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Volumn 34, Issue 4, 2012, Pages 199-209

Withania somnifera chemotypes NMITLI 101R, NMITLI 118R, NMITLI 128R and withaferin A protect Mastomys coucha from Brugia malayi infection

Author keywords

Chemotype; Infective larvae; Lymphatic filariasis; Th1 Th2 cytokine; Withaferin A; Withania somnifera

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 4; REACTIVE OXYGEN METABOLITE; WITHAFERIN A; WITHANIA SOMNIFERA EXTRACT;

EID: 84863251489     PISSN: 01419838     EISSN: 13653024     Source Type: Journal    
DOI: 10.1111/j.1365-3024.2012.01352.x     Document Type: Article
Times cited : (36)

References (42)
  • 3
    • 0006121537 scopus 로고
    • Anonymous. New Delhi, India, CSIR
    • Anonymous. In The Wealth of India, (Raw Materials). New Delhi, India, CSIR, 1976; 10: 580-585.
    • (1976) In The Wealth of India, (Raw Materials) , vol.10 , pp. 580-585
  • 4
    • 73949113574 scopus 로고    scopus 로고
    • Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis
    • Koduru S, Kumar R, Srinivasan S, Evers MB & Damodaran C. Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis. Mol Cancer Ther 2010; 9: 202-210.
    • (2010) Mol Cancer Ther , vol.9 , pp. 202-210
    • Koduru, S.1    Kumar, R.2    Srinivasan, S.3    Evers, M.B.4    Damodaran, C.5
  • 5
    • 65249139441 scopus 로고    scopus 로고
    • Inhibition of monosodium urate crystal-induced inflammation by Withaferin A
    • Sabina EP, Chandal S & Rasool MK. Inhibition of monosodium urate crystal-induced inflammation by Withaferin A. J Pharm Pharm Sci 2008; 11: 46-55.
    • (2008) J Pharm Pharm Sci , vol.11 , pp. 46-55
    • Sabina, E.P.1    Chandal, S.2    Rasool, M.K.3
  • 6
    • 50949114261 scopus 로고    scopus 로고
    • Protective role of Withaferin-A on 7, 12-dimethylbenz (a) anthracene-induced genotoxicity in bone marrow of Syrian golden hamsters
    • Panjamurthy K, Manoharan S, Menon VP, Nirmal MR & Senthil N. Protective role of Withaferin-A on 7, 12-dimethylbenz (a) anthracene-induced genotoxicity in bone marrow of Syrian golden hamsters. J Biochem Mol Toxicol 2008; 22: 251-258.
    • (2008) J Biochem Mol Toxicol , vol.22 , pp. 251-258
    • Panjamurthy, K.1    Manoharan, S.2    Menon, V.P.3    Nirmal, M.R.4    Senthil, N.5
  • 7
    • 0029871546 scopus 로고    scopus 로고
    • Antitumor and radio sensitizing effects of withaferin A on mouse ehrlich ascites carcinoma in vivo A
    • Chandrashekar S, Solomon FE, Devi PU, Udupa N & Srinivasan KK. Antitumor and radio sensitizing effects of withaferin A on mouse ehrlich ascites carcinoma in vivo A. Acta Oncol 1996; 35: 95-100.
    • (1996) Acta Oncol , vol.35 , pp. 95-100
    • Chandrashekar, S.1    Solomon, F.E.2    Devi, P.U.3    Udupa, N.4    Srinivasan, K.K.5
  • 8
    • 0031418908 scopus 로고    scopus 로고
    • Antioxidant activity of glycowithanolides from Withania somnifera
    • Bhattacharya SK, Satyan KS & Ghosal S. Antioxidant activity of glycowithanolides from Withania somnifera. Indian J Exp Biol 1997; 35: 236-239.
    • (1997) Indian J Exp Biol , vol.35 , pp. 236-239
    • Bhattacharya, S.K.1    Satyan, K.S.2    Ghosal, S.3
  • 9
    • 84856314781 scopus 로고    scopus 로고
    • Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice
    • Kushwaha S, Roy S, Maity R, et al. Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice. Vaccine 2012; 30: 1083-1093.
    • (2012) Vaccine , vol.30 , pp. 1083-1093
    • Kushwaha, S.1    Roy, S.2    Maity, R.3
  • 10
    • 70349981456 scopus 로고    scopus 로고
    • Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity
    • Chaurasiya ND, Sangwan RS, Misra LN, Tuli R & Sangwan NS. Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity. Fitoterapia 2009; 80: 496-505.
