-
1
-
-
0035674996
-
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: Identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE)
-
Argani P, Iacobuzio-Donahue C, Ryu B, Rosty C, Goggins M, Wilentz RE, Murugesan SR, Leach SD, Jaffee E, Yeo CJ, Cameron JL, Kern SE, Hruban RH (2001) Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res 7: 3862-3868 (Pubitemid 34044602)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.12
, pp. 3862-3868
-
-
Argani, P.1
Iacobuzio-Donahue, C.2
Ryu, B.3
Rosty, C.4
Goggins, M.5
Wilentz, R.E.6
Murugesan, S.R.7
Leach, S.D.8
Jaffee, E.9
Yeo, C.J.10
Cameron, J.L.11
Kern, S.E.12
Hruban, R.H.13
-
2
-
-
84855357265
-
Mesothelin expression correlates with prolonged patient survival in gastric cancer
-
Baba K, Ishigami S, Arigami T, Uenosono Y, Okumura H, Matsumoto M, Kurahara H, Uchikado Y, Kita Y, Kijima Y, Kitazono M, Shinchi H, Ueno S, Natsugoe S (2011) Mesothelin expression correlates with prolonged patient survival in gastric cancer. J Surg Oncol 105: 195-199
-
(2011)
J Surg Oncol
, vol.105
, pp. 195-199
-
-
Baba, K.1
Ishigami, S.2
Arigami, T.3
Uenosono, Y.4
Okumura, H.5
Matsumoto, M.6
Kurahara, H.7
Uchikado, Y.8
Kita, Y.9
Kijima, Y.10
Kitazono, M.11
Shinchi, H.12
Ueno, S.13
Natsugoe, S.14
-
3
-
-
56449108335
-
Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin e via activation of signal transducer and activator of transcription protein 3
-
Bharadwaj U, Li M, Chen C, Yao Q (2008) Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3. Mol Cancer Res 6: 1755-1765
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1755-1765
-
-
Bharadwaj, U.1
Li, M.2
Chen, C.3
Yao, Q.4
-
4
-
-
80052143814
-
Mesothelin confers pancreatic cancer cell resistance to TNF-alpha-induced apoptosis through Akt/PI3K/NF-kappaB activation and IL-6/Mcl-1 overexpression
-
Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q (2011a) Mesothelin confers pancreatic cancer cell resistance to TNF-alpha-induced apoptosis through Akt/PI3K/NF-kappaB activation and IL-6/Mcl-1 overexpression. Mol Cancer 10: 106
-
(2011)
Mol Cancer
, vol.10
, pp. 106
-
-
Bharadwaj, U.1
Marin-Muller, C.2
Li, M.3
Chen, C.4
Yao, Q.5
-
5
-
-
79960068710
-
Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation
-
Bharadwaj U, Marin-Muller C, Li M, Chen C, Yao Q (2011b) Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation. Carcinogenesis 32: 1013-1024
-
(2011)
Carcinogenesis
, vol.32
, pp. 1013-1024
-
-
Bharadwaj, U.1
Marin-Muller, C.2
Li, M.3
Chen, C.4
Yao, Q.5
-
6
-
-
0030069718
-
Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers
-
DOI 10.1073/pnas.93.1.136
-
Chang K, Pastan I (1996) Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc Natl Acad Sci USA 93: 136-140 (Pubitemid 26041483)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.1
, pp. 136-140
-
-
Chang, K.1
Pastan, I.2
-
7
-
-
0026503664
-
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium
-
Chang K, Pastan I, Willingham MC (1992) Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium. Int J Cancer 50: 373-381
-
(1992)
Int J Cancer
, vol.50
, pp. 373-381
-
-
Chang, K.1
Pastan, I.2
Willingham, M.C.3
-
8
-
-
73149108613
-
Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway
-
Chang MC, Chen CA, Hsieh CY, Lee CN, Su YN, Hu YH, Cheng WF (2009) Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway. Biochem J 424: 449-458
-
(2009)
Biochem J
, vol.424
, pp. 449-458
-
-
Chang, M.C.1
Chen, C.A.2
Hsieh, C.Y.3
Lee, C.N.4
Su, Y.N.5
Hu, Y.H.6
Cheng, W.F.7
-
9
-
-
63949085839
-
High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
-
Cheng WF, Huang CY, Chang MC, Hu YH, Chiang YC, Chen YL, Hsieh CY, Chen CA (2009) High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma. Br J Cancer 100: 1144-1153
-
(2009)
Br J Cancer
, vol.100
, pp. 1144-1153
-
