Thioredoxin glutathione reductase as a novel drug target: Evidence from schistosoma japonicum

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Song, LiJun ^a   Li, JiaHuang ^b   Xie, ShuYing ^c   Qian, ChunYan ^a   Wang, Jie ^a   Zhang, Wei ^a   Yin, XuRen ^a   Hua, ZiChun ^b   Yu, ChuanXin ^a  

^a BEIJING HOSPITAL   (China)

^b NANJING UNIVERSITY   (China)

^c Jiangxi Institute of Parasitic Diseases   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AURANOFIN; GLUTAREDOXIN; GLUTATHIONE REDUCTASE; OXIDOREDUCTASE; RECOMBINANT PROTEIN; THIOREDOXIN GLUTATHIONE REDUCTASE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; ENZYME INHIBITOR; MESSENGER RNA; MULTIENZYME COMPLEX; SELENIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTHELMINTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; PARASITE LOAD; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; EXPRESSED SEQUENCE TAG; HELMINTH; HOMEOSTASIS; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS;

MAMMALIA; MUS; PLATYHELMINTHES; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI;

ANIMALS; AURANOFIN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENZYME INHIBITORS; EXPRESSED SEQUENCE TAGS; HELMINTHS; HOMEOSTASIS; KINETICS; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; RNA, MESSENGER; SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SELENIUM;

EID: 84863158643     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031456     Document Type: Article

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