    • (2009) Fitoterapia , vol.80 , pp. 496-505
    • Chaurasiya, N.D.1    Sangwan, R.S.2    Misra, L.N.3    Tuli, R.4    Sangwan, N.S.5
  • 11
    • 0014859385 scopus 로고
    • Development of Brugia pahangi in the jird, Meriones unguiculatus, with notes on infections in other rodents
    • Ash LR & Riley JM. Development of Brugia pahangi in the jird, Meriones unguiculatus, with notes on infections in other rodents. J Parasitol 1970; 56: 962-968.
    • (1970) J Parasitol , vol.56 , pp. 962-968
    • Ash, L.R.1    Riley, J.M.2
  • 12
    • 55249111256 scopus 로고    scopus 로고
    • Vaccination with 73kDa recombinant heavy chain myosin generates high level of protection against Brugia malayi challenge in jird and mastomys models
    • Vedi S, Dangi A, Hajela K & Bhattacharya SM. Vaccination with 73kDa recombinant heavy chain myosin generates high level of protection against Brugia malayi challenge in jird and mastomys models. Vaccine 2008; 26: 5997-6005.
    • (2008) Vaccine , vol.26 , pp. 5997-6005
    • Vedi, S.1    Dangi, A.2    Hajela, K.3    Bhattacharya, S.M.4
  • 13
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 14
    • 0018792763 scopus 로고
    • Comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (E.L.I.S.A.)
    • Speiser F & Weiss N. Comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (E.L.I.S.A.). Experientia 1979; 35: 1512-1514.
    • (1979) Experientia , vol.35 , pp. 1512-1514
    • Speiser, F.1    Weiss, N.2
  • 15
    • 67349229767 scopus 로고    scopus 로고
    • The n-hexane and chloroform fractions of Piper betle L. trigger different arms of immune responses in BALB/c mice and exhibit antifilarial activity against human lymphatic filarid Brugia malayi
    • Singh M, Shakya S, Soni VK, Dangi A, Kumar N & Bhattacharya SM. The n-hexane and chloroform fractions of Piper betle L. trigger different arms of immune responses in BALB/c mice and exhibit antifilarial activity against human lymphatic filarid Brugia malayi. Int Immunopharmacol 2009; 9: 716-728.
    • (2009) Int Immunopharmacol , vol.9 , pp. 716-728
    • Singh, M.1    Shakya, S.2    Soni, V.K.3    Dangi, A.4    Kumar, N.5    Bhattacharya, S.M.6
  • 16
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
    • O'Brien J, Wilson I, Orton T & Pognan F. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem 2003; 267: 5421-5426.
    • (2003) Eur J Biochem , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4
  • 17
    • 27744476617 scopus 로고    scopus 로고
    • Immunomodulatory and therapeutic properties of the Nigella sativa L. seed
    • Salem ML. Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. Int Immunopharmacol 2005; 5: 1749-1770.
    • (2005) Int Immunopharmacol , vol.5 , pp. 1749-1770
    • Salem, M.L.1
  • 18
    • 84863242439 scopus 로고    scopus 로고
    • Anticancer and immunomodulatory properties of Tinospora
    • ed.) herbal drugs: DOI Berlin Heidelberg: Springer.
    • Mittal A & Singh RP. Anticancer and immunomodulatory properties of Tinospora, Ranawat K.G. (ed.) herbal drugs: Ethnomedicine to modern medicine. DOI Berlin Heidelberg: Springer; 2009. 195-206.
    • (2009) Ethnomedicine to modern medicine , pp. 195-206
    • Mittal, A.1    Singh, R.P.2    Ranawat, K.G.3
  • 19
    • 0037317078 scopus 로고    scopus 로고
    • Study of Immunomodulatory activity of Haridradi Ghrita in rats
    • Fulzele SV, Satturwar PM & Joshi SB. Study of Immunomodulatory activity of Haridradi Ghrita in rats. Indian J Pharmacol, 2003; 35: 51-54.
    • (2003) Indian J Pharmacol , vol.35 , pp. 51-54
    • Fulzele, S.V.1    Satturwar, P.M.2    Joshi, S.B.3
  • 21
    • 0036901923 scopus 로고    scopus 로고
    • Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases
