Effects of anticoccidial and antibiotic growth promoter programs on broiler performance and immune status

Research in Veterinary Science

Volumn 93, Issue 2, 2012, Pages 721-728

  Lee, Kyung Woo ^a   Ho Hong, Yeong ^b   Lee, Sung Hyen ^a   Jang, Seung I ^a   Park, Myeong Seon ^a   Bautista, Daniel A ^c   Donald Ritter, G ^d   Jeong, Wooseog ^e   Jeoung, Hye Young ^e   An, Dong Jun ^e   Lillehoj, Erik P ^f   Lillehoj, Hyun S ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b Chung Ang University   (South Korea)

^c UNIVERSITY OF DELAWARE   (United States)

^d MOUNTAIRE FARMS INC   (United States)

^e Animal Plant and Fisheries Quarantine and Inspection Agency   (South Korea)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Antibiotic growth promoters; Broiler chicken; Coccidiosis control programs; Immunity

Indexed keywords

ANTIBIOTIC AGENT; BACITRACIN METHYLENE DISALICYLATE PLUS ROXARSONE; BIOLOGICAL MARKER; BU1 PROTEIN; CD4 ANTIGEN; CD8 ANTIGEN; COCCIDIOSIS VACCINE; CYTOKINE; DICLAZURIL; INOVOCOX; INTERLEUKIN 10; INTERLEUKIN 17F; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; LIPOPOLYSACCHARIDE INDUCED TUMOR NECROSIS FACTOR ALPHA FACTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTOZOAL VACCINE; SALINOMYCIN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR 1; T LYMPHOCYTE RECEPTOR 2; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH INHIBITOR; VIRGINIAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BROILER; CELL PROLIFERATION; COCCIDIOSIS; CONTROLLED STUDY; EIMERIA; GENE EXPRESSION; GROWTH; IMMUNE RESPONSE; IMMUNE STATUS; INFECTION CONTROL; INTESTINE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; SPLEEN; SPLEEN CELL;

ANIMAL FEED; ANIMALS; ANTI-BACTERIAL AGENTS; CHICK EMBRYO; CHICKENS; COCCIDIOSIS; COCCIDIOSTATS; CYTOKINES; EIMERIA; GENE EXPRESSION REGULATION; MALE; NITRILES; POULTRY DISEASES; PROTOZOAN VACCINES; PYRANS; RNA, MESSENGER; SPLEEN; TRIAZINES;

ANIMALIA; AVES; EIMERIA; GALLUS GALLUS; SPONDIAS PURPUREA;

EID: 84863109986     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2012.01.001     Document Type: Article

References (51)

