메뉴 건너뛰기




Volumn 201, Issue 4, 2011, Pages 475-482

In humans IL-6 is released from the brain during and after exercise and paralleled by enhanced IL-6 mRNA expression in the hippocampus of mice

Author keywords

Glycogen; Humans; Metabolism; Mouse

Indexed keywords

GLYCOGEN; INTERLEUKIN 6; MESSENGER RNA;

EID: 79952504220     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02223.x     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 73949138881 scopus 로고    scopus 로고
    • Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes
    • Ball, K.K., Cruz, N.F., Mrak, R.E. & Dienel, G.A. 2010. Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes. J Cereb Blood Flow Metab 30, 162-176.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 162-176
    • Ball, K.K.1    Cruz, N.F.2    Mrak, R.E.3    Dienel, G.A.4
  • 3
    • 63549151154 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain
    • Beurel, E. & Jope, R.S. 2009. Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain. J Neuroinflammation 6, 9.
    • (2009) J Neuroinflammation , vol.6 , pp. 9
    • Beurel, E.1    Jope, R.S.2
  • 5
    • 55749105157 scopus 로고    scopus 로고
    • Effects of physical training on IL-1beta, IL-6 and IL-1ra concentrations in various brain areas of the rat
    • Chennaoui, M., Drogou, C. & Gomez-Merino, D. 2008. Effects of physical training on IL-1beta, IL-6 and IL-1ra concentrations in various brain areas of the rat. Eur Cytokine Netw 19, 8-14.
    • (2008) Eur Cytokine Netw , vol.19 , pp. 8-14
    • Chennaoui, M.1    Drogou, C.2    Gomez-Merino, D.3
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. & Sacchi, N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 7
    • 33745726895 scopus 로고    scopus 로고
    • Fuelling cerebral activity in exercising man
    • Dalsgaard, M.K. 2006. Fuelling cerebral activity in exercising man. J Cereb Blood Flow Metab 26, 731-750.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 731-750
    • Dalsgaard, M.K.1
  • 9
    • 0842322960 scopus 로고    scopus 로고
    • A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain
    • Dalsgaard, M.K., Quistorff, B., Danielsen, E.R., Selmer, C., Vogelsang, T. & Secher, N.H. 2004b. A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J Physiol 554, 571-578.
    • (2004) J Physiol , vol.554 , pp. 571-578
    • Dalsgaard, M.K.1    Quistorff, B.2    Danielsen, E.R.3    Selmer, C.4    Vogelsang, T.5    Secher, N.H.6
  • 11
    • 0035875165 scopus 로고    scopus 로고
    • Exercise increases blood flow to locomotor, vestibular, cardiorespiratory and visual regions of the brain in miniature swine
    • Delp, M., Armstrong, R., Godfrey, D., Laughlin, M., Ross, C. & Wilkerson, M. 2001. Exercise increases blood flow to locomotor, vestibular, cardiorespiratory and visual regions of the brain in miniature swine. J Physiol 533, 849-859.
    • (2001) J Physiol , vol.533 , pp. 849-859
    • Delp, M.1    Armstrong, R.2    Godfrey, D.3    Laughlin, M.4    Ross, C.5    Wilkerson, M.6
  • 12
    • 33748742072 scopus 로고    scopus 로고
    • Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis
    • Ding, Q., Vaynman, S., Souda, P., Whitelegge, J.P. & Gomez-Pinilla, F. 2006. Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis. Eur J Neurosci 24, 1265-1276.
    • (2006) Eur J Neurosci , vol.24 , pp. 1265-1276
    • Ding, Q.1    Vaynman, S.2    Souda, P.3    Whitelegge, J.P.4    Gomez-Pinilla, F.5
  • 14
    • 0023780085 scopus 로고
    • Nonoxidative glucose consumption during focal physiologic neural activity
    • Fox, P.T., Raichle, M.E., Mintun, M.A. & Dence, C. 1988. Nonoxidative glucose consumption during focal physiologic neural activity. Science 241, 462-464.
    • (1988) Science , vol.241 , pp. 462-464
    • Fox, P.T.1    Raichle, M.E.2    Mintun, M.A.3    Dence, C.4
  • 15
    • 0033937544 scopus 로고    scopus 로고
    • Effects of an intravenous catheter on the local production of cytokines and soluble cytokine receptors in healthy men
    • Haack, M., Reichenberg, A., Kraus, T., Schuld, A., Yirmiya, R. & Pollmacher, T. 2000. Effects of an intravenous catheter on the local production of cytokines and soluble cytokine receptors in healthy men. Cytokine 12, 694-698.
    • (2000) Cytokine , vol.12 , pp. 694-698
    • Haack, M.1    Reichenberg, A.2    Kraus, T.3    Schuld, A.4    Yirmiya, R.5    Pollmacher, T.6
  • 16
    • 0034916106 scopus 로고    scopus 로고
