-
1
-
-
4744347762
-
Mechanism of Androgen-Refractory Prostate Cancer
-
Debes JD, Tindall DJ, (2004) Mechanism of Androgen-Refractory Prostate Cancer. N Engl J Med 351: 1488-1490.
-
(2004)
N Engl J Med
, vol.351
, pp. 1488-1490
-
-
Debes, J.D.1
Tindall, D.J.2
-
2
-
-
0036219874
-
Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault
-
Arnold JT, Isaacs JT, (2002) Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault. Endocrine-Related Cancer 9: 61-73.
-
(2002)
Endocrine-Related Cancer
, vol.9
, pp. 61-73
-
-
Arnold, J.T.1
Isaacs, J.T.2
-
3
-
-
77953442022
-
Update on options for treatment of metastatic castration-resistant prostate cancer
-
Vishnu P, Tan WW, (2010) Update on options for treatment of metastatic castration-resistant prostate cancer. Onco Targets Ther 3: 39-51.
-
(2010)
Onco Targets Ther
, vol.3
, pp. 39-51
-
-
Vishnu, P.1
Tan, W.W.2
-
5
-
-
58549108859
-
The role of PTEN/AKT/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
-
Dubrovska A, Kim S, Salamone RJ, Walker JR, Maira SM, et al. (2009) The role of PTEN/AKT/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci USA 106: 268-273.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 268-273
-
-
Dubrovska, A.1
Kim, S.2
Salamone, R.J.3
Walker, J.R.4
Maira, S.M.5
-
6
-
-
45549091414
-
Prostate cancer stem cells: a new target for therapy
-
Maitland NJ, Collins AT, (2008) Prostate cancer stem cells: a new target for therapy. J Clin Oncol 26: 2862-2870.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2862-2870
-
-
Maitland, N.J.1
Collins, A.T.2
-
7
-
-
33645026803
-
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
-
Patrawala L, Calhoun T, Schneider-Broussard R, Li H, Bhatia B, et al. (2006) Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25: 1696-1708.
-
(2006)
Oncogene
, vol.25
, pp. 1696-1708
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Li, H.4
Bhatia, B.5
-
8
-
-
4444262529
-
CD133, a novel marker for human prostatic epithelial stem cells
-
Neal DE, Maitland NJ, Collins AT, (2005) CD133, a novel marker for human prostatic epithelial stem cells. Journal of Cell Science 117: 3539-3545.
-
(2005)
Journal of Cell Science
, vol.117
, pp. 3539-3545
-
-
Neal, D.E.1
Maitland, N.J.2
Collins, A.T.3
-
9
-
-
57149090285
-
The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells
-
Vander Griend DJ, Karthaus WL, Dalrymple S, Meeker A, DeMarzo AM, (2008) The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells. Cancer Res 68: 9703-9711.
-
(2008)
Cancer Res
, vol.68
, pp. 9703-9711
-
-
Vander Griend, D.J.1
Karthaus, W.L.2
Dalrymple, S.3
Meeker, A.4
DeMarzo, A.M.5
-
10
-
-
34248140257
-
Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens
-
Miki J, Furusato B, Li H, Gu Y, Takahashi H, et al. (2007) Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens. Cancer Res 67: 3153-3161.
-
(2007)
Cancer Res
, vol.67
, pp. 3153-3161
-
-
Miki, J.1
Furusato, B.2
Li, H.3
Gu, Y.4
Takahashi, H.5
-
11
-
-
33846259375
-
Prostate cancer stem/progenitor cells: identification, characterization, and implications
-
Tang DG, Patrawala L, Calhoun T, Bhatia B, Choy G, et al. (2007) Prostate cancer stem/progenitor cells: identification, characterization, and implications. Mol Carcinol 46: 1-14.
