IL-2-engineered nano-APC effectively activates viral antigen-mediated T cell responses from chronic hepatitis B virus-infected patients

Journal of Immunology

Volumn 188, Issue 3, 2012, Pages 1534-1543

  Liu, Mengya ^a,b   Miao, Tizong ^b   Zhu, Haoxiang ^c   Symonds, Alistair L J ^b   Li, Li ^b   Schurich, Anna ^d   Maini, Mala K ^d   Zhang, Jiming ^c   Kennedy, Patrick T F ^b   Li, Suling ^a   Wang, Ping ^b  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; GAMMA INTERFERON; HEPATITIS B(E) ANTIGEN; HLA A ANTIGEN; HLA A2 ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR; TAPASIN;

ADOLESCENT; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOCYTOSIS; FEMALE; HEPATITIS B; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; IMMUNOSTIMULATION; MAJOR CLINICAL STUDY; MALE; MOUSE; NANOENGINEERING; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS ACTIVATION; VIRUS LOAD;

ANTIGEN PRESENTATION; ANTIGENS, VIRAL; HEPATITIS B, CHRONIC; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; NANOPARTICLES; PROTEIN ENGINEERING; T-LYMPHOCYTES;

EID: 84863050420     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102709     Document Type: Article

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