-
1
-
-
0014139879
-
Brain metabolism during fasting
-
Owen, O., Morgan, A., Kemp, H., Sullivan, J., Herrara, H., and Cahill, G. (1967) Brain metabolism during fasting. J. Clin. Invest. 46, 1589-1595
-
(1967)
J. Clin. Invest.
, vol.46
, pp. 1589-1595
-
-
Owen, O.1
Morgan, A.2
Kemp, H.3
Sullivan, J.4
Herrara, H.5
Cahill, G.6
-
2
-
-
54049143854
-
Lactate fuels the human brain during exercise
-
Quistorff, B., Secher, N. H., and Van Lieshout, J. J. (2008) Lactate fuels the human brain during exercise. FASEB J. 22, 3443-3449
-
(2008)
FASEB J.
, vol.22
, pp. 3443-3449
-
-
Quistorff, B.1
Secher, N.H.2
Van Lieshout, J.J.3
-
3
-
-
80052689581
-
Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans
-
Rasmussen, P., Wyss, M. T., and Lundby, C. (2011) Cerebral glucose and lactate consumption during cerebral activation by physical activity in humans. FASEB J. 25, 2865-2873
-
(2011)
FASEB J.
, vol.25
, pp. 2865-2873
-
-
Rasmussen, P.1
Wyss, M.T.2
Lundby, C.3
-
4
-
-
0034057785
-
Cerebral blood flow and metabolism during exercise
-
Ide, K., and Secher, N. H. (2000) Cerebral blood flow and metabolism during exercise. Prog. Neurobiol. 61, 397-414
-
(2000)
Prog. Neurobiol.
, vol.61
, pp. 397-414
-
-
Ide, K.1
Secher, N.H.2
-
5
-
-
67349095741
-
Blood lactate is an important energy source for the human brain
-
van Hall, G., Stromstad, M., Rasmussen, P., Jans, O., Zaar, M., Gam, C., Quistorff, B., Secher, N. H., and Nielsen, H. B. (2009) Blood lactate is an important energy source for the human brain. J. Cereb. Blood Flow Metab. 29, 1121-1129
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 1121-1129
-
-
Van Hall, G.1
Stromstad, M.2
Rasmussen, P.3
Jans, O.4
Zaar, M.5
Gam, C.6
Quistorff, B.7
Secher, N.H.8
Nielsen, H.B.9
-
6
-
-
0842322960
-
A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain
-
DOI 10.1113/jphysiol.2003.055053
-
Dalsgaard, M. K., Quistorff, B., Danielsen, E. R., Selmer, C., Vogelsang, T., and Secher, N. H. (2004) A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J. Physiol. 554, 571-578 (Pubitemid 38181364)
-
(2004)
Journal of Physiology
, vol.554
, Issue.2
, pp. 571-578
-
-
Dalsgaard, M.K.1
Quistorff, B.2
Danielsen, E.R.3
Selmer, C.4
Vogelsang, T.5
Secher, N.H.6
-
7
-
-
79955424675
-
Cardiac anaplerosis in health and disease: Food for thought
-
Des Rosiers, C., Labarthe, F., Lloyd, S. G., and Chatham, J. C. (2011) Cardiac anaplerosis in health and disease: food for thought. Cardiovasc. Res. 90, 210-219
-
(2011)
Cardiovasc. Res.
, vol.90
, pp. 210-219
-
-
Des Rosiers, C.1
Labarthe, F.2
Lloyd, S.G.3
Chatham, J.C.4
-
8
-
-
79960212377
-
Vigorous exercise increases brain lactate and Glx (glutamate+glutamine): A dynamic 1H-MRS study
-
Maddock, R. J., Casazza, G. A., Buonocore, M. H., and Tanase, C. (2011) Vigorous exercise increases brain lactate and Glx (glutamate+glutamine): a dynamic 1H-MRS study. Neuroimage 57, 1324-1330
-
(2011)
Neuroimage
, vol.57
, pp. 1324-1330
-
-
Maddock, R.J.1
Casazza, G.A.2
Buonocore, M.H.3
Tanase, C.4
-
9
-
-
35848944111
-
The brain at work: A cerebral metabolic manifestation of central fatigue?
