Endothelial neuropilin disruption in mice causes digeorge syndrome-like malformations via mechanisms distinct to those caused by loss of tbx1

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Zhou, Jingjing ^a   Pashmforoush, Mohammad ^a   Sucov, Henry M ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN; NEUROPILIN; PROTEIN TYROSINE KINASE; TEK PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CLEFT PALATE; CONGENITAL BLOOD VESSEL MALFORMATION; CONGENITAL HEART DISEASE; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DIGEORGE SYNDROME; EMBRYO; ENDOTHELIAL DYSFUNCTION; GENE; GENE FUNCTION; GENE INTERACTION; GENE LOSS; GROWTH INHIBITION; HEART OUTPUT; HEART VENTRICLE SEPTUM DEFECT; MOUSE; NEUROPILIN 1 GENE; NONHUMAN; ORGAN SIZE; PHARYNGEAL ORGAN GROWTH IMPAIRMENT; PHARYNX DISEASE; TBX1 GENE; THYMUS DISEASE; THYMUS HYPOPLASIA; THYMUS SIZE; VEGFA GENE; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CELL MOTION; CYTOLOGY; DISEASE MODEL; ENDOTHELIUM; GENE DELETION; GENETICS; MESODERM; METABOLISM; MORPHOGENESIS; MOUSE MUTANT; MUTATION; NEURAL CREST; PHENOTYPE;

MUS;

ANIMALS; APOPTOSIS; CELL MOVEMENT; CELL PROLIFERATION; DIGEORGE SYNDROME; DISEASE MODELS, ANIMAL; ENDOTHELIUM; GENE DELETION; MESODERM; MICE; MICE, MUTANT STRAINS; MODELS, BIOLOGICAL; MORPHOGENESIS; MUTATION; NEURAL CREST; NEUROPILINS; PHENOTYPE; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 84863238892     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032429     Document Type: Article

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