Hepatoprotective effects of total triterpenoids and total flavonoids from Vitis vinifera L against immunological liver injury in mice

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Liu, Tao ^a   Zhao, Jun ^b   Ma, Long ^a   Ding, Yusong ^c   Su, Deqi ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

^b Institute of Materia Medica of Xinjiang   (China)

^c SHIHEZI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BACTERIUM LIPOPOLYSACCHARIDE; BCG VACCINE; BIPHENYL DICARBOXYLATE; FLAVONOID; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TRITERPENOID; UNCLASSIFIED DRUG; VITIS VINIFERA EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; EXPERIMENTAL MODEL; GRAPE; IMMUNOREGULATION; LIVER HOMOGENATE; LIVER INJURY; LIVER LEVEL; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH2 CELL;

EID: 84863052092     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/969386     Document Type: Article

References (31)

1. Lavanchy D., Hepatitis B virus epidemiology, disease burden, treatment, arid current and emerging prevention and control measures Journal of Viral Hepatitis 2004 11 2 97 107 (Pubitemid 38365759)
2. Moriyama T., Guilhot S., Klopchin K., Moss B., Pinkert C. A., Palmiter R. D., Brinster R. L., Kanagawa O., Chisari F. V., Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice Science 1990 248 4953 528 530
3. Koziel M. J., Cytokines in viral hepatitis Seminars in Liver Disease 1999 19 2 157 169
4. Fung J., Lai C. L., Yuen M. F., Overcoming the problem of chronic hepatitis B Drug Discovery Today: Therapeutic Strategies 2006 3 2 197 202 (Pubitemid 44173705)
5. Bombardelli E., Morazzoni P., Vitis vinifera L Fitoterapia 1995 66 4 291 317
6. Liu Y. M., Pharmacography of Uighur 1999 Urumuqi, China Xinjiang Science Technology Hygiene Publishing House
7. Orbn N., Kozk I. O., Drvucz M., Kiss A., LC-MS method development to evaluate major triterpenes in skins and cuticular waxes of grape berries International Journal of Food Science and Technology 2009 44 4 869 873
8. Xia E. Q., Deng G. F., Guo Y. J., Li H. B., Biological activities of polyphenols from grapes International Journal of Molecular Sciences 2010 11 2 622 646
9. Kim D. J., Lee J. S., Kim K. J., Macrophage stimulating polysaccharide purified from peels of Grape (Vitis labrusca) Food Science and Biotechnology 2010 19 2 479 486
10. Christine D. W., Grape products and oral health The Journal of Nutrition Supplement: Grapes and Health 2009 139 9 1818S 1823S
11. Liu T., Zhao J., Li H. B., Ma L., Evaluation on anti-hepatitis viral activity of vitis vinifer L Molecules 2010 15 10 7415 7421
12. Liu T., Ma L., Zhao J., Ma Q., Protective effects of triterpenoids from Vitis vinifera l L. on immunological liver injury in vitro Journal of Xinjiang Medical University 2007 30 1222 1225
13. Zuhal G., Nurcan K., Cavit K., Yusuf K., Omur L. D., Chemical constituents of Galium tortumense Turkish Journal of Chemistry 2006 30 4 515 523
14. Lee J. H., Ku C. H., Baek N. I., Kim S. H., Park H. W., Kim D. K., Phytochemical constituents from Diodia teres Archives of Pharmacal Research 2004 27 1 40 43 (Pubitemid 43154538)
15. Mahmoud I. I., Marzouk M. S. A., Moharram F. A., El-Gindi M. R., Hassan A. M., Acylated flavonol glycosides from Eugenia jambolana leaves Phytochemistry 2001 58 8 1231 1239
16. Tian J. K., Zou Z. M., Xu L. Z., Studies on chemical constituents of Lysimachia davurica Chinese Traditional and Herbal Drugs 2001 32 967 969
17. Rena K., Palida A., Zhang X. Y., Studies on the chemical constituents from Xinjiang Punica granatum Zhong Yao Cai 2009 32 3 363 365
18. Thorsten M., Solveigh S., Dietmar R. K., Berardini N., Conrad J., Beifuss U., Carle R., Schieber A., Isolation of hydroxycinnamoyltartaric acids from grape pomace by high-speed counter-current chromatography Journal of Chromatography A 2006 1128 1-2 61 67 (Pubitemid 44292730)
19. Wang G. S., Liu G. T., Role of nitric oxide in immunological liver damage in mice Biochemical Pharmacology 1995 49 9 1277 1281
20. Yajima T., Nishimura H., Saito K., Kuwano H., Yoshikai Y., Overexpression of interleukin-15 increases susceptibility to lipopolysaccharide-induced liver injury in mice primed with Mycobacterium bovis bacillus Calmette-Guerin Infection and Immunity 2004 72 7 3855 3862 (Pubitemid 38821898)
21. Shimizu I., Ma Y. R., Mizobuchi Y., Liu F., Miura T., Naka Y., Yasuda M., Shiba M., Horie T., Amagaya S., Kawada N., Hori H., Ito S., Effects of Sho-saiko-to, a Japanese herbal medicine, on hepatic fibrosis in rats Hepatology 1999 29 1 149 160 (Pubitemid 29023997)
22. Polavarapu R., Spitz D. R., Sim J. E., Follansbee M. H., Oberley L. W., Rahemtulla A., Nanji A. A., Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil Hepatology 1998 27 5 1317 1323 (Pubitemid 28227859)
23. Kim Y. M., Son K., A nitric oxide production bioassay for interferon- Journal of Immunological Methods 1996 198 2 203 209 (Pubitemid 26378878)
24. Laskin D. L., Rodriguez D. V. M., Heck D. E., Hwang S. M., Ohnishi S. T., Durham S. K., Goller N. L., Laskin J. D., Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducible nitric oxide synthase gene expression Hepatology 1995 22 1 223 234
25. Arai M., Mochida S., Ohno A., Ogata I., Fujiwara K., Sinusoidal endothelial cell damage by activated macrophages in rat liver necrosis Gastroenterology 1993 104 5 1466 1471 (Pubitemid 23235421)
26. Mochida S., Arai M., Ohno A., Fujiwara K., Deranged blood coagulation equilibrium as a factor of massive liver necrosis following endotoxin administration in partially hepatectomized rats Hepatology 1999 29 5 1532 1540 (Pubitemid 29211057)
27. Ando K., Hiroishi K., Kaneko T., Moriyama T., Muto Y., Kayagaki N., Yagita H., Okumura K., Imawari M., Perforin, Fas/Fas ligand, and TNF- pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL Journal of Immunology 1997 158 11 5283 5291 (Pubitemid 127681233)
28. Mimura S., Mochida S., Inao M., Matsui A., Nagoshi S., Yoshimoto T., Fujiwara K., Massive liver necrosis after provocation of imbalance between Th1 and Th2 immune reactions in osteopontin transgenic mice Journal of Gastroenterology 2004 39 9 867 872 (Pubitemid 39409668)
29. Thompson C. B., Apoptosis in the pathogenesis and treatment of disease Science 1995 267 5203 1456 1462
30. Kroemer G., The proto-oncogene Bcl-2 and its role in regulating apoptosis Nature Medicine 1997 3 6 614 620 (Pubitemid 27264969)
31. Hugh J. M. B., Gabriel G. G., Bax. The pro-apoptotic Bcl-2 family member, Bax. The International Journal of Biochemistry Cell Biology 1998 30 647 650