-
DOI 10.1002/jnr.21274
-
Dalsgaard, M. K., and Secher, N. H. (2007) The brain at work: a cerebral metabolic manifestation of central fatigue? J. Neurosci. Res. 85, 3334-3339 (Pubitemid 350058521)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.15
, pp. 3334-3339
-
-
Dalsgaard, M.K.1
Secher, N.H.2
-
10
-
-
77953134828
-
Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: Evaluation of the arterial and jugular venous metabolome
-
Rasmussen, P., Nyberg, N., Jaroszewski, J. W., Krogh-Madsen, R., Secher, N. H., and Quistorff, B. (2010) Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome. J. Cereb. Blood Flow Metab. 30, 1240-1246
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 1240-1246
-
-
Rasmussen, P.1
Nyberg, N.2
Jaroszewski, J.W.3
Krogh-Madsen, R.4
Secher, N.H.5
Quistorff, B.6
-
11
-
-
0034465750
-
Are arterial, muscle and working limb lactate exchange data obtained on men at altitude consistent with the hypothesis of an intracellular lactate shuttle?
-
Brooks, G. A. (1999) Are arterial, muscle and working limb lactate exchange data obtained on men at altitude consistent with the hypothesis of an intracellular lactate shuttle? Adv. Exp. Med. Biol. 474, 185-204
-
(1999)
Adv. Exp. Med. Biol.
, vol.474
, pp. 185-204
-
-
Brooks, G.A.1
-
12
-
-
0034795798
-
Evidence of separate pathways for lactate uptake and release by the perfused rat heart
-
Chatham, J. C., Des Rosiers, C., and Forder, J. R. (2001) Evidence of separate pathways for lactate uptake and release by the perfused rat heart. Am. J. Physiol. Endocrinol. Metab. 281, E794-E802
-
(2001)
Am. J. Physiol. Endocrinol. Metab.
, vol.281
-
-
Chatham, J.C.1
Des Rosiers, C.2
Forder, J.R.3
-
13
-
-
79952504220
-
In humans IL-6 is released from the brain during and after exercise and paralleled by enhanced IL-6 mRNA expression in the hippocampus of mice
-
Rasmussen, P., Vedel, J. C., Olesen, J., Adser, H., Pedersen, M. V., Hart, E., Secher, N. H., and Pilegaard, H. (2011) In humans IL-6 is released from the brain during and after exercise and paralleled by enhanced IL-6 mRNA expression in the hippocampus of mice. Acta Physiol. (Oxf.) 201, 475-482
-
(2011)
Acta Physiol. (Oxf.)
, vol.201
, pp. 475-482
-
-
Rasmussen, P.1
Vedel, J.C.2
Olesen, J.3
Adser, H.4
Pedersen, M.V.5
Hart, E.6
Secher, N.H.7
Pilegaard, H.8
-
14
-
-
84863011313
-
Brain glycogen supercompensation following exhaustive exercise
-
Matsui, T., Ishikawa, T., Ito, H., Okamoto, M., Inoue, K., Lee, M.-c., Fujikawa, T., Ichitani, Y., Kawanaka, K., and Soya, H. (2012) Brain glycogen supercompensation following exhaustive exercise. J. Physiol. 590, 607-616
-
(2012)
J. Physiol.
, vol.590
, pp. 607-616
-
-
Matsui, T.1
Ishikawa, T.2
Ito, H.3
Okamoto, M.4
Inoue, K.5
Lee, M.-C.6
Fujikawa, T.7
Ichitani, Y.8
Kawanaka, K.9
Soya, H.10
-
15
-
-
79959734660
-
Brain glycogen decreases during prolonged exercise
-
Matsui, T., Soya, S., Okamoto, M., Ichitani, Y., Kawanaka, K., and Soya, H. (2011) Brain glycogen decreases during prolonged exercise. J. Physiol. 589, 3383-3393
-
(2011)
