In vitro selection and characterization of a novel Zn(II)-dependent phosphorothiolate thiolesterase ribozyme

Biochemistry

Volumn 51, Issue 1, 2012, Pages 496-510

  Wang, Tzu Pin ^a   Su, Yu Chih ^a   Chen, Yi ^a   Liou, Yi Ming ^a   Lin, Kun Liang ^a   Wang, Eng Chi ^a   Hwang, Long Chih ^a   Wang, Yun Ming ^b   Chen, Yen Hsu ^a,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL RNA; IN-VITRO; ORDERS OF MAGNITUDE; RATE ENHANCEMENT; RIBOZYMES; SECONDARY STRUCTURES; UNCATALYZED REACTIONS;

CATALYSIS; HYDROLYSIS; RNA; ZINC COMPOUNDS;

ZINC;

MAGNESIUM ION; PHOSPHOROTHIOLATE THIOLESTERASE; RIBOZYME; THIOL ESTER HYDROLASE; TW17 RIBOZYME; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; CATALYSIS; CATALYST; ENZYME STRUCTURE; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REACTION TIME; STRUCTURE ANALYSIS; TRANS ISOMER;

5'-GUANYLIC ACID; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BIOTIN; CARBON-NITROGEN LIGASES; CATALYSIS; MUTAGENESIS, SITE-DIRECTED; NADH, NADPH OXIDOREDUCTASES; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; THIOLESTER HYDROLASES; THIONUCLEOTIDES; TRANS-ACTIVATORS; ZINC;

EID: 84863069633     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201585d     Document Type: Article

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