Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione

Journal of Biological Chemistry

Volumn 283, Issue 26, 2008, Pages 17898-17907

  Bonilla, Mariana ^a   Denicola, Ana ^b   Novoselov, Sergey V ^c   Turanov, Anton A ^c   Protasio, Anna ^a   Izmendi, Darwin ^a   Gladyshev, Vadim N ^c   Salinas, Gustavo ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; DEVELOPING COUNTRIES; ELECTRIC GROUNDING; ENZYMES; HYSTERESIS; MAMMALS; MEDICAL PROBLEMS; SELENIUM;

ACTIVITY LOSSES; AURANOFIN; CYTOSOLIC; DO-MAINS; DRUG TARGETS; GLUTAREDOXIN DOMAINS; GLUTATHIONE; GLUTATHIONE REDUCTASES; GLUTATHIONYLATION; HOMODIMERIC ENZYMES; HYSTERETIC BEHAVIORS; IN VITRO; MAMMALIAN HOSTS; REDOX CENTERS; SELENIUM ANDS; SELENOCYSTEINE; THIOREDOXIN; THIOREDOXIN REDUCTASES; THIOREDOXINS;

PROTEINS;

AURANOFIN; CYSTEINE; GLUTATHIONE; GLUTATHIONE REDUCTASE; INSULIN; SELENIUM; SELENOCYSTEINE; THIOREDOXIN REDUCTASE; ENZYME INHIBITOR; MULTIENZYME COMPLEX; OXIDOREDUCTASE; THIOREDOXIN GLUTATHIONE REDUCTASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOSOL; ECHINOCOCCOSIS; ECHINOCOCCUS GRANULOSUS; GENE MUTATION; HYSTERESIS; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATION REDUCTION REACTION; PLATYHELMINTH; PRIORITY JOURNAL; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; HOMEOSTASIS; KINETICS; METABOLISM; MITOCHONDRION; PROTEIN TERTIARY STRUCTURE;

ECHINOCOCCUS GRANULOSUS; MAMMALIA; PLATYHELMINTHES;

ANIMALS; CYTOSOL; ECHINOCOCCUS GRANULOSUS; ENZYME INHIBITORS; GLUTATHIONE; HOMEOSTASIS; KINETICS; MITOCHONDRIA; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; PLATYHELMINTHS; PROTEIN STRUCTURE, TERTIARY; SELENIUM; SELENOCYSTEINE;

EID: 49649083647     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710609200     Document Type: Article

References (40)

