Multiple trophic actions of heparin-binding epidermal growth factor (HB-EGF) in the central nervous system

European Journal of Neuroscience

Volumn 11, Issue 9, 1999, Pages 3236-3246

  Kornblum, Harley I ^a   Zurcher, Shelley D ^a   Werb, Zena ^c   Derynck, Rik ^b,c   Seroogy, Kim B ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Astrocyte; Brain; Epidermal growth factor receptor; Mouse; Neuron; Rat; Stem cell; Transforming growth factor alpha

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NESTIN; NEUROTROPHIC FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN STEM; CELL DIFFERENTIATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MOUSE; NEOCORTEX; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; STEM CELL; THALAMUS;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; EPIDERMAL GROWTH FACTOR; HEPARIN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MICE; NEUROGLIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; STEM CELLS;

EID: 0032862433     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00744.x     Document Type: Article

References (57)

1. Abe, K. & Saito, H. (1992). Protective effect of epidermal growth factor on glutamate neurotoxicity in cultured cerebellar neurons. Neurosci. Res., 14, 117-123.
2. Alexi, T. & Hefti, F. (1993). Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture. Neuroscience, 55, 903-918.
3. Blum, M. (1998) A null mutation in TGFa leads to a reduction in midbrain dopaminergic neurons in the substantia nigra. Nature Neurosci., 1, 374-377.
4. Brewer, G.J., Torricelli, J.R., Evege, E.K. & Price, P.J. (1993). Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J. Neurosci. Res., 35, 567-576.
5. Burrows, R.C., Wancio, D., Levitt, P. & Lillien, L. (1997). Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex. Neuron, 19, 251-267.
6. Casper, D., Roboz, G.J. & Blum, M. (1994). Epidermal growth factor and basic fibroblast growth factor have independent actions on mesencephalic dopamine neurons in culture. J. Neurochem., 62, 2166-2177.
7. Ciccolini, F. & Svendsen, C. (1998) Fibroblast growth factor 2 (FGF-2) promotes acquisition of epidermal growth factor (EGF) responsiveness in mouse striatal precursor cells: identification of neural precursors responding to both EGF and FGF-2. J. Neurosci., 18, 7869-7880.
8. Clarke, S.R., Shetty, A.K., Bradley, J.L. & Turner, D.A. (1994). Reactive astrocytes express the embryonic intermediate neurofilament nestin. Neuroreport, 5, 1885-1888.
9. Craig, C.G., Tropepe, V., Morshead, C.M., Reynolds, B.A., Weiss, S. & van der Kooy, D. (1996). In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J. Neurosci., 16, 2649-2658.
10. Creuzet, C., Loeb, J. & Barbin, G. (1995). Fibroblast growth factors stimulate protein tyrosine phosphorylation and mitogen-activated protein kinase activity in primary cultures of hippocampal neurons. J. Neurochem., 64, 1541-1547.
11. Dalessio, J. & Ashley, R. (1992). Highly sensitive enhanced chemiluminescence immunodetection method for herpes simplex virus type 2 Western immunoblot. J. Clin. Microbiol., 30, 1005-1007.
12. Eagleson, K.L., Ferri, R.T. & Levitt, P. (1996). Complementary distribution of collagen type IV and the epidermal growth factor receptor in the rat embryonic telencephalon. Cereb. Cortex., 6, 540-549.
13. Elenius, K., Paul, S., Allison, G., Sun, J. & Klagsbrun, M. (1997). Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J., 16, 1268-1278.
14. Faber-Elman, A., Solomon, A., Abraham, J.A., Marikovsky, M. & Schwartz, M. (1996). Involvement of wound-associated factors in rat brain astrocyte migratory response to axonal injury: in vitro simulation. J. Clin. Invest., 97, 162-171.
15. Gabay, L., Seger, R. & Shilo, B.Z. (1997). In situ activation pattern of drosophila EGF receptor pathway during development. Science, 277, 1103-1106.
