Zebrafish models for dyskeratosis congenita reveal critical roles of p53 activation contributing to hematopoietic defects through RNA processing

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Zhang, Ying ^a,b,c   Morimoto, Kenji ^c   Danilova, Nadia ^c   Zhang, Bo ^b   Lin, Shuo ^a,c  

^a PEKING UNIVERSITY   (China)

^b Peking University   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYSKERIN; PROTEIN P53; RIBOSOME RNA; TELOMERASE; CELL CYCLE PROTEIN; DKC1 PROTEIN, ZEBRAFISH; NOLA1 PROTEIN, ZEBRAFISH; NUCLEAR PROTEIN; SMALL NUCLEOLAR RIBONUCLEOPROTEIN; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DEPRESSION; CONTROLLED STUDY; DISEASE ASSOCIATION; DYSKERATOSIS CONGENITA; DYSKERATOSIS CONGENITA 1 GENE; EMBRYO; ENZYME ACTIVITY; ENZYME MECHANISM; EXPERIMENTAL MODEL; GENE; NOLA 1 GENE; NONHUMAN; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA PROCESSING; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; DISEASE MODEL; EMBRYO DEVELOPMENT; GENETICS; HEMATOLOGIC DISEASE; HEMATOPOIETIC SYSTEM; METABOLISM; MULTIPLE MALFORMATION SYNDROME; PATHOLOGY; PHYSIOLOGY; TRANSGENIC ANIMAL;

DANIO RERIO;

ABNORMALITIES, MULTIPLE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL CYCLE PROTEINS; DISEASE MODELS, ANIMAL; DYSKERATOSIS CONGENITA; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; HEMATOLOGIC DISEASES; HEMATOPOIETIC SYSTEM; NUCLEAR PROTEINS; RIBONUCLEOPROTEINS, SMALL NUCLEOLAR; RNA PROCESSING, POST-TRANSCRIPTIONAL; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84863012382     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030188     Document Type: Article

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