J. Physiol.
, vol.589
, pp. 3383-3393
-
-
Matsui, T.1
Soya, S.2
Okamoto, M.3
Ichitani, Y.4
Kawanaka, K.5
Soya, H.6
-
16
-
-
66849091841
-
Cerebral oxygenation decreases during exercise in humans with beta-adrenergic blockade
-
Seifert, T., Rasmussen, P., Secher, N. H., and Nielsen, H. B. (2009) Cerebral oxygenation decreases during exercise in humans with beta-adrenergic blockade. Acta Physiol. (Oxf.) 196, 295-302
-
(2009)
Acta Physiol. (Oxf.)
, vol.196
, pp. 295-302
-
-
Seifert, T.1
Rasmussen, P.2
Secher, N.H.3
Nielsen, H.B.4
-
17
-
-
77954491073
-
Reduced muscle activation during exercise related to brain oxygenation and metabolism in humans
-
Rasmussen, P., Nielsen, J., Overgaard, M., Krogh-Madsen, R., Gjedde, A., Secher, N. H., and Petersen, N. C. (2010) Reduced muscle activation during exercise related to brain oxygenation and metabolism in humans. J. Physiol. 588, 1985-1995
-
(2010)
J. Physiol.
, vol.588
, pp. 1985-1995
-
-
Rasmussen, P.1
Nielsen, J.2
Overgaard, M.3
Krogh-Madsen, R.4
Gjedde, A.5
Secher, N.H.6
Petersen, N.C.7
-
18
-
-
0002797665
-
Simple rating for estimation of perceived exertion
-
(Borg, G., ed) Pergamon, New York
-
Borg, G. (1975) Simple rating for estimation of perceived exertion. In Physical Work and Effort (Borg, G., ed) pp. 39-46, Pergamon, New York
-
(1975)
Physical Work and Effort
, pp. 39-46
-
-
Borg, G.1
-
19
-
-
0017229137
-
Angiographically verified transient alteration of intercranial arteries and veins in dependence of different CO2 tension
-
Bradac, G. B., Simon, R. S., and Heidsieck, C. H. (1976) Angiographically verified transient alteration of intercranial arteries and veins in dependence of different CO2 tension. Neuroradiology 10, 257-262
-
(1976)
Neuroradiology
, vol.10
, pp. 257-262
-
-
Bradac, G.B.1
Simon, R.S.2
Heidsieck, C.H.3
-
20
-
-
0033918821
-
MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis
-
Serrador, J. M., Picot, P. A., Rutt, B. K., Shoemaker, J. K., and Bondar, R. L. (2000) MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 31, 1672-1678 (Pubitemid 30437522)
-
(2000)
Stroke
, vol.31
, Issue.7
, pp. 1672-1678
-
-
Serrador, J.M.1
Picot, P.A.2
Rutt, B.K.3
Shoemaker, J.K.4
Bondar, R.L.5
-
21
-
-
0027269702
-
Average blood flow and oxygen uptake in the human brain during resting wakefulness: A critical appraisal of the Kety-Schmidt technique
-
Madsen, P. L., Holm, S., Herning, M., and Lassen, N. A. (1993) Average blood flow and oxygen uptake in the human brain during resting wakefulness: a critical appraisal of the Kety-Schmidt technique. J. Cereb. Blood Flow Metab. 13, 646-655 (Pubitemid 23187508)
-
(1993)
Journal of Cerebral Blood Flow and Metabolism
, vol.13
, Issue.4
, pp. 646-655
-
-
Madsen, P.L.1
Holm, S.2
Herning, M.3
Lassen, N.A.4
-
22
-
-
33751189603
-
MCA Vmean and the arterial lactate-to-pyruvate ratio correlate during rhythmic handgrip
-
Rasmussen, P., Plomgaard, P., Krogh-Madsen, R., Kim, Y. S., van Lieshout, J. J., Secher, N. H., and Quistorff, B. (2006) MCA Vmean and the arterial lactate-to-pyruvate ratio correlate during rhythmic handgrip. J. Appl. Physiol. 101, 1406-1411
-
(2006)