16. Gage, F.H., Coates, P.W., Palmer, T.D., Kuhn, H.G., Fisher, L.J., Suhonen, J.O., Peterson, D.A., Suhr, S.T. & Ray, J. (1995). Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl Acad. Sci. USA, 92, 11879-11883.
17. Gallo, V. & Armstrong, R.C. (1995). Developmental and growth factor-induced regulation of nestin in oligodendrocyte lineage cells. J. Neurosci., 15, 394-406.
18. Gritti, A., Parati, E.A., Cova, L., Frolichsthal, P., Galli, R., Wanke, E., Faravelli, L., Morassutti, D.J., Roisen, R, Nickel, D.D. & Vescovi, A.L. (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J. Neurosci., 16, 1091-1100.
19. Hayase, Y., Higashiyama, S., Sasahara, M., Amano, S., Nakagawa, T., Taniguchi, N. & Hazama, F. (1998). Expression of heparin-binding epidermal growth factor-like growth factor in rat brain. Brain Res., 784, 163-178.
20. Junier, M.P., Hill, D.F., Costa, M.E., Felder, S. & Ojeda, S.R. (1993). Hypothalamic lesions that induce female precocious puberty activate glial expression of the epidermal growth factor receptor gene: differential regulation of alternatively spliced transcripts. J. Neurosci., 13, 703-713.
21. Kilpatrick, T.J. & Bartlett, P.F. (1995). Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF. J. Neurosci., 15, 3653-3661.
22. Komblum, H.I., Chugani, H.T., Tatsukawa, K. & Gall, C.M. (1994). Cerebral hemidecortication alters expression of transforming growth factor alpha mRNA in the neostriatum of developing rats. Brain Res. Mol. Brain Res., 21, 107-114.
23. Kornblum, H.I., Gall, C.M., Seroogy, K.B. & Lauterborn, J.C. (1995). A subpopulation of striatal gabaergic neurons expresses the epidermal growth factor receptor. Neuroscience, 69, 1025-1029.
24. Kornblum, H.I., Hussain, R.J., Bronstein, J.M., Gall, C.M., Lee, D.C. & Seroogy, K.B. (1997). Prenatal ontogeny of the epidermal growth factor receptor and its ligand, transforming growth factor alpha, in the rat brain. J. Comp. Neurol., 380, 243-261.
25. Kornblum, H., Hussain, R., Wiesen, J., Miettinen, P., Zurcher, S., Chow, K., Derynck, R. & Werb, Z. (1998). Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor. J. Neurosci. Res., 53, 697-717.
26. Kornblum, H.I., Raymon, H.K., Morrison, R.S., Cavanaugh, K.P., Bradshaw, R.A. & Leslie, F.M. (1990). Epidermal growth factor and basic fibroblast growth factor: effects on an overlapping population of neocortical neurons in vitro. Brain Res., 535, 255-263.
27. Lai, C. & Lemke, G. (1991). An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system. Neuron, 6, 691-704.
28. Lazar, L.M. & Blum, M. (1992). Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-alpha mRNA in mouse brain by a quantitative nuclease protection assay. J. Neurosci., 12, 1688-1697.
29. Lendahl, U., Zimmerman, L.B. & Mc Kay, R.D. (1990). CNS stem cells express a new class of intermediate filament protein. Cell, 60, 585-595.
30. Leutz, A. & Schachner, M. (1981). Epidermal growth factor stimulates DNA-synthesis of astrocytes in primary cerebellar cultures. Cell Tissue Res., 220, 393-404.
31. Luetteke, N.C., Qiu, T.H., Peiffer, R.L., Oliver, P., Smithies, O. & Lee, D.C. (1993). TGF alpha deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell, 73, 263-278.
32. Miettinen, P.J., Berger, J.E., Meneses, J., Phung, Y., Pedersen, R.A., Werb, Z. & Derynck, R. (1995). Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature, 376, 337-341.
33. Morrison, R.S. & de Vellis, J. (1981). Growth of purified astrocytes in a chemically defined medium. Proc. Natl Acad. Sci. USA, 78, 7205-7209.
34. Morrison, R.S., Kornblum, H.I., Leslie, F.M. & Bradshaw, R.A. (1987). Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor. Science, 238, 72-75.
35. Nakagawa, T., Sasahara, M., Hayase, Y., Haneda, M., Yasuda, H., Kikkawa, R., Higashiyama, S. & Hazama, F. (1998). Neuronal and glial expression of heparin-binding EGF-like growth factor in central nervous system of prenatal and early-postnatal rat. Dev. Brain Res., 108, 263-272.