1. WHO (2006) Preventive Chemotherapy in Human Helminthiasis: Coordinated Use of Antihelminthic Drugs in Control Interventions: a Manual for Health Professionals and Programme Managers, WHO Press, World Health Organization, Geneva, Switzerland
2. Mansour, T. (2002) in Chemotherapeutic Targets in Parasites: Contemporary Strategies (Mansour, T., ed) pp. 58-89, Cambridge University Press, Cambridge
3. Doenhoff, M. J., and Pica-Mattoccia, L. (2006) Expert Rev. Anti Infect. Ther. 4, 199-210
4. Alger, H. M., and Williams, D. L. (2002) Mol. Biochem. Parasitol. 121, 129-139
5. Agorio, A., Chalar, C., Cardozo, S., and Salinas, G. (2003) J. Biol. Chem. 278, 12920-12928
6. Rendón, J. L., del Arenal, I. P., Guevara-Flores, A., Uribe, A., Plancarte, A., and Mendoza-Hernández, G. (2004) Mol. Biochem. Parasitol. 133, 61-69
7. Salinas, G., Selkirk, M. E., Chalar, C., Maizels, R. M., and Fernández, C. (2004) Trends Parasitol. 20, 340-346
8. Kuntz, A. N., Davioud-Charvet, E., Sayed, A. A., Califf, L. L., Dessolin, J., Arnér, E. S., and Williams, D. L. (2007) PLoS Med. 4, e206
9. Fernandes, A. P., and Holmgren, A. (2004) Antioxid. Redox Signal. 6, 63-74
10. Winyard, P. G., Moody, C. J., and Jacob, C. (2005) Trends Biochem. Sci. 30, 453-461
11. Turanov, A. A., Su, D., and Gladyshev, V. N. (2006) J. Biol. Chem. 281, 22953-22963
12. Miranda-Vizuete, A., Damdimopoulos, A. E., Pedrajas, J. R., Gustafsson, J.-A., and Spyrou, G. (1999) Eur. J. Biochem. 261, 405-412
13. Sun, Q.-A., Kirnarsky, L., Sherman, S., and Gladyshev, V. N. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3673-3678
14. Kelner, M. J., and Montoya, M. A. (2000) Biochem. Biophys. Res. Commun. 269, 366-368
15. Gromer, S., Arscott, L. D., Williams, C. H., Jr., Schirmer, R. H., and Becker, K. (1998) J. Biol. Chem. 273, 20096-20101
16. Sun, Q.-A., Yalin, W., Zappacosta, F., Jeang, K.-T., Lee, B. J., Hatfield, D. L., and Gladyshev, V. N. (1999) J. Biol. Chem. 274, 24522-24530
17. Sun, Q. A., Su, D., Novoselov, S. V., Carlson, B. A., Hatfield, D. L., and Gladyshev, V. N. (2005) Biochemistry 44, 14528-14537
18. Angelucci, F., Miele, A. E., Boumis, G., Dimastrogiovanni, D., Brunori, M., and Bellelli, A. (2008) Proteins, in press
19. Arnér, E. S., Sarioglu, H., Lottspeich, F., Holmgren, A., and Bock, A. (1999) J. Mol. Biol. 292, 1003-1016
20. Rengby, O., Johansson, L., Carlson, L. A., Serini, E., Vlamis-Gardikas, A., Karsnas, P., and Arnér, E. S. (2004) Appl. Environ. Microbiol. 70, 5159-5167
21. Bar-Noy, S., Gorlatov, S. N., and Stadtman, T. C. (2001) Free Radic. Biol. Med. 30, 51-61
22. Müller, S., Heider, J., and Böck, A. (1997) Arch. Microbiol. 168, 421-427
23. Chalar, C., Martinez, C., Agorio, A., Salinas, G., Soto, J., and Ehrlich, R. (1999) Biochem. Biophys. Res. Commun. 262, 302-307
24. Holmgren, A. (1979) J. Biol. Chem. 254, 9627-9632
25. Arnér, E. S., Zhong, L., and Holmgren, A. (1999) Methods Enzymol. 300, 226-239
26. Carlberg, I., and Mannervik, B. (1985) Methods Enzymol. 113, 484-490
27. Alger, H. M., Sayed, A. A., Stadecker, M. J., and Williams, D. L. (2002) Int. J. Parasitol. 32, 1285-1292
28. Holmgren, A. (2006) in Selenium: Its Molecular Biology and Role in Human Health, 2nd Ed. (Hatfield, D. L., Berry, M. J., and Gladyshev, V. N., eds) pp. 183-194, Springer, New York
29. Zhong, L., and Holmgren, A. (2000) J. Biol. Chem. 275, 18121-18128
30. Frieden, C. (1970) J. Biol. Chem. 245, 5788-5799
31. Beer, S. M., Taylor, E. R., Brown, S. E., Dahm, C. C., Costa, N. J., Runswick, M. J., and Murphy, M. P. (2004) J. Biol. Chem. 279, 47939-47951
32. Johansson, C., Lillig, C. H., and Holmgren, A. (2004) J. Biol. Chem. 279, 7537-7543
33. Lillig, C. H., Potamitou, A., Schwenn, J. D., Vlamis-Gardikas, A., and Holmgren, A. (2003) J. Biol. Chem. 278, 22325-22330
34. Gallogly, M. M., and Mieyal, J. J. (2007) Curr. Opin. Pharmacol. 7, 381-391
35. Niwa, T. (2007) J. Chromatogr. B 855, 59-65
36. Biterova, E. I., Turanov, A. A., Gladyshev, V. N., and Barycki, J. J. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15018-15023
37. Eckenroth, B., Harris, K., Turanov, A. A., Gladyshev, V. N., Raines, R. T., and Hondal, R. J. (2006) Biochemistry 45, 5158-5170
38. Eckenroth, B. E., Lacey, B. M., Lothrop, A. P., Harris, K. M., and Hondal, R. J. (2007) Biochemistry 46, 9472-9483
39. Gromer, S., Johansson, L., Bauer, H., Arscott, L. D., Rauch, S., Ballou, D. P., Williams, C. H., Jr., Schirmer, R. H., and Arnér, E. S. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 12618-12623
40. Gladyshev, V. N. (2006) in Selenium: Its Molecular Biology and Role in Human Health, 2nd Ed. (Hatfield, D. L., Berry, M. J., and Gladyshev, V. N., eds) pp. 90-110, Springer, New York