J. Appl. Physiol.
, vol.101
, pp. 1406-1411
-
-
Rasmussen, P.1
Plomgaard, P.2
Krogh-Madsen, R.3
Kim, Y.S.4
Van Lieshout, J.J.5
Secher, N.H.6
Quistorff, B.7
-
23
-
-
0346456853
-
Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain
-
DOI 10.1073/pnas.0307457100
-
Mintun, M. A., Vlassenko, A. G., Rundle, M. M., and Raichle, M. E. (2004) Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain. Proc. Natl. Acad. Sci. U. S. A. 101, 659-664 (Pubitemid 38084693)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.2
, pp. 659-664
-
-
Mintun, M.A.1
Vlassenko, A.G.2
Rundle, M.M.3
Raichle, M.E.4
-
24
-
-
24944516239
-
Cerebral metabolic response to low blood flow: Possible role of cytochrome oxidase inhibition
-
DOI 10.1038/sj.jcbfm.9600113
-
Gjedde, A., Johannsen, P., Cold, G. E., and Østergaard, L. (2005) Cerebral metabolic response to low blood flow: possible role of cytochrome oxidase inhibition. J. Cereb. Blood Flow Metab. 25, 1183-1196 (Pubitemid 41710743)
-
(2005)
Journal of Cerebral Blood Flow and Metabolism
, vol.25
, Issue.9
, pp. 1183-1196
-
-
Gjedde, A.1
Johannsen, P.2
Cold, G.E.3
Ostergaard, L.4
-
25
-
-
33847715143
-
Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humans
-
DOI 10.1038/sj.jcbfm.9600416, PII 9600416
-
Rasmussen, P., Dawson, E. A., Nybo, L., van Lieshout, J. J., Secher, N. H., and Gjedde, A. (2007) Capillary-oxygenationlevel-dependent near-infrared spectrometry in frontal lobe of humans. J. Cereb. Blood Flow Metab. 27, 1082-1093 (Pubitemid 46659036)
-
(2007)
Journal of Cerebral Blood Flow and Metabolism
, vol.27
, Issue.5
, pp. 1082-1093
-
-
Rasmussen, P.1
Dawson, E.A.2
Nybo, L.3
Van Lieshout, J.J.4
Secher, N.H.5
Gjedde, A.6
-
26
-
-
0000127505
-
Determinants of tissue oxygen tension
-
Kety, S. S. (1957) Determinants of tissue oxygen tension. Fed. Proc. 16, 666-671
-
(1957)
Fed. Proc.
, vol.16
, pp. 666-671
-
-
Kety, S.S.1
-
27
-
-
0000648085
-
Influences of glucose loading and of injected insulin on hepatic glucose output
-
Steele, R. (1959) Influences of glucose loading and of injected insulin on hepatic glucose output. Ann. N. Y. Acad. Sci. 82, 420-430
-
(1959)
Ann. N. Y. Acad. Sci.
, vol.82
, pp. 420-430
-
-
Steele, R.1
-
28
-
-
0026699650
-
Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects
-
Rosenblatt, J., Chinkes, D., Wolfe, M., and Wolfe, R. R. (1992) Stable isotope tracer analysis by GC-MS, including quantification of isotopomer effects. Am. J. Physiol. Endocrinol. Metab. 263, E584-E596
-
(1992)
Am. J. Physiol. Endocrinol. Metab.