36. Opanashuk, L., Mark, R., Porter, J., Damm, D., Mattson, M. & Seroogy, K. (1999). Heparin-binding EGF-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action. J. Neurosci., 19, 133-146.
37. Opanashuk, L.A., Numan, S. & Seroogy, K.B. (1995). Expression of heparin - binding epidermal growth factor (HB-EGF) mRNA in rat brain. Soc. Neurosci. Abstr., 21, 2011.
38. Pinkas-Kramarski, R., Eilam, R., Alroy, I., Levkowitz, G., Lonai, P. & Yarden, Y. (1997). Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation. Oncogene, 15, 2803-2815.
39. Plowman, G.D., Culouscou, J.M., Whitney, G.S., Green, J.M., Carlton, G.W., Foy, L., Neubauer, M.G. & Shoyab, M. (1993). Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family. Proc. Natl Acad. Sci. USA, 90, 1746-1750.
40. Qian, X., LeVea, C.M., Freeman, J.K., Dougall, W.C. & Greene, M.I. (1994). Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation. Proc. Natl Acad. Sci. USA, 91, 1500-1504.
41. Raabe, T.D., Suy, S., Welcher, A. & DeVries, G.H. (1997). Effect of neu differentiation factor isoforms on neonatal oligodendrocyte function. J. Neurosci. Res., 50, 755-768.
42. Reynolds, B.A. & Weiss, S. (1992). Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science, 255, 1707-1710.
43. Riese, D.J., Kim, E.D., Elenius, K., Buckley, S., Klagsbrun, M.. Plowman, G.D. & Stern, D.F. (1996). The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4. J. Biol. Chem., 271, 20047-20052.
44. Seroogy, K.B., Gall, C.M., Lee, D.C. & Kornblum, H.I. (1995). Proliferate zones of postnatal rat brain express epidermal growth factor receptor mRNA. Brain Res., 670, 157-164.
45. Seroogy, K.B., Han, V.K. & Lee, D.C. (1991). Regional expression of transforming growth factor-alpha mRNA in the rat central nervous system. Neurosci. Lett., 125, 241-245.
46. Seroogy, K.B., Lundgren, K.H., Lee, D.C., Guthrie, K.M. & Gall, C.M. (1993). Cellular localization of transforming growth factor-alpha mRNA in rat forebrain. J. Neurochem., 60, 1777-1782.
47. Seroogy, K.B., Numan, S., Gall, C.M., Lee, D.C. & Kornblum, H.I. (1994). Expression of EGF receptor mRNA in rat nigrostriatal system. Neuroreport, 6, 105-108.
48. Seroogy, K., Opanashuk, L., Davis, B. & Kornblum, H. (1996). Amphiregulin, an EGF-related growth factor, is expressed in discrete regions of mouse nervous system. Soc. Neurosci. Abstr., 22, 300.
49. Seroogy, K., Yurek, D., Lundgren, K., Korfhage, J., Gash, D., Cass, W. & Kornblum, H. (1998). Neuregulin receptor expression and regulation in rodent and monkey niarostriatal system. Soc. Neurosci. Abstr., 24, 1785.
50. Sibilia, M., Steinbach, J.P., Stingl, L., Aguzzi, A. & Wagner, E.F. (1998). A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J., 17, 719-731.
51. Traverse, S., Seedorf, K., Paterson, H., Marshall, C.J., Cohen, P. & Ullrich, A. (1994). EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor. Curr. Biol., 4, 694-701.
52. Tropepe, V., Craig. C.G., Morshead, C.M. & van der Kooy, D. (1997). Transforming growth factor-null and senescent mice show decreased Neural progenitor cell proliferation in the forebrain subependyma. J. Neurosci., 17, 7850-7859.
53. Vaines, K. & Brandtzaeg, P. (1984). Paired indirect immunoenzyme staining with primary antibodies from the same species. Application of horseradish peroxidase and alkaline phosphatase as sequential labels. Histochem. J., 16, 477-487.
54. Vescovi, A.L., Reynolds, B.A., Fraser, D.D. & Weiss, S. (1993). bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron, 11, 951-966.
55. Vicario-Abejon, C., Johe, K.K., Hazel, T.G., Collazo, D. & Mc Kay, R.D. (1995). Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron, 15, 105-114.
56. Weickert, C.S. & Blum, M. (1995). Striatal TGF-alpha: postnatal developmental expression and evidence for a role in proliferation of subependymal cells. Dev. Brain Res., 86, 203-216.
57. Wilcox, J.N. & Derynck, R. (1988). Localization of cells synthesizing transforming growth factor-alpha mRNA in the mouse brain. J. Neurosci., 8, 1901-1904.