indexed keywords

COUMARIN; CYTOCHROME P450 2A6; IMIDAZOLE; NICOTINE; UMBELLIFERONE;

ALLELE; ARTICLE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG OXIDATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE MUTATION; GENETIC VARIABILITY; HUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ARYL HYDROCARBON HYDROXYLASES; COUMARINS; HUMANS; HYDROXYLATION; IMIDAZOLES; NADP; NICOTINE; OXIDATION-REDUCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINANT PROTEINS;

EID: 84863259839     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.35.394     Document Type: Article

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