3′, 4′-Dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells

Toxicological Sciences

Volumn 58, Issue 2, 2000, Pages 235-242

  Lee, J E ^a   Safe, S ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

3 ,4 dimethoxyflavone; AhR; Antagonist; Breast cancer cells

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3',4' DIMETHOXYFLAVONE; AROMATIC HYDROCARBON; AROMATIC HYDROCARBON RECEPTOR; CELL EXTRACT; CYTOCHROME P450 1A1; ESTRADIOL; ETHOXYRESORUFIN; ETHOXYRESORUFIN DEETHYLASE; FLAVONE DERIVATIVE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL NUCLEUS; CELL STRAIN MCF 7; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE CONSTRUCT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CYTOSOL; NONHUMAN; RAT; RECEPTOR BINDING; RECEPTOR BLOCKING; REPORTER GENE; TRANSACTIVATION; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME INDUCTION; FEMALE; MALE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

ANIMALS; BREAST NEOPLASMS; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; FEMALE; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ARYL HYDROCARBON; STRUCTURE-ACTIVITY RELATIONSHIP; TETRACHLORODIBENZODIOXIN; TRANS-ACTIVATION (GENETICS);

EID: 0034352888     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/58.2.235     Document Type: Article

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