1. Apajalahti J., Kettunen A., Graham H. Characteristics of the gastrointestinal microbial communities with special reference to the chicken. World's Poultry Science Journal 2004, 60:223-232.
2. Arias V.J., Koutsos E.A. Effects of copper source and level on intestinal physiology and growth of broiler chickens. Poultry Science 2006, 85:999-1007.
3. Atarashi K., Umesaki Y., Honda K. Microbiota influence on T cell subset development. Seminars in Immunology 2011, 23:146-153.
4. Baba T., Yamashita N., Kodama H., Mukamoto M., Asada M., Nakamoto K., Nose Y., Mcgruder E.D. Effect of tylosin tartrate on humoral immune responses in chickens. Journal of Veterinary Medicine B 1998, 45:279-286.
5. Bjerrum L., Engberg R.M., Leser T.D., Jensen B.B., Finster K., Pedersen K. Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture-based techniques. Poultry Science 2006, 85:1151-1164.
6. Chen C.H., Ager L.L., Gartland G.L., Cooper M.D. Identification of a T3/T-cell receptor complex in chickens. Journal of Experimental Medicine 1986, 164:375-386.
7. Chen Y., Chou K., Fuchs E., Havran W., Boismenu R. Protection of the intestinal mucosa by intraepithelial γδ T cells. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:14338-14343.
8. Cheung K.S., Lillehoj H.S., Jenkins M.C. Avian leucocyte common antigens: molecular weight determination and flow cytometric analysis using new monoclonal antibodies. Veterinary Immunology and Immunopathology 1991, 28:259-273.
9. Chichlowski M., Croom J., Mcbride B.W., Daniel L., Davis G., Koci M.D. Direct-fed microbial PrimaLac and salinomycin modulate whole-body and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick. Poultry Science 2007, 86:1100-1106.
10. Cressman M.D., Yu Z., Nelson M.C., Moeller S.J., Lilburn M.S., Zerby H.N. Interrelations between the microbiotas in the litter and in the intestines of commercial broiler chickens. Applied and Environmental Microbiology 2010, 76:6572-6582.
11. Crhanova M., Hradecka H., Faldynova M., Matulova M., Havlickova H., Sisak F., Rychlik I. Immune response of chicken gut to natural colonization by gut microflora and to Salmonella enterica serovar enteritidis infection. Infection and Immunity 2011, 79:2755-2763.
12. Deng X., Li X., Liu P., Yuan S., Zang J., Li S., Piao X. Effect of chito-oligosaccharide supplementation on immunity in broiler chickens. Asian-Australasian Journal of Animal Sciences 2008, 21:1651-1658.
13. Engberg R.M., Hedemann M.S., Leser T.D., Jensen B.B. Effect of zinc bacitracin and salinomycin on intestinal microflora and performance of broilers. Poultry Science 2000, 79:1311-1319.
14. Guban J., Korver D.R., Allison G.E., Tannock G.W. Relationship of dietary antimicrobial drug administration with broiler performance, decreased population levels of Lactobacillus salivarius, and reduced bile salt deconjugation in the ileum of broiler chickens. Poultry Science 2006, 85:2186-2194.
15. Hume M.E., Clemente-Hernández S., Oviedo-Rondón E.O. Effects of feed additives and mixed Eimeria species infection on intestinal microbial ecology of broilers. Poultry Science 2006, 85:2106-2111.
16. Komori H., Meehan T.F., Havran W.L. Epithelial and mucosal γδ T cells. Current Opinion in Immunology 2006, 18:534-538.
17. Lee K.W., Lillehoj H.S. Antimicrobials, gut microbiota and immunity in chickens. Korean Journal of Poultry Science 2011, 38:155-164.
18. Lee Y.K., Mazmanian S.K. Has the microbiota played a critical role in the evolution of the adaptive immune system?. Science 2010, 330:1768-1773.
19. Lee K.W., Lee S.H., Lillehoj H.S., Li G.X., Jang S.I., Babu U.S., Park M.S., Kim D.K., Lillehoj E.P., Neumann A.P., Rehberger T.G., Siragusa G.R. Effects of direct-fed microbials on growth performance, gut morphometry, and immune characteristics in broiler chickens. Poultry Science 2010, 89:203-216.
20. Lee K.W., Lillehoj H.S., Siragusa G.R. Direct-fed microbials and their impact on the intestinal microflora and immune system of chickens. Journal of Poultry Science 2010, 47:106-114.
21. Lee D.N., Lyu S.R., Wang R.C., Weng C.F., Chen B.J. Exhibit differential functions of various antibiotic growth promoters in broiler growth, immune response and gastrointestinal physiology. International Journal of Poultry Science 2011, 10:216-220.
22. Lee K.W., Lillehoj H.S., Jang S.I., Li G.X., Bautista D.A., Phillips K., Ritter D., Lillehoj E.P., Siragusa G.R. Effect of coccidiosis control programs on antibody levels against selected pathogens and serum nitric oxide levels in broiler chickens. Journal of Applied Poultry Research 2011, 20:143-152.
23. Lee K.W., Lillehoj H.S., Jang S.I., Pagès M., Bautista D.A., Pope C.R., Ritter G.D., Lillehoj E.P., Neumann A.P., Siragusa G.R. Effects of in ovo vaccination and anticoccidials on the distribution of Eimeria spp. in poultry litter and serum antibody titers against coccidia in broiler chickens raised on the used litters. Research in Veterinary Science 2011, 93:177-182.
24. Leiva M., Moreno E., Ruiz-Bravo A., Jimenez-Valera M. Immunomodulation by non-absorbable antibiotics given by the intragastric route. International Journal of Antimicrobial Agents 2005, 25:252-255.
25. Li G., Lillehoj H.S., Lee K.W., Lee S.H., Park M.S., Jang S.I., Bauchan G.R., Gay C.G., Ritter G.D., Bautista D.A., Siragusa G.R. Immunopathology and cytokine responses in commercial broiler chickens with gangrenous dermatitis. Avian Pathology 2010, 39:255-264.
