Zinc-dependent cleavage in the catalytic core of the hammerhead ribozyme: Evidence for a pH-dependent conformational change

Nucleic Acids Research

Volumn 31, Issue 10, 2003, Pages 2595-2600

  Borda, Emily J ^a   Markley, John C ^a   Sigurdsson, Snorri Th ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE; RIBOZYME; ZINC ION; DIVALENT CATION; MAGNESIUM; MONOVALENT CATION; OLIGORIBONUCLEOTIDE; ZINC;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; NONHUMAN; PH; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA CLEAVAGE; CHEMISTRY; CONFORMATION; DRUG EFFECT; DRUG INTERACTION; ENZYME SPECIFICITY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; BINDING SITES; CATALYSIS; CATIONS, DIVALENT; CATIONS, MONOVALENT; DRUG INTERACTIONS; HYDROGEN-ION CONCENTRATION; MAGNESIUM; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; ZINC;

EID: 0038043313     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg349     Document Type: Article

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