-
(2007)
Mol Carcinol
, vol.46
, pp. 1-14
-
-
Tang, D.G.1
Patrawala, L.2
Calhoun, T.3
Bhatia, B.4
Choy, G.5
-
12
-
-
78650312347
-
Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma
-
Dubrovska A, Elliott J, Salamone RJ, Kim S, Aimone LJ, et al. (2010) Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma. Clin Cancer Res 16: 5692-5702.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5692-5702
-
-
Dubrovska, A.1
Elliott, J.2
Salamone, R.J.3
Kim, S.4
Aimone, L.J.5
-
13
-
-
9444239192
-
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis
-
Darash-Yahana M, Pikarsky E, Abramovitch R, Zeira E, Pal B, et al. (2004) Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J 18: 1240-1242.
-
(2004)
FASEB J
, vol.18
, pp. 1240-1242
-
-
Darash-Yahana, M.1
Pikarsky, E.2
Abramovitch, R.3
Zeira, E.4
Pal, B.5
-
14
-
-
33646422999
-
CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins
-
Engl T, Relja B, Marian D, Blumenberg C, Müller I, et al. (2006) CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins. Neoplasia 8: 290-301.
-
(2006)
Neoplasia
, vol.8
, pp. 290-301
-
-
Engl, T.1
Relja, B.2
Marian, D.3
Blumenberg, C.4
Müller, I.5
-
15
-
-
10044284415
-
CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion
-
Singh S, Singh UP, Grizzle WE, Lillard JW Jr, (2004) CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest 84: 1666-1676.
-
(2004)
Lab Invest
, vol.84
, pp. 1666-1676
-
-
Singh, S.1
Singh, U.P.2
Grizzle, W.E.3
Lillard Jr., J.W.4
-
16
-
-
0033485625
-
Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells
-
Burger JA, Burger M, Kipps TJ, (1999) Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells. Blood 94: 3658-3667.
-
(1999)
Blood
, vol.94
, pp. 3658-3667
-
-
Burger, J.A.1
Burger, M.2
Kipps, T.J.3
-
17
-
-
0042355606
-
CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease
-
Barretina J, Juncà J, Llano A, Gutiérrez A, Flores A, et al. (2003) CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease. Ann Hematol 82: 500-505.
-
(2003)
Ann Hematol
, vol.82
, pp. 500-505
-
-
Barretina, J.1
Juncà, J.2
Llano, A.3
Gutiérrez, A.4
Flores, A.5
-
18
-
-
47749109823
-
The role of CXC chemokines and their receptors in cancer
-
Vandercappellen J, Van Damme J, Struyf S, (2008) The role of CXC chemokines and their receptors in cancer. Cancer Lett 28: 226-244.
-
(2008)
Cancer Lett
, vol.28
, pp. 226-244
-
-
Vandercappellen, J.1
van Damme, J.2
Struyf, S.3
-
19
-
-
46849102804
-
New insights on the role of CXCR4 in cancer metastasis
-
Zlotnik A, (2008) New insights on the role of CXCR4 in cancer metastasis. J Pathol 215: 211-213.
-
(2008)
J Pathol
, vol.215
, pp. 211-213
-
-
Zlotnik, A.1
-
20
-
-
77953348723
-
CXCR4 and cancer
-
Furusato B, Mohamed A, Uhlén M, Rhim JS, (2010) CXCR4 and cancer. Pathol Int 60: 497-505.
-
(2010)
Pathol Int
, vol.60
, pp. 497-505
-
-
Furusato, B.1
Mohamed, A.2
Uhlén, M.3
Rhim, J.S.4
-
21
-
-
58149314184
-
CXCR4 mediates the proliferation of glioblastoma progenitor cells
-
Ehtesham M, Mapara KY, Stevenson CB, Thompson RC, (2009) CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Lett 274: 305-312.
-
(2009)
Cancer Lett
, vol.274
, pp. 305-312
-
-
Ehtesham, M.1
Mapara, K.Y.2
Stevenson, C.B.3
Thompson, R.C.4
-
22
-
-
33751319000
-
Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
-
Pan J, Mestas J, Burdick MD, Phillips RJ, Thomas GV, et al. (2006) Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 5: 56.
