Effects of the endothelin ETA-receptor antagonist FR139317 on development of hypertension and cardiovascular hypertrophy in deoxycorticosterone acetate-salt hypertensive rats

Japanese Journal of Pharmacology

Volumn 70, Issue 4, 1996, Pages 313-319

  Fujita, Katsuya ^a   Matsumura, Yasuo ^a   Miyazaki, Yohko ^a   Takaoka, Masanori ^a   Morimoto, Shiro ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Cardiovascular hypertrophy; Deoxycorticosterone acetate (DOCA) salt hypertension; Endothelin ETA receptor; Endothelin 1; FR139317

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; AZEPINE DERIVATIVE; DEOXYCORTICOSTERONE; ENDOTHELIN; ENDOTHELIN RECEPTOR; INDOLE DERIVATIVE; DEOXYCORTICOSTERONE ACETATE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BLOOD PRESSURE; CARDIOMEGALY; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HYPERTENSION; MALE; MESENTERIC ARTERY; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; THORACIC AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD VESSEL WALL; CONTROLLED STUDY; HEART HYPERTROPHY; HYPERTROPHY; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; SALT LOADING; SYSTOLIC BLOOD PRESSURE;

ANALYSIS OF VARIANCE; ANIMALS; AORTA, THORACIC; AZEPINES; BLOOD PRESSURE; CARDIOMEGALY; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; ENDOTHELINS; HYPERTENSION; INDOLES; MALE; MESENTERIC ARTERIES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN;

EID: 0029665199     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.70.313     Document Type: Article

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