Physalin B from Physalis angulata triggers the NOXA-related apoptosis pathway of human melanoma A375 cells

Food and Chemical Toxicology

Volumn 50, Issue 3-4, 2012, Pages 619-624

  Hsu, Chia Chun ^a,b   Wu, Yang Chang ^a,c   Farh, Lynn ^d   Du, Ying Chi ^a   Tseng, Wei Kung ^e   Wu, Chau Chung ^f   Chang, Fang Rong ^a,g  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b Paochien Care Cooperation Paochien Hospital   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL PINGTUNG UNIVERSITY   (Taiwan)

^e E DA HOSPITAL   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^g KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Melanoma; NOXA; Physalin B

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; DNA TOPOISOMERASE; PHOSPHATIDYLSERINE; PHYSALIN B; PROTEIN BAX; PROTEIN NOXA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MELANOMA CELL; NONHUMAN; PROTEIN EXPRESSION; RAT;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; HUMANS; INHIBITORY CONCENTRATION 50; MELANOMA; PHYSALIS; PROTO-ONCOGENE PROTEINS C-BCL-2; SECOSTEROIDS;

MURINAE; PHYSALIS ANGULATA;

EID: 84863252040     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.12.017     Document Type: Article

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