-
(2006)
Mol Cancer
, vol.5
, pp. 56
-
-
Pan, J.1
Mestas, J.2
Burdick, M.D.3
Phillips, R.J.4
Thomas, G.V.5
-
23
-
-
77249178726
-
Basal epithelial cells are efficient targets for prostate cancer initiation
-
Lawson DA, Zong Y, Memarzadeh S, Xin L, Huang J, et al. (2010) Basal epithelial cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci USA 107: 2610-2615.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2610-2615
-
-
Lawson, D.A.1
Zong, Y.2
Memarzadeh, S.3
Xin, L.4
Huang, J.5
-
24
-
-
72249113369
-
Lin-Sca-1+ CD49f high stem/progenitors are tumor initiating cells in the PTEN-null prostate cancer model
-
Mulholland DJ, Xin L, Morin A, Lawson D, Witte ON, (2009) Lin-Sca-1+ CD49f high stem/progenitors are tumor initiating cells in the PTEN-null prostate cancer model. Cancer Res 69: 8555-8562.
-
(2009)
Cancer Res
, vol.69
, pp. 8555-8562
-
-
Mulholland, D.J.1
Xin, L.2
Morin, A.3
Lawson, D.4
Witte, O.N.5
-
25
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON, (2010) Identification of a cell of origin for human prostate cancer. Science 329: 568-571.
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
26
-
-
29344451650
-
CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12
-
Chinni SR, Sivalogan S, Dong Z, Filho JC, Deng X, et al. (2006) CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12. Prostate 66: 32-48.
-
(2006)
Prostate
, vol.66
, pp. 32-48
-
-
Chinni, S.R.1
Sivalogan, S.2
Dong, Z.3
Filho, J.C.4
Deng, X.5
-
27
-
-
33646782964
-
FOXO factors: a matter of life and death
-
Huang H, Tindall DJ, (2006) FOXO factors: a matter of life and death. Future Oncol 2: 83-89.
-
(2006)
Future Oncol
, vol.2
, pp. 83-89
-
-
Huang, H.1
Tindall, D.J.2
-
28
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, et al. (2007) Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1: 101-112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
-
29
-
-
57449114150
-
Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells
-
Zhu S, Evans S, Yan B, Povsic TJ, Tapson V, et al. (2008) Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells. Circulation 118: 2156-2165.
-
(2008)
Circulation
, vol.118
, pp. 2156-2165
-
-
Zhu, S.1
Evans, S.2
Yan, B.3
Povsic, T.J.4
Tapson, V.5
-
30
-
-
65649095605
-
CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway
-
Wu Y, Peng H, Cui M, Whitney NP, Huang Y, et al. (2009) CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway. J Neurochem 109: 1157-1167.
-
(2009)
J Neurochem
, vol.109
, pp. 1157-1167
-
-
Wu, Y.1
Peng, H.2
Cui, M.3
Whitney, N.P.4
Huang, Y.5
-
31
-
-
0032540493
-
Genomic organization and promoter characterization of human CXCR4 gene
-
Caruz A, Samsom M, Alonso JM, Alcami J, Baleux F, et al. (1998) Genomic organization and promoter characterization of human CXCR4 gene. FEBS Lett 426: 271-278.
-
(1998)
FEBS Lett
, vol.426
, pp. 271-278
-
-
Caruz, A.1
Samsom, M.2
Alonso, J.M.3
Alcami, J.4
Baleux, F.5
-
32
-
-
33748075143
-
A FoxO-Smad synexpression group in human keratinocytes
-
Gomis RR, Alarcón C, He W, Wang Q, Seoane J, et al. (2006) A FoxO-Smad synexpression group in human keratinocytes. Proc Natl Acad Sci U S A 103: 12747-12752.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12747-12752
-
-
Gomis, R.R.1
Alarcón, C.2
He, W.3
Wang, Q.4
Seoane, J.5
-
33
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, et al. (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
-
34
-
-
33845769269
-
Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells
-
Sun YX, Fang M, Wang J, Cooper CR, Pienta KJ, et al. (2007) Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells. Prostate 67: 61-73.
