Rheonix CARD® technology: An innovative and fully automated molecular diagnostic device

Point of Care

Volumn 11, Issue 1, 2012, Pages 42-51

  Spizz, Gwendolyn ^a   Young, Lincoln ^a   Yasmin, Rubina ^a   Chen, Zongyuan ^a   Lee, Travis ^a   Mahoney, Deborah ^a   Zhang, Xun ^a   Mouchka, Greg ^a   Thomas, Benjamin ^a   Honey, Whitney ^a   Roswech, Todd ^a   McGuire, I Cristina ^a   Montagna, Richard ^a   Zhou, Peng ^a  

^a Rheonix Inc   (United States)

Author keywords

infectious disease; integrated molecular assay; molecular diagnostics; POC testing; Rheonix CARD Technology; SNP detection; STI detection

Indexed keywords

EID: 84863248792     PISSN: 1533029X     EISSN: 15330303     Source Type: Journal    
DOI: 10.1097/POC.0b013e318222e184     Document Type: Article

References (33)

1. Wagar EA. Direct hybridization and amplification applications for the diagnosis of infectious diseases [review]. J Clin Lab Anal. 1996;10:312-325.
2. Choo QL, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from a blood-borne nonYA, nonYB viral hepatitis genome. Science. 1989;244:359-362.
3. Williams WJ, Radulovic S, Dasch GA, et al. Identification of Rickettsia conorii infection by polymerase reaction in a soldier returning from Somalia. Clin Infect Dis. 1994;19:93-99.
4. Yamashita Y, Kohno S, Koga H, et al. Detection of Bacteroides fragilis in clinical specimens by PCR. J Clin Microbiol. 1994;32:679-683.
5. Anderson JR, Smith MD, Kibbler CC, et al. A nosocomial outbreak due to non-encapsulated Haemophilus influenzae: Analysis of plasmids coding for antibiotic resistance. J Hosp Infect. 1994;27:17-27.
6. Cormican MG, Glennon M, Riain UN, et al. Evaluation of a PCR assay for detection of Mycobacterium tuberculosis in clinical specimens. Diag Microbiol Infect Dis. 1995;22:357-360.
7. Enroth H, Engstrand L. Immunomagnetic separation and PCR for detection of Helicobacter pylori in water and stool specimens. J Clin Microbiol. 1995;33:2162-2165.
8. Mathis A, Deplazes P. PCR and in vitro cultivation for detection of Leishmania spp. in diagnostic samples from humans and dogs. J Clin Microbiol. 1995;33:1145-1149.
9. Whelen AC, Felmlee TA, Hunt JM, et al. Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-Tube heminested PCR. J Clin Microbiol. 1995;33:556-561.
10. Jackson KM, Edwards RM, Bowden DS, et al. Evaluation of the Roche Amplicor polymerase chain reaction system for detection of Mycobacterium tuberculosis complex in specimens. Pathology. 1996;28:65-67.
11. Pachl C, Todd JA, Kern DG, et al. Rapid and precise quantification of HIV-1 RNA in plasma using a branched DNA signal amplification assay. J AIDS. 1995;8:446-454.
12. Detmer J, Lagier R, Flynn J, et al. Accurate quantification of HCV RNA from all HCV genotypes using branched DNA (bDNA) technology. J Clin Microbiol. 1996;34:901-907.
13. Saksela K, Stevens CE, Rubinstein P, et al. HIV-1 messenger RNA in peripheral blood mononuclear cells as an early marker of risk for progression to AIDS. Ann Intern Med. 1995;123:641-648.
14. Revets H, Marissens D, de Wit S, et al. Comparative evaluation of NASBA HIV-1 RNA QT, Amplicor-HIV monitor, and Quantiplex HIV RNA assay, three methods for quantification of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol. 1996;34:1058-1064.
15. Mellors JW, Kingsley LA, Rinaldo CR, et al. Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann Intern Med. 1995;122:573-579.
16. O'Brien TR, Blattner WA, Waters D, et al. Serum HIV-1 RNA levels and time to development of AIDS in the multicenter hemophilia cohort study. JAMA. 1996;276:105-110.
17. Mellors JM, Rinaldo CR Jr, Gupta P, et al. Prognosis in HIV-1 infection predicted by the quantity of virus in plasma. Science. 1996;272:1167-1170.
18. Cichon S, Nöthen MM, Rietschel M, et al. Pharmacogenetics of schizophrenia. Am J Med Genet. 2000;97(1):98-106.
19. Schwarz UI. Clinical relevance of genetic polymorphism in the human CYP2CP gene. Eur J Clin Invest. 2003;33(suppl 2):23-30.
20. Clayton TA, Lindon JC, Cloarec O, et al. Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature. 2006;440(7087):1073-1077.
21. Shastry BS. Pharmacogenetics and the concept of individualized medicine. Pharmacogenomics J. 2006;6(1):16-21.
22. Oldenburg J, Watzka M, Rost S, et al. VKORC1: Molecular target of coumarins. J Thromb Haemost. 2007;5(suppl 1):1-6.
23. Mansour JC, Schwarz RE. Molecular mechanisms for individualized cancer care. J Am Coll Surg. 2008;207(2):250-258.
24. van't Veer LJ, Bernards R. Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature. 2008;452(7187):564-570.
25. Zhou P, Young L, Chen Z. Weak solvent based chip lamination and characterization of on-chip valve and pump. Biomed Microdevices. 2010;12:821-832.
26. Zhang Y, Coyne MY, Will SG, et al. Single-base mutational analysis of cancer and genetic diseases using membrane bound modified oligonucleotides. Nucleic Acids Res. 1991;19:3929-3933.
27. Rosenblum BB, Lee LG, Spurgeon SL, et al. New dye-labeled terminators for improved DNA sequencing patterns. Nucleic Acid Res. 1997;25:4500-4504.
28. Heiner CR, Kunkapiller KL, Chen S-M, et al. Sequencing multimegabase-Template DNA with BigDye terminator chemistry. Genome Res. 1998;8:557-561.
29. Jeney C, Takacs T, Sebe A, et al. Detection and typing of 46 genital human papillomaviruses by the L1F/L1R primer system based multiplex PCR and hybridization. J Virol Methods. 2007;140:32-42.
30. Daly AK, King BP. Pharmacogenetics of oral anticoagulants. Pharmacogenetics. 2003;13:247-252.
31. Takahashi H, Eschizen H. Pharmacogenetics of warfarin elimination and its clinical implications. Clin Pharmacokinet. 2001;40:587-603.
32. Schwarz UI, Ritchie MD, Bradford Y, et al. Genetic determinants of response to warfarin during initial anticoagulation. N Engl J Med. 2008;358:999-1008.
33. Osinbowale O, Al Malki M, Schade A, et al. An algorithm for managing warfarin resistance. Clev Clin J Med. 2009;76:724-730.