Resistance to acetaminophen-induced hepatotoxicity in glutathione S-transferase Mu 1-null mice

Journal of Toxicological Sciences

Volumn 37, Issue 3, 2012, Pages 595-605

  Arakawa, Shingo ^a   Maejima, Takanori ^a   Fujimoto, Kazunori ^a   Yamaguchi, Takashi ^a   Yagi, Masae ^a   Sugiura, Tomomi ^a   Atsumi, Ryo ^a   Yamazoe, Yasushi ^b  

^a DAIICHI SANKYO CO   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Acetaminophen; c jun N terminal kinase; Glutathione; Glutathione S transferases Mu 1; Hepatotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTATHIONE TRANSFERASE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; STRESS ACTIVATED PROTEIN KINASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; DISEASE RESISTANCE; ENZYME PHOSPHORYLATION; FEMALE; HISTOPATHOLOGY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; WESTERN BLOTTING;

MUS;

EID: 84863095831     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.595     Document Type: Article

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