Secreted phospholipase A2-IIA-induced a phenotype of activated microglia in BV-2 cells requires epidermal growth factor receptor transactivation and proHB-EGF shedding

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Martín, Rubén ^a,b   Cordova, Claudia ^a   Nieto, Maria L ^a  

^a University of Valladolid   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

Author keywords

Epidermal growth factor receptor; Microglia; Phagocytosis; Proliferation; Secreted phospholipase A2 IIA

Indexed keywords

CYCLOOXYGENASE 2; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; PTGS2 PROTEIN, MOUSE; SECRETORY PHOSPHOLIPASE A2; SIGNAL PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

ANALYSIS OF VARIANCE; ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECT; FLOW CYTOMETRY; METABOLISM; MICROGLIA; MOUSE; PHAGOCYTOSIS; PHOSPHORYLATION; TIME;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLOW CYTOMETRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROGLIA; PHAGOCYTOSIS; PHOSPHOLIPASES A2, SECRETORY; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84863101801     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-154     Document Type: Article

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