-
(2007)
Prostate
, vol.67
, pp. 61-73
-
-
Sun, Y.X.1
Fang, M.2
Wang, J.3
Cooper, C.R.4
Pienta, K.J.5
-
35
-
-
53849143245
-
Integrins in prostate cancer progression
-
Goel HL, Li J, Kogan S, Languino LR, (2008) Integrins in prostate cancer progression. Endocr Relat Cancer 3: 657-664.
-
(2008)
Endocr Relat Cancer
, vol.3
, pp. 657-664
-
-
Goel, H.L.1
Li, J.2
Kogan, S.3
Languino, L.R.4
-
36
-
-
76649108219
-
Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events
-
Struckhoff AP, Vitko JR, Rana MK, Davis CT, Foderingham KE, et al. (2010) Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events. J Cell Sci 123: 401-412.
-
(2010)
J Cell Sci
, vol.123
, pp. 401-412
-
-
Struckhoff, A.P.1
Vitko, J.R.2
Rana, M.K.3
Davis, C.T.4
Foderingham, K.E.5
-
37
-
-
33846254013
-
Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias
-
Zeng Z, Samudio IJ, Munsell M, An J, Huang Z, et al. (2006) Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias. Mol Cancer Ther 5: 3113-3121.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 3113-3121
-
-
Zeng, Z.1
Samudio, I.J.2
Munsell, M.3
An, J.4
Huang, Z.5
-
38
-
-
0037085938
-
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone
-
Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, et al. (2002) Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 62: 1832-1837.
-
(2002)
Cancer Res
, vol.62
, pp. 1832-1837
-
-
Taichman, R.S.1
Cooper, C.2
Keller, E.T.3
Pienta, K.J.4
Taichman, N.S.5
-
39
-
-
0036091414
-
The Role of αvβ3 in Prostate Cancer Progression
-
Cooper CR, Chay CH, Pienta KJ, (2002) The Role of αvβ3 in Prostate Cancer Progression. Neoplasia 4: 191-194.
-
(2002)
Neoplasia
, vol.4
, pp. 191-194
-
-
Cooper, C.R.1
Chay, C.H.2
Pienta, K.J.3
-
40
-
-
0033118450
-
Prostatic carcinoma cell migration via αVβ3 integrin is modulated by a focal adhesion kinase pathway
-
Zheng D-Q, Woodward AS, Fornaro M, Tallini G, Languino LR, (1999) Prostatic carcinoma cell migration via αVβ3 integrin is modulated by a focal adhesion kinase pathway. Cancer Res 59: 1655-1664.
-
(1999)
Cancer Res
, vol.59
, pp. 1655-1664
-
-
Zheng, D.-Q.1
Woodward, A.S.2
Fornaro, M.3
Tallini, G.4
Languino, L.R.5
-
41
-
-
69449103735
-
Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth
-
Porvasnik S, Sakamoto N, Kusmartsev S, Eruslanov E, Kim WJ, et al. (2009) Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth. Prostate 69: 1460-1469.
-
(2009)
Prostate
, vol.69
, pp. 1460-1469
-
-
Porvasnik, S.1
Sakamoto, N.2
Kusmartsev, S.3
Eruslanov, E.4
Kim, W.J.5
-
42
-
-
77954064420
-
Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers
-
Hwang-Verslues WW, Kuo WH, Chang PH, Pan CC, Wang HH, et al. (2009) Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers. PLoS One 4: e8377.
-
(2009)
PLoS One
, vol.4
-
-
Hwang-Verslues, W.W.1
Kuo, W.H.2
Chang, P.H.3
Pan, C.C.4
Wang, H.H.5
-
43
-
-
7044269527
-
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
-
Passegué E, Wagner EF, Weissman IL, (2004) JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119: 431-443.
-
(2004)
Cell
, vol.119
, pp. 431-443
-
-
Passegué, E.1
Wagner, E.F.2
Weissman, I.L.3
-
44
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson CH, Ailles LE, Dylla SJ, Muijtjens M, Jones C, et al. (2004) Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 351: 657-667.
-
(2004)
N Engl J Med
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
Ailles, L.E.2
Dylla, S.J.3
Muijtjens, M.4
Jones, C.5
|