    • Effects of sleep on endotoxin-induced host responses in healthy men
    • Haack, M., Schuld, A., Kraus, T. & Pollmacher, T. 2001. Effects of sleep on endotoxin-induced host responses in healthy men. Psychosom Med 63, 568-578.
    • (2001) Psychosom Med , vol.63 , pp. 568-578
    • Haack, M.1    Schuld, A.2    Kraus, T.3    Pollmacher, T.4
  • 17
    • 33751313848 scopus 로고    scopus 로고
    • {Beta}-Adrenergic receptor desensitization in man: insight into post-exercise attenuation of cardiac function
    • Hart, E., Dawson, E., Rasmussen, P., George, K., Secher, N.H., Whyte, G. & Shave, R. 2006. {Beta}-Adrenergic receptor desensitization in man: insight into post-exercise attenuation of cardiac function. J Physiol 577, 717-725.
    • (2006) J Physiol , vol.577 , pp. 717-725
    • Hart, E.1    Dawson, E.2    Rasmussen, P.3    George, K.4    Secher, N.H.5    Whyte, G.6    Shave, R.7
  • 18
    • 0032726855 scopus 로고    scopus 로고
    • Cerebral metabolic response to submaximal exercise
    • Ide, K., Horn, A. & Secher, N. 1999. Cerebral metabolic response to submaximal exercise. J Appl Physiol 87, 1604-1608.
    • (1999) J Appl Physiol , vol.87 , pp. 1604-1608
    • Ide, K.1    Horn, A.2    Secher, N.3
  • 19
    • 0035651023 scopus 로고    scopus 로고
    • Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content
    • Keller, C., Steensberg, A., Pilegaard, H., Osada, T., Saltin, B., Pedersen, B.K. & Neufer, P.D. 2001. Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. FASEB J 15, 2748-2750.
    • (2001) FASEB J , vol.15 , pp. 2748-2750
    • Keller, C.1    Steensberg, A.2    Pilegaard, H.3    Osada, T.4    Saltin, B.5    Pedersen, B.K.6    Neufer, P.D.7
  • 20
    • 44449103306 scopus 로고    scopus 로고
    • Non-selective beta-adrenergic blockade prevents reduction of the cerebral metabolic ratio during exhaustive exercise in humans
    • Larsen, T.S., Rasmussen, P., Overgaard, M., Secher, N.H. & Nielsen, H.B. 2008. Non-selective beta-adrenergic blockade prevents reduction of the cerebral metabolic ratio during exhaustive exercise in humans. J Physiol 586, 2807-2815.
    • (2008) J Physiol , vol.586 , pp. 2807-2815
    • Larsen, T.S.1    Rasmussen, P.2    Overgaard, M.3    Secher, N.H.4    Nielsen, H.B.5
  • 21
    • 0003803484 scopus 로고
    • A Flexible System of Enzymatic Analysis
    • Academic Press, New York.
    • Lowry, O.H. & Passonneau, J.V. 1972. A Flexible System of Enzymatic Analysis. Academic Press, New York.
    • (1972)
    • Lowry, O.H.1    Passonneau, J.V.2
  • 22
    • 30344484849 scopus 로고    scopus 로고
    • Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies
    • Lundby, C., Nordsborg, N., Kusuhara, K., Kristensen, K.M., Neufer, P.D. & Pilegaard, H. 2005. Gene expression in human skeletal muscle: alternative normalization method and effect of repeated biopsies. Eur J Appl Physiol 95, 351-360.
    • (2005) Eur J Appl Physiol , vol.95 , pp. 351-360
    • Lundby, C.1    Nordsborg, N.2    Kusuhara, K.3    Kristensen, K.M.4    Neufer, P.D.5    Pilegaard, H.6
  • 23
    • 0036686906 scopus 로고    scopus 로고
    • Interleukin-6 release from the human brain during prolonged exercise
    • Nybo, L., Nielsen, B., Pedersen, B.K., Moller, K. & Secher, N.H. 2002. Interleukin-6 release from the human brain during prolonged exercise. J Physiol 542, 991-995.
    • (2002) J Physiol , vol.542 , pp. 991-995
    • Nybo, L.1    Nielsen, B.2    Pedersen, B.K.3    Moller, K.4    Secher, N.H.5
  • 24
    • 0041831295 scopus 로고    scopus 로고
    • Association between fatigue and failure to preserve cerebral energy turnover during prolonged exercise
    • Nybo, L., Moller, K., Pedersen, B.K., Nielsen, B. & Secher, N.H. 2003a. Association between fatigue and failure to preserve cerebral energy turnover during prolonged exercise. Acta Physiol Scand 179, 67-74.
    • (2003) Acta Physiol Scand , vol.179 , pp. 67-74
    • Nybo, L.1    Moller, K.2    Pedersen, B.K.3    Nielsen, B.4    Secher, N.H.5
  • 25
  • 26
    • 14844310201 scopus 로고    scopus 로고
    • Cerebral ammonia uptake and accumulation during prolonged exercise in humans
    • Nybo, L., Dalsgaard, M.K., Steensberg, A., Moller, K. & Secher, N.H. 2005. Cerebral ammonia uptake and accumulation during prolonged exercise in humans. J Physiol 563, 285-290.
    • (2005) J Physiol , vol.563 , pp. 285-290