26. Lillehoj H.S. Role of T lymphocytes and cytokines in coccidiosis. International Journal of Parasitology 1998, 28:1071-1081.
27. Lillehoj H.S., Cheung K.S. Postnatal development of T lymphocyte subpopulations in the intestinal intraepithelium and lamina propria in chickens. Veterinary Immunology and Immunopathology 1992, 31:347-360.
28. Lillehoj H.S., Kim S., Lillehoj E.P., Bacon L.D. Quantitative differences in Ia antigen expression in the spleens of 15I5-B congenic and inbred chickens as defined by a new monoclonal antibody. Poultry Science 1988, 67:1525-1535.
29. Lillehoj H.S., Lillehoj E.P., Weinstock D., Schat K.A. Functional and biochemical characterizations of avian T lymphocyte antigens identified by monoclonal antibodies. European Journal of Immunology 1988, 18:2059-2065.
30. Lillehoj H.S., Lee S.H., Kim D.K., Park M.S., Tompkins D., Baldwin C., Labresh J., Wagner B. US veterinary immune reagents network. Poultry Science 2010, 89:61.
31. Lu J., Idris U., Harmon B., Hofacre C., Maurer J.J., Lee M.D. Diversity and succession of the intestinal bacterial community of the maturing broiler chicken. Applied and Environmental Microbiology 2003, 69:6816-6824.
32. Morikawa K., Watabe H., Araake M., Morikawa S. Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. Antimicrobial Agents Chemotherapy 1996, 40:1366-1370.
33. Muller P.Y., Janovjak H., Miserez A.R., Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. BioTechniques 2002, 32:1372-1379.
34. Munir K., Muneer M.A., Tiwari A., Masaoud E., Chaudhry R.M. Effects of salinomycin on cell-mediated immunity of broiler chickens against hydropericardium syndrome and Newcastle disease viruses. Poultry Science 2009, 88:86-91.
35. Neumann A.P., Benson J.A., Lee K.W., Ritter G.D., Bautista D.A., Lillehoj H.S., Siragusa G.R. Microbiological effects of Bacillus-based DFM supplementation in broilers raised on used litter from commercial farms with different disease histories. Poultry Science 2011, 90:120.
36. Neumann, A.P., Benson, J.A., Lee, K.W., Ritter, G.D., Bautista, D.A., Lillehoj, H.S., Siragusa, G.R., 2011b. Molecular analysis of broiler chicken gastrointestinal microbial communities associated with common anticoccidial feeding programs. In: International Poultry Scientific Forum. http://www.poultryscience.org.
37. O'hara A.M., Shanahan F. The gut flora as a forgotten organ. EMBO Reports 2006, 7:688-693.
38. Park S.S., Lillehoj H.S., Allen P.C., Park D.W., Fitzcoy S., Bautista D.A., Lillehoj E.P. Immunopathology and cytokine responses in broiler chickens coinfected with Eimeria maxima and Clostridium perfringens with the use of an animal model of necrotic enteritis. Avian Diseases 2008, 52:14-22.
39. Parry S.H., Allen W.D., Porter P. Intestinal immune response to E. coli antigens in the germ-free chickens. Immunology 1977, 32:731-741.
40. Perez V.G., Jacobs C.M., Barnes J., Jenkins M.C., Kuhlenschmidt M.S., Fahey G.C., Parsons C.M., Pettigrew J.E. Effect of corn distillers dried grains with soluble and Eimeria acervulina infection on growth performance and the intestinal microbiota of young chicks. Poultry Science 2011, 90:958-964.
41. Reato G., Cuffini A.M., Tullio V., Mandras N., Roana J., Banche G., Foa R., Carlone N.A. Immunomodulating effect of antimicrobial agents on cytokine production by human polymorphonuclear neutrophils. International Journal of Antimicrobial Agents 2004, 23:150-154.
42. Rhee K., Sethupathi P., Driks A., Lanning D.K., Knight K.L. Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire. Journal of Immunology 2004, 172:1118-1124.
43. Ritter G., Siragusa G., Dunham S., Neumann A. Role of antibiotics on gut microbiota and incidence of gangrenous dermatitis in commercial broilers. Poultry Science 2010, 89:480.
44. Rothwell C.J., Vervelde L., Davison T.F. Identification of chicken Bu-1 alloantigens using the monoclonal antibody AV20. Veterinary Immunology and Immunopathology 1996, 55:225-234.
45. Shanmugasundaram R., Selvaraj R.K. Regulatory T cell properties of chicken CD4+CD25+ cells. Journal of Immunology 2011, 186:1997-2002.
46. Takahashi K., Miura Y., Mizymo T. Antibiotics feeding accelerate functional maturation of intestinal immune-related cells of male broiler chicks after hatch. Journal of Poultry Science 2011, 48:187-193.
47. Torok V.A., Ophel-Keller K., Loo M., Hughes R.J. Application of methods for identifying broiler chicken gut bacterial species linked with increased energy metabolism. Applied and Environmental Microbiology 2008, 74:783-791.
48. Volkova V.V., Bailey R.H., Wills R.W. Salmonella in broiler litter and properties of soil at farm location. PLoS ONE 2009, 4:e6403.
49. Yegani M., Korver D.R. Factors affecting intestinal health in poultry. Poultry Science 2008, 87:2052-2063.
50. Yin Y.-L., Tang Z.R., Sun Z.H., Liu Z.Q., Li T.J., Huang R.L., Ruan Z., Deng Z.Y., Gao B., Chen L.X., Wu G.Y., Kim S.W. Effect of galacto-mannan-oligosaccharides or chitosan supplementation on cytoimmunity and humoral immunity in early-weaned piglets. Asian-Australasian Journal of Animal Sciences 2008, 21:723-731.
51. Yin Y., Lei F., Zhu L., Li S., Wu Z., Zhang R., Gao G.F., Zhu B., Wang X. Exposure of different bacterial inocula to newborn chicken affects gut microbiota development and ileum gene expression. ISME Journal 2010, 4:367-376.