    • Lai JH. Immunomodulatory effects and mechanisms of plant alkaloid tetrandrine in autoimmune diseases. Acta Pharmacol Sin 2002; 23: 1093-1101.
    • (2002) Acta Pharmacol Sin , vol.23 , pp. 1093-1101
    • Lai, J.H.1
  • 22
    • 34249689586 scopus 로고    scopus 로고
    • Oxidative stress in brain and antioxidant activity of Ocimum sanctum in noise exposure
    • Samjon J, Sheeladevi R & Ravindran R. Oxidative stress in brain and antioxidant activity of Ocimum sanctum in noise exposure. Neurotoxicology 2007; 28: 679-685.
    • (2007) Neurotoxicology , vol.28 , pp. 679-685
    • Samjon, J.1    Sheeladevi, R.2    Ravindran, R.3
  • 24
    • 29744467876 scopus 로고    scopus 로고
    • Antiulcer and antioxidant activity of Asparagus racemosus WIILD and Withania somnifera DUNN in rats
    • Bhatnagar M, Sisodia SS & Bhatnagar R. Antiulcer and antioxidant activity of Asparagus racemosus WIILD and Withania somnifera DUNN in rats. Ann N Y Acad Sci 2005; 1056: 261-278.
    • (2005) Ann N Y Acad Sci , vol.1056 , pp. 261-278
    • Bhatnagar, M.1    Sisodia, S.S.2    Bhatnagar, R.3
  • 25
    • 0035682347 scopus 로고    scopus 로고
    • Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects
    • Singh DD, Dey CS & Bhutani KK. Downregulation of p34cdc2 expression with aqueous fraction from Withania somnifera for a possible molecular mechanism of anti-tumor and other pharmacological effects. Phytomedicine 2001; 8: 492-494.
    • (2001) Phytomedicine , vol.8 , pp. 492-494
    • Singh, D.D.1    Dey, C.S.2    Bhutani, K.K.3
  • 26
    • 0033845752 scopus 로고    scopus 로고
    • Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review
    • Mishra LC, Singh BB & Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000; 5: 334-346.
    • (2000) Altern Med Rev , vol.5 , pp. 334-346
    • Mishra, L.C.1    Singh, B.B.2    Dagenais, S.3
  • 27
    • 0034016203 scopus 로고    scopus 로고
    • Adaptogenic and cardioprotective action of ashwagandha in rats and frogs
    • Dhuley JN. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs. J Ethnopharmacol 2000; 70: 57-63.
    • (2000) J Ethnopharmacol , vol.70 , pp. 57-63
    • Dhuley, J.N.1
  • 28
    • 52249091980 scopus 로고    scopus 로고
    • T-cell regulation in helminth parasite infections: implications for inflammatory diseases
    • Maizels R & Yazdanbakhsh M. T-cell regulation in helminth parasite infections: implications for inflammatory diseases. Chem Immunol Allergy 2008; 94: 112-123.
    • (2008) Chem Immunol Allergy , vol.94 , pp. 112-123
    • Maizels, R.1    Yazdanbakhsh, M.2
  • 29
    • 0038444152 scopus 로고    scopus 로고
    • T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4
    • Spencer L, Shultz L & Rajan TV. T cells are required for host protection against Brugia malayi but need not produce or respond to interleukin-4. Infect Immun 2003; 71: 3097-3106.
    • (2003) Infect Immun , vol.71 , pp. 3097-3106
    • Spencer, L.1    Shultz, L.2    Rajan, T.V.3
  • 30
    • 33344457149 scopus 로고    scopus 로고
    • What causes lymphocyte hyporesponsiveness during filarial nematode infections?
    • Harnett W & Harnett MM. What causes lymphocyte hyporesponsiveness during filarial nematode infections? Trends Parasitol 2006; 22: 105-110.
    • (2006) Trends Parasitol , vol.22 , pp. 105-110
    • Harnett, W.1    Harnett, M.M.2
  • 31
    • 0032903768 scopus 로고    scopus 로고
    • Long-term persistence of cellular hyporesponsiveness to filarial antigens after clearance of microfilaremia
    • Gopinath R, Hanna LE, Swami VK, et al. Long-term persistence of cellular hyporesponsiveness to filarial antigens after clearance of microfilaremia. Am J Trop Med Hyg 1999; 60: 848-853.