-
Cheng, W.F.1
Huang, C.Y.2
Chang, M.C.3
Hu, Y.H.4
Chiang, Y.C.5
Chen, Y.L.6
Hsieh, C.Y.7
Chen, C.A.8
-
10
-
-
80054861821
-
Co-expression of mesothelin and CA125 correlates with unfavorable patient outcome in pancreatic ductal adenocarcinoma
-
Einama T, Kamachi H, Nishihara H, Homma S, Kanno H, Takahashi K, Sasaki A, Tahara M, Okada K, Muraoka S, Kamiyama T, Matsuno Y, Ozaki M, Todo S (2011) Co-expression of mesothelin and CA125 correlates with unfavorable patient outcome in pancreatic ductal adenocarcinoma. Pancreas 40: 1276-1282
-
(2011)
Pancreas
, vol.40
, pp. 1276-1282
-
-
Einama, T.1
Kamachi, H.2
Nishihara, H.3
Homma, S.4
Kanno, H.5
Takahashi, K.6
Sasaki, A.7
Tahara, M.8
Okada, K.9
Muraoka, S.10
Kamiyama, T.11
Matsuno, Y.12
Ozaki, M.13
Todo, S.14
-
11
-
-
3042621639
-
Mesothelin: A new target for immunotherapy
-
DOI 10.1158/1078-0432.CCR-03-0801
-
Hassan R, Bera T, Pastan I (2004) Mesothelin: a new target for immunotherapy. Clin Cancer Res 10: 3937-3942 (Pubitemid 38812466)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.12
, pp. 3937-3942
-
-
Hassan, R.1
Bera, T.2
Pastan, I.3
-
12
-
-
37249025607
-
Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts
-
DOI 10.1158/1078-0432.CCR-07-1592
-
Hassan R, Broaddus VC, Wilson S, Liewehr DJ, Zhang J (2007a) Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts. Clin Cancer Res 13: 7166-7171 (Pubitemid 350276903)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.23
, pp. 7166-7171
-
-
Hassan, R.1
Broaddus, V.C.2
Wilson, S.3
Liewehr, D.J.4
Zhang, J.5
-
13
-
-
34548858453
-
Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
-
DOI 10.1158/1078-0432.CCR-07-0869
-
Hassan R, Bullock S, Premkumar A, Kreitman RJ, Kindler H, Willingham MC, Pastan I (2007b) Phase I study of SS1P, a recombinant antimesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin Cancer Res 13: 5144-5149 (Pubitemid 47502082)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.17
, pp. 5144-5149
-
-
Hassan, R.1
Bullock, S.2
Premkumar, A.3
Kreitman, R.J.4
Kindler, H.5
Willingham, M.C.6
Pastan, I.7
-
14
-
-
37449006756
-
Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin
-
Hassan R, Ebel W, Routhier EL, Patel R, Kline JB, Zhang J, Chao Q, Jacob S, Turchin H, Gibbs L, Phillips MD, Mudali S, Iacobuzio-Donahue C, Jaffee EM, Moreno M, Pastan I, Sass PM, Nicolaides NC, Grasso L (2007c) Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin. Cancer Immun 7: 20
-
(2007)
Cancer Immun
, vol.7
, pp. 20
-
-
Hassan, R.1
Ebel, W.2
Routhier, E.L.3
Patel, R.4
Kline, J.B.5
Zhang, J.6
Chao, Q.7
Jacob, S.8
Turchin, H.9
Gibbs, L.10
Phillips, M.D.11
Mudali, S.12
Iacobuzio-Donahue, C.13
Jaffee, E.M.14
Moreno, M.15
Pastan, I.16
Sass, P.M.17
Nicolaides, N.C.18
Grasso, L.19
-
15
-
-
37249038187
-
Mesothelin targeted cancer immunotherapy
-
DOI 10.1016/j.ejca.2007.08.028, PII S095980490700696X
-
Hassan R, Ho M (2008) Mesothelin targeted cancer immunotherapy. Eur J Cancer 44: 46-53 (Pubitemid 350262830)
-
(2008)
European Journal of Cancer
, vol.44
, Issue.1
, pp. 46-53
-
-
Hassan, R.1
Ho, M.2
-
16
-
-
23844542990
-
Localization of mesothelin in epithelial ovarian cancer
-
DOI 10.1097/01.pai.00000141545.36485.d6
-
Hassan R, Kreitman RJ, Pastan I, Willingham MC (2005a) Localization of mesothelin in epithelial ovarian cancer. Appl Immunohistochem Mol Morphol 13: 243-247 (Pubitemid 41209017)
-
(2005)
Applied Immunohistochemistry and Molecular Morphology
, vol.13
, Issue.3
, pp. 243-247
-
-
Hassan, R.1
Kreitman, R.J.2
Pastan, I.3
Willingham, M.C.4
-
17
-
-
28444437055
-
Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis
-
DOI 10.1309/F1B6-4CL7-H8VJ-KEAF
-
Hassan R, Laszik ZG, Lerner M, Raffeld M, Postier R, Brackett D (2005b) Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis. Am J Clin Pathol 124: 838-845 (Pubitemid 41740183)
