EBV-encoded LMP1 upregulates igκ 3′enhancer activity and Igκ expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Liu, Haidan ^a,b   Duan, Zhi ^a   Zheng, Hui ^a   Hu, Duosha ^a   Li, Ming ^a   Tao, Yongguang ^a   Bode, Ann M ^c   Dong, Zigang ^c   Cao, Ya ^a  

^a Central South University   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; IMMUNOGLOBULIN KAPPA CHAIN; LATENT MEMBRANE PROTEIN 1; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR ETS 1; EBV ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN BARR VIRUS; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; ENZYME INHIBITOR; ETS1 PROTEIN, HUMAN; FLAVONOID; IGK; IMMUNOGLOBULIN; MATRIX PROTEIN; OLIGONUCLEOTIDE;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENHANCER REGION; ENZYME INHIBITION; EPSTEIN BARR VIRUS; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN KAPPA LIGHT CHAIN GENE; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; MUTATIONAL ANALYSIS; NASOPHARYNX CANCER; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REPORTER GENE; SIGNAL TRANSDUCTION; UPREGULATION; GENETICS; METABOLISM; NASOPHARYNX CARCINOMA; NASOPHARYNX TUMOR; PHOSPHORYLATION; RNA INTERFERENCE; TUMOR CELL LINE;

HUMAN HERPESVIRUS 4;

BINDING SITES; CELL LINE, TUMOR; DNA MUTATIONAL ANALYSIS; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOGLOBULINS; NASOPHARYNGEAL NEOPLASMS; OLIGONUCLEOTIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEIN C-ETS-1; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VIRAL MATRIX PROTEINS;

EID: 84863236801     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032624     Document Type: Article

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