, vol.263
-
-
Rosenblatt, J.1
Chinkes, D.2
Wolfe, M.3
Wolfe, R.R.4
-
29
-
-
0022292871
-
Systemic lactate kinetics during graded exercise in man
-
Stanley, W. C., Gertz, E. W., Wisneski, J. A., Morris, D. L., Neese, R. A., and Brooks, G. A. (1985) Systemic lactate kinetics during graded exercise in man. Am. J. Physiol. Endocrinol. Metab. 249, E595-E602 (Pubitemid 16171157)
-
(1985)
American Journal of Physiology - Endocrinology and Metabolism
, vol.12
, Issue.6
-
-
Stanley, W.C.1
Gertz, E.W.2
Wisneski, J.A.3
-
30
-
-
71249103087
-
Cell-cell and intracellular lactate shuttles
-
Brooks, G. A. (2009) Cell-cell and intracellular lactate shuttles. J. Physiol. 587, 5591-5600
-
(2009)
J. Physiol.
, vol.587
, pp. 5591-5600
-
-
Brooks, G.A.1
-
31
-
-
77954325418
-
Lactate kinetics in human tissues at rest and during exercise
-
Van Hall, G. (2010) Lactate kinetics in human tissues at rest and during exercise. Acta Physiol. 199, 499-508
-
(2010)
Acta Physiol.
, vol.199
, pp. 499-508
-
-
Van Hall, G.1
-
32
-
-
78649708331
-
Glycogenolysis in astrocytes supports blood-borne glucose channeling not glycogen-derived lactate shuttling to neurons: Evidence from mathematical modeling
-
DiNuzzo, M., Mangia, S., Maraviglia, B., and Giove, F. (2010) Glycogenolysis in astrocytes supports blood-borne glucose channeling not glycogen-derived lactate shuttling to neurons: evidence from mathematical modeling. J. Cereb. Blood Flow Metab. 30, 1895-1904
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 1895-1904
-
-
DiNuzzo, M.1
Mangia, S.2
Maraviglia, B.3
Giove, F.4
-
33
-
-
69249099340
-
Cerebral oxygenation and metabolism during exercise following three months of endurance training in healthy overweight males
-
Seifert, T., Rasmussen, P., Brassard, P., Homann, P. H., Wissenberg, M., Nordby, P., Stallknecht, B., Secher, N. H., and Nielsen, H. B. (2009) Cerebral oxygenation and metabolism during exercise following three months of endurance training in healthy overweight males. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297, R867-R876
-
(2009)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.297
-
-
Seifert, T.1
Rasmussen, P.2
Brassard, P.3
Homann, P.H.4
Wissenberg, M.5
Nordby, P.6
Stallknecht, B.7
Secher, N.H.8
Nielsen, H.B.9
-
34
-
-
0031880556
-
2
-
Richardson, R. S., Noyszewski, E. A., Leigh, J. S., and Wagner, P. D. (1998) Lactate efflux from exercising human skeletal muscle: role of intracellular PO2. J. Appl. Physiol. 85, 627-634 (Pubitemid 28365832)
-
(1998)
Journal of Applied Physiology
, vol.85
, Issue.2
, pp. 627-634
-
-
Richardson, R.S.1
Noyszewski, E.A.2
Leigh, J.S.3
Wagner, P.D.4
-
36
-
-
73449121461
-
Coupling between the blood lactate-to-pyruvate ratio and MCA Vmean at the onset of exercise in humans
-
Rasmussen, P., Madsen, C. A., Nielsen, H. B., Zaar, M., Gjedde, A., Secher, N. H., and Quistorff, B. (2009) Coupling between the blood lactate-to-pyruvate ratio and MCA Vmean at the onset of exercise in humans. J. Appl. Physiol. 107, 1799-1805
-
(2009)
