Novel Dual Action AT1 and ETA Receptor Antagonists Reduce Blood Pressure in Experimental Hypertension

Journal of Pharmacology and Experimental Therapeutics

Volumn 309, Issue 1, 2004, Pages 275-284

  Kowala, Mark C ^a,b   Murugesan, Natesan ^a   Tellew, John ^a   Carlson, Kenneth ^a   Monshizadegan, Hossain ^a   Ryan, Carol ^a   Gu, Zhengxiang ^a   Kane, Bridgette ^a   Fadnis, Leena ^a   Baska, Rose Ann ^a   Beyer, Sophie ^a   Arthur, Susan ^a   Dickinson, Kenneth ^a   Zhang, Donglu ^a   Perrone, Mark ^a   Ferrer, Pam ^a   Giancarli, Mary ^a   Baumann, Jergen ^a   Bird, Eileen ^c   Panchal, Balkrushna ^c   Yang, Yifan ^c   Trippodo, Nick ^a   Barrish, Joel ^a   Macor, John E ^a   more..

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^b PFIZER INC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ENDOTHELIN; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; IRBESARTAN; MINERALOCORTICOID; SODIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE REGULATION; CALCIUM TRANSPORT; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; ESSENTIAL HYPERTENSION; HYPERTENSION; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIPHENYL COMPOUNDS; BLOOD PRESSURE; CALCIUM; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; HUMANS; HYPERTENSION; LOSARTAN; MALE; OXAZOLES; RATS; RATS, INBRED SHR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ENDOTHELIN A; SODIUM; SULFONAMIDES; TETRAZOLES;

EID: 12144288600     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.055855     Document Type: Article

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