-
(2005)
American Journal of Clinical Pathology
, vol.124
, Issue.6
, pp. 838-845
-
-
Hassan, R.1
Laszik, Z.G.2
Lerner, M.3
Raffeld, M.4
Postier, R.5
Brackett, D.6
-
18
-
-
77952551039
-
Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapy
-
Hassan R, Schweizer C, Lu KF, Schuler B, Remaley AT, Weil SC, Pastan I (2010) Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: implications for cancer therapy. Lung Cancer 68: 455-459
-
(2010)
Lung Cancer
, vol.68
, pp. 455-459
-
-
Hassan, R.1
Schweizer, C.2
Lu, K.F.3
Schuler, B.4
Remaley, A.T.5
Weil, S.C.6
Pastan, I.7
-
19
-
-
77957263361
-
Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo
-
Inami K, Abe M, Takeda K, Hagiwara Y, Maeda M, Segawa T, Suyama M, Watanabe S, Hino O (2009) Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo. Cancer Sci 101: 969-974
-
(2009)
Cancer Sci
, vol.101
, pp. 969-974
-
-
Inami, K.1
Abe, M.2
Takeda, K.3
Hagiwara, Y.4
Maeda, M.5
Segawa, T.6
Suyama, M.7
Watanabe, S.8
Hino, O.9
-
20
-
-
59249092574
-
Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma
-
Inami K, Kajino K, Abe M, Hagiwara Y, Maeda M, Suyama M, Watanabe S, Hino O (2008) Secretion of N-ERC/mesothelin and expression of C-ERC/mesothelin in human pancreatic ductal carcinoma. Oncol Rep 20: 1375-1380
-
(2008)
Oncol Rep
, vol.20
, pp. 1375-1380
-
-
Inami, K.1
Kajino, K.2
Abe, M.3
Hagiwara, Y.4
Maeda, M.5
Suyama, M.6
Watanabe, S.7
Hino, O.8
-
22
-
-
39749173738
-
Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer
-
DOI 10.1158/1535-7163.MCT-07-0483
-
Li M, Bharadwaj U, Zhang R, Zhang S, Mu H, Fisher WE, Brunicardi FC, Chen C, Yao Q (2008) Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer. Mol Cancer Ther 7: 286-296 (Pubitemid 351302523)
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.2
, pp. 286-296
-
-
Li, M.1
Bharadwaj, U.2
Zhang, R.3
Zhang, S.4
Mu, H.5
Fisher, W.E.6
Brunicardi, F.C.7
Chen, C.8
Yao, Q.9
-
23
-
-
0142169984
-
Application of Mesothelin Immunostaining in Tumor Diagnosis
-
DOI 10.1097/00000478-200311000-00003
-
Ordonez NG (2003a) Application of mesothelin immunostaining in tumor diagnosis. Am J Surg Pathol 27: 1418-1428 (Pubitemid 37315193)
-
(2003)
American Journal of Surgical Pathology
, vol.27
, Issue.11
, pp. 1418-1428
-
-
Ordonez, N.G.1
-
24
-
-
0037341494
-
Value of mesothelin immunostaining in the diagnosis of mesothelioma
-
DOI 10.1097/01.MP.0000056981.16578.C3
-
Ordonez NG (2003b) Value of mesothelin immunostaining in the diagnosis of mesothelioma. Mod Pathol 16: 192-197 (Pubitemid 36337423)
-
(2003)
Modern Pathology
, vol.16
, Issue.3
, pp. 192-197
-
-
Ordonez, N.G.1
-
25
-
-
12144288836
-
Analysis of Novel Tumor Markers in Pancreatic and Biliary Carcinomas using Tissue Microarrays
-
DOI 10.1016/j.humpath.2003.10.012
-
Swierczynski SL, Maitra A, Abraham SC, Iacobuzio-Donahue CA, Ashfaq R, Cameron JL, Schulick RD, Yeo CJ, Rahman A, Hinkle DA, Hruban RH, Argani P (2004) Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays. Hum Pathol 35: 357-366 (Pubitemid 38339611)
-
(2004)
Human Pathology
, vol.35
, Issue.3
, pp. 357-366
-
-
Swierczynski, S.L.1
Maitra, A.2
Abraham, S.C.3
Iacobuzio-Donahue, C.A.4
Ashfaq, R.5
Cameron, J.L.6
Schulick, R.D.7
Yeo, C.J.8
Rahman, A.9
Hinkle, D.A.10
Hruban, R.H.11
Argani, P.12
-
26
-
-
32944468551
-
Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma
-
DOI 10.1158/1078-0432.CCR-05-1397
-
Yen MJ, Hsu CY, Mao TL, Wu TC, Roden R, Wang TL, Shih Ie M (2006) Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma. Clin Cancer Res 12: 827-831 (Pubitemid 43259864)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.3
, pp. 827-831
-
-
Yen, M.J.1
Hsu, C.-Y.2
Mao, T.-L.3
Wu, T.-C.4
Roden, R.5
Wang, T.-L.6
Shih, L.-M.7
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