J. Appl. Physiol.
, vol.107
, pp. 1799-1805
-
-
Rasmussen, P.1
Madsen, C.A.2
Nielsen, H.B.3
Zaar, M.4
Gjedde, A.5
Secher, N.H.6
Quistorff, B.7
-
37
-
-
0028080101
-
Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
-
DOI 10.1073/pnas.91.22.10625
-
Pellerin, L., and Magistretti, P. J. (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U. S. A. 91, 10625-10629 (Pubitemid 24329051)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.22
, pp. 10625-10629
-
-
Pellerin, L.1
Magistretti, P.J.2
-
38
-
-
64349101696
-
The in vivo neuron-to-astrocyte lactate shuttle in human brain: Evidence from modeling of measured lactate levels during visual stimulation
-
Mangia, S., Simpson, I. A., Vannucci, S. J., and Carruthers, A. (2009) The in vivo neuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation. J. Neurochem. 109(Suppl 1), 55-62
-
(2009)
J. Neurochem.
, vol.109
, Issue.SUPPL. 1
, pp. 55-62
-
-
Mangia, S.1
Simpson, I.A.2
Vannucci, S.J.3
Carruthers, A.4
-
39
-
-
77958528666
-
The contribution of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy
-
Boumezbeur, F., Petersen, K. F., Cline, G. W., Mason, G. F., Behar, K. L., Shulman, G. I., and Rothman, D. L. (2010) The contribution of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy. J. Neurosci. 30, 13983-13991
-
(2010)
J. Neurosci.
, vol.30
, pp. 13983-13991
-
-
Boumezbeur, F.1
Petersen, K.F.2
Cline, G.W.3
Mason, G.F.4
Behar, K.L.5
Shulman, G.I.6
Rothman, D.L.7
-
40
-
-
79956330533
-
In vivo evidence for lactate as a neuronal energy source
-
Wyss, M. T., Jolivet, R., Buck, A., Magistretti, P. J., and Weber, B. (2011) In vivo evidence for lactate as a neuronal energy source. J. Neurosci. 31, 7477-7485
-
(2011)
J. Neurosci.
, vol.31
, pp. 7477-7485
-
-
Wyss, M.T.1
Jolivet, R.2
Buck, A.3
Magistretti, P.J.4
Weber, B.5
-
41
-
-
0027262320
-
Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy
-
Giller, C. A., Bowman, G., Dyer, H., Mootz, L., Krippner, W., Loftus, C. M., and Muizelaar, J. P. (1993) Cerebral arterial diameters during changes in blood-pressure and carbon-dioxide during craniotomy. Neurosurgery 32, 737-742 (Pubitemid 23134016)
-
(1993)
Neurosurgery
, vol.32
, Issue.5
, pp. 737-742
-
-
Giller, C.A.1
Bowman, G.2
Dyer, H.3
Mootz, L.4
Krippner, W.5
Loftus, C.M.6
Muizelaar, J.P.7
-
42
-
-
0030017310
-
Carotid artery blood flow and middle cerebral artery blood flow velocity during physical exercise
-
Hellström, G., Fischer-Colbrie, W., Wahlgren, N. G., and Jögestrand, T. (1996) Carotid artery blood flow and middle cerebral artery blood flow velocity during physical exercise. J. Appl. Physiol. 81, 413-418
-
(1996)
J. Appl. Physiol.
, vol.81
, pp. 413-418
-
-
Hellström, G.1
Fischer-Colbrie, W.2
Wahlgren, N.G.3
Jögestrand, T.4
-
43
-
-
0026488677
-
Regional cerebral artery mean flow velocity and blood flow during dynamic exercise in humans
-
Jørgensen, L., Perko, M., and Secher, N. H. (1992) Regional cerebral artery mean flow velocity and blood flow during dynamic exercise in humans. J. Appl. Physiol. 73, 1825-1830
-
(1992)
J. Appl. Physiol.
, vol.73
, pp. 1825-1830
-
-
Jørgensen, L.1
Perko, M.2
Secher, N.H.3
|