    • (1999) Am J Trop Med Hyg , vol.60 , pp. 848-853
    • Gopinath, R.1    Hanna, L.E.2    Swami, V.K.3
  • 32
    • 0034055570 scopus 로고    scopus 로고
    • Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokine IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift
    • Doetze A, Satoguina J, Burchard G, et al. Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by Th3/Tr1-type cytokine IL-10 and transforming growth factor-β but not by a Th1 to Th2 shift. Int Immunol 2000; 12: 623-630.
    • (2000) Int Immunol , vol.12 , pp. 623-630
    • Doetze, A.1    Satoguina, J.2    Burchard, G.3
  • 33
    • 33646884472 scopus 로고    scopus 로고
    • F4/80+ alternatively activated macrophages control CD4+ T cells hyporesponsiveness at sites peripheral to filarial infection
    • Taylor MD, Harris A, Nair MG, Maizels RM & allen JE. F4/80+ alternatively activated macrophages control CD4+ T cells hyporesponsiveness at sites peripheral to filarial infection. J Immunol 2006; 176: 6918-6927.
    • (2006) J Immunol , vol.176 , pp. 6918-6927
    • Taylor, M.D.1    Harris, A.2    Nair, M.G.3    Maizels, R.M.4    Allen, J.E.5
  • 34
    • 0023472902 scopus 로고
    • The evasion of the immune response and immunological unresponsiveness: parasitic helminth infections
    • Soulsby EJ. The evasion of the immune response and immunological unresponsiveness: parasitic helminth infections. Immunol Lett 1987; 16: 315-320.
    • (1987) Immunol Lett , vol.16 , pp. 315-320
    • Soulsby, E.J.1
  • 35
    • 57449084307 scopus 로고    scopus 로고
    • Expansion of Foxp3+ regulatory t cells in mice infected with the filarial parasite Brugia malayi
    • McSorley HJ, Harcus YM, Murray J, Taylor MD & Maizels RM. Expansion of Foxp3+ regulatory t cells in mice infected with the filarial parasite Brugia malayi. J Immunol 2008; 181: 6456-6466.
    • (2008) J Immunol , vol.181 , pp. 6456-6466
    • McSorley, H.J.1    Harcus, Y.M.2    Murray, J.3    Taylor, M.D.4    Maizels, R.M.5
  • 37
    • 0033022540 scopus 로고    scopus 로고
    • Immunity in experimental murine filariasis: roles of T and B cells revisited
    • Babu S, Shultz LD, Klei TR & Rajan TV. Immunity in experimental murine filariasis: roles of T and B cells revisited. Infect Immun 1999; 67: 3166-3167.
    • (1999) Infect Immun , vol.67 , pp. 3166-3167
    • Babu, S.1    Shultz, L.D.2    Klei, T.R.3    Rajan, T.V.4
  • 38
    • 33644503187 scopus 로고    scopus 로고
    • Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence
    • Babu S, Blauvelt CP, Kumaraswami V & Nutman TB. Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence. J Immunol 2006; 176: 3248-3256.
    • (2006) J Immunol , vol.176 , pp. 3248-3256
    • Babu, S.1    Blauvelt, C.P.2    Kumaraswami, V.3    Nutman, T.B.4
  • 41
    • 0028261482 scopus 로고
    • Prospects and perspectives of natural plants products in medicine
    • Gupta SS. Prospects and perspectives of natural plants products in medicine. Indian J Pharmacol 1994; 26: 1-12.
    • (1994) Indian J Pharmacol , vol.26 , pp. 1-12
    • Gupta, S.S.1
  • 42
    • 72149101583 scopus 로고    scopus 로고
    • Immunostimulatory complexes containing Eimeria tenella antigens and low toxicity plant saponins induce antibody response and provide protection from challenge in broiler chickens
    • Berezin VE, Bogoyavlenskyi AP, Khudiakova SS, et al. Immunostimulatory complexes containing Eimeria tenella antigens and low toxicity plant saponins induce antibody response and provide protection from challenge in broiler chickens. Vet Parasitol 2010; 167: 28-35.
    • (2010) Vet Parasitol , vol.167 , pp. 28-35
    • Berezin, V.E.1    Bogoyavlenskyi, A.P.2    Khudiakova, S.S.3


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