Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Sawitzky, Mandy ^a   Zeissler, Anja ^a   Langhammer, Martina ^a   Bielohuby, Maximilian ^b   Stock, Peggy ^c   Hammon, Harald M ^a   Görs, Solvig ^a   Metges, Cornelia C ^a   Stoehr, Barbara J M ^b   Bidlingmaier, Martin ^b   Fromm Dornieden, Carolin ^d   Baumgartner, Bernhard G ^d   Christ, Bruno ^c   Brenig, Bertram ^d   Binder, Gerhard ^e   Metzger, Friedrich ^f   Renne, Ulla ^a   Hoeflich, Andreas ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^d Institute of Veterinary Medicine   (Germany)

^e UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^f F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GLYCOGEN; GLYCOGEN SYNTHASE KINASE 3BETA; INITIATION FACTOR 2ALPHA; INSULIN; INTEGRIN LINKED KINASE; MYOSTATIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN S6; RNA; S6 KINASE; SOMATOMEDIN B; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

ADULT ANIMAL; AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; COEVOLUTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; MALE; MOUSE; MUSCLE MASS; NONHUMAN; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; WESTERN BLOTTING;

ANIMALS; BODY WEIGHT; ENZYME ACTIVATION; EVOLUTION, MOLECULAR; FEMALE; GLYCOGEN; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MICE; MODELS, BIOLOGICAL; MUSCLES; ORGAN SIZE; PHENOTYPE; PROTEIN BIOSYNTHESIS; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TISSUE EXTRACTS;

EUKARYOTA; MUS;

EID: 84863094071     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0039711     Document Type: Article

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