    • Nybo, L.1    Dalsgaard, M.K.2    Steensberg, A.3    Moller, K.4    Secher, N.H.5
  • 27
    • 34247123850 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control
    • Pedersen, B.K. 2006. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem 42, 105-117.
    • (2006) Essays Biochem , vol.42 , pp. 105-117
    • Pedersen, B.K.1
  • 28
    • 0642364997 scopus 로고    scopus 로고
    • Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise
    • Penkowa, M., Keller, C., Keller, P., Jauffred, S. & Pedersen, B.K. 2003. Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise. FASEB J 17, 2166-2168.
    • (2003) FASEB J , vol.17 , pp. 2166-2168
    • Penkowa, M.1    Keller, C.2    Keller, P.3    Jauffred, S.4    Pedersen, B.K.5
  • 29
    • 0033679675 scopus 로고    scopus 로고
    • Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise
    • Pilegaard, H., Ordway, G.A., Saltin, B. & Neufer, P.D. 2000. Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am J Physiol Endocrinol Metab 279, E806-E814.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Pilegaard, H.1    Ordway, G.A.2    Saltin, B.3    Neufer, P.D.4
  • 33
    • 77953134828 scopus 로고    scopus 로고
    • Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome
    • Rasmussen, P., Nyberg, N., Jaroszewski, J.W., Krogh-Madsen, R., Secher, N.H. & Quistorff, B. 2010. Brain nonoxidative carbohydrate consumption is not explained by export of an unknown carbon source: evaluation of the arterial and jugular venous metabolome. J Cereb Blood Flow Metab 30, 1240-1246.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1240-1246
    • Rasmussen, P.1    Nyberg, N.2    Jaroszewski, J.W.3    Krogh-Madsen, R.4    Secher, N.H.5    Quistorff, B.6
  • 34
    • 0036144176 scopus 로고    scopus 로고
    • Activation-induced resetting of cerebral metabolism and flow is abolished by beta-adrenergic blockade with propranolol
    • Schmalbruch, I.K., Linde, R., Paulson, O.B. & Madsen, P.L. 2002. Activation-induced resetting of cerebral metabolism and flow is abolished by beta-adrenergic blockade with propranolol. Stroke 33, 251-255.
    • (2002) Stroke , vol.33 , pp. 251-255
    • Schmalbruch, I.K.1    Linde, R.2    Paulson, O.B.3    Madsen, P.L.4
  • 35
    • 70350450885 scopus 로고    scopus 로고
    • How much is too much? Interleukin-6 and its signalling in atherosclerosis
    • Schuett, H., Luchtefeld, M., Grothusen, C., Grote, K. & Schieffer, B. 2009. How much is too much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost 102, 215-222.
    • (2009) Thromb Haemost , vol.102 , pp. 215-222
    • Schuett, H.1    Luchtefeld, M.2    Grothusen, C.3    Grote, K.4    Schieffer, B.5
  • 36
    • 0035933156 scopus 로고    scopus 로고
    • Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging
    • Shulman, R., Hyder, F. & Rothman, D. 2001. Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc Natl Acad Sci 98, 6417-6422.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 6417-6422
    • Shulman, R.1    Hyder, F.2    Rothman, D.3
  • 37
    • 0035369080 scopus 로고    scopus 로고
    • Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans
    • Starkie, R.L., Arkinstall, M.J., Koukoulas, I., Hawley, J.A. & Febbraio, M.A. 2001. Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans. J Physiol 533, 585-591.
    • (2001) J Physiol , vol.533 , pp. 585-591
    • Starkie, R.L.1    Arkinstall, M.J.2    Koukoulas, I.3    Hawley, J.A.4    Febbraio, M.A.5
  • 38
    • 0035576798 scopus 로고    scopus 로고
    • Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content
    • Steensberg, A., Febbraio, M.A., Osada, T., Schjerling, P., van Hall, G., Saltin, B. & Pedersen, B.K. 2001. Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content. J Physiol 537, 633-639.
    • (2001) J Physiol , vol.537 , pp. 633-639
    • Steensberg, A.1    Febbraio, M.A.2    Osada, T.3    Schjerling, P.4    van Hall, G.5    Saltin, B.6    Pedersen, B.K.7
  • 40
    • 23044499225 scopus 로고    scopus 로고
    • Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt
    • Weigert, C., Hennige, A.M., Brodbeck, K., Haring, H.U. & Schleicher, E.D. 2005. Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt. Am J Physiol Endocrinol Metab 289, E251-E257.
    • (2005) Am J Physiol Endocrinol Metab , vol.289
    • Weigert, C.1    Hennige, A.M.2    Brodbeck, K.3    Haring, H.U.4    Schleicher, E.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.