A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production

Molecular Medicine Reports

Volumn 5, Issue 3, 2012, Pages 739-744

  Zhang, Xie ^a   Zhang, Han Qing ^a   Zhu, Guang Hui ^a   Wang, Yu Huang ^a   Yu, Xi Chong ^a   Zhu, Xin Bo ^a   Liang, Guang ^a   Xiao, Jian ^a   Li, Xiao Kun ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b JILIN AGRICULTURAL UNIVERSITY   (China)

Author keywords

Curcumin analogues; Endoplasmic reticulum stress; Ovarian cancer; Reactive oxygen species

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; B 19; CARBONYL DERIVATIVE; CURCUMIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; METHYL THIAZOLYL TETRAZOLIUM; REACTIVE OXYGEN METABOLITE; TETRAZOLIUM; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NITROBLUE TETRAZOLIUM TEST; OVARY CARCINOMA; PROTEIN EXPRESSION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 4; APOPTOSIS; CARCINOMA; CELL LINE, TUMOR; CURCUMIN; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMANS; KETONES; OVARIAN NEOPLASMS; REACTIVE OXYGEN SPECIES; RECEPTORS, G-PROTEIN-COUPLED; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS;

EID: 84863024153     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.700     Document Type: Article

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