-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2006. CA Cancer J Clin. 2006;56:106-130.
-
(2006)
CA Cancer J Clin.
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
12144288807
-
Pancreatic Cancer Registry in Japan: 20 years of experience
-
Matsuno S, Egawa S, Fukuyama S, et al. Pancreatic Cancer Registry in Japan: 20 years of experience. Pancreas. 2004;28:219-230.
-
(2004)
Pancreas.
, vol.28
, pp. 219-230
-
-
Matsuno, S.1
Egawa, S.2
Fukuyama, S.3
-
3
-
-
0028985078
-
Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study
-
Bramhall SR, Allum WH, Jones AG, et al. Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study. Br J Surg. 1995;82:111-115.
-
(1995)
Br J Surg.
, vol.82
, pp. 111-115
-
-
Bramhall, S.R.1
Allum, W.H.2
Jones, A.G.3
-
4
-
-
0034767957
-
Cancer burden in the year 2000. The global picture
-
Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000. The global picture. Eur J Cancer. 2001;37(suppl 8):S4YS66.
-
(2001)
Eur J Cancer.
, vol.37
, Issue.SUPPL. 8
-
-
Parkin, D.M.1
Bray, F.I.2
Devesa, S.S.3
-
5
-
-
0030069718
-
Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers
-
Chang K, Pastan I. Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc Natl Acad Sci U S A. 1996;93:136-140.
-
(1996)
Proc Natl Acad Sci U S A.
, vol.93
, pp. 136-140
-
-
Chang, K.1
Pastan, I.2
-
6
-
-
0026503664
-
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium
-
Chang K, Pastan I, Willingham MC. Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium. Int J Cancer. 1992;50:373-381.
-
(1992)
Int J Cancer.
, vol.50
, pp. 373-381
-
-
Chang, K.1
Pastan, I.2
Willingham, M.C.3
-
7
-
-
0035674996
-
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: Identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE
-
Argani P, Iacobuzio-Donahue C, Ryu B, et al. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: Identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res. 2001;7:3862-3868.
-
(2001)
Clin Cancer Res.
, vol.7
, pp. 3862-3868
-
-
Argani, P.1
Iacobuzio-Donahue, C.2
Ryu, B.3
-
9
-
-
0037341494
-
Value of mesothelin immunostaining in the diagnosis of mesothelioma
-
Ordonez NG. Value of mesothelin immunostaining in the diagnosis of mesothelioma. Mod Pathol. 2003;16:192-197.
-
(2003)
Mod Pathol.
, vol.16
, pp. 192-197
-
-
Ordonez, N.G.1
-
10
-
-
0142169984
-
Application of mesothelin immunostaining in tumor diagnosis
-
Ordonez NG. Application of mesothelin immunostaining in tumor diagnosis. Am J Surg Pathol. 2003;27:1418-1428.
-
(2003)
Am J Surg Pathol.
, vol.27
, pp. 1418-1428
-
-
Ordonez, N.G.1
-
11
-
-
39749173738
-
Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer
-
Li M, Bharadwaj U, Zhang R, et al. Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer. Mol Cancer Ther. 2008;7:286-296.
-
(2008)
Mol Cancer Ther.
, vol.7
, pp. 286-296
-
-
Li, M.1
Bharadwaj, U.2
Zhang, R.3
-
12
-
-
32944468551
-
Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma
-
Yen MJ, Hsu CY, Mao TL, et al. Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma. Clin Cancer Res. 2006;12:827-831.
-
(2006)
Clin Cancer Res.
, vol.12
, pp. 827-831
-
-
Yen, M.J.1
Hsu, C.Y.2
Mao, T.L.3
-
13
-
-
63949085839
-
High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
-
Cheng WF, Huang CY, Chang MC, et al. High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma. Br J Cancer. 2009;100:1144-1153.
-
(2009)
Br J Cancer.
, vol.100
, pp. 1144-1153
-
-
Cheng, W.F.1
Huang, C.Y.2
Chang, M.C.3
-
14
-
-
28444437055
-
Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis
-
Hassan R, Laszik ZG, Lerner M, et al. Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis. Am J Clin Pathol. 2005;124:838-845.
-
(2005)
Am J Clin Pathol.
, vol.124
, pp. 838-845
-
-
Hassan, R.1
Laszik, Z.G.2
Lerner, M.3
-
15
-
-
12144288836
-
Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays
-
Swierczynski SL, Maitra A, Abraham SC, et al. Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays. Hum Pathol. 2004;35:357-366.
-
(2004)
Hum Pathol.
, vol.35
, pp. 357-366
-
-
Swierczynski, S.L.1
Maitra, A.2
Abraham, S.C.3
-
16
-
-
0019790278
-
Reactivity of a monoclonal antibody with human ovarian carcinoma
-
Bast RC Jr, Feeney M, Lazarus H, et al. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest. 1981;68:1331-1337.
-
(1981)
J Clin Invest.
, vol.68
, pp. 1331-1337
-
-
Bast Jr., R.C.1
Feeney, M.2
Lazarus, H.3
-
17
-
-
0021053493
-
Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125
-
Kabawat SE, Bast RC Jr, Bhan AK, et al. Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125. Int J Gynecol Pathol. 1983;2:275-285.
-
(1983)
Int J Gynecol Pathol.
, vol.2
, pp. 275-285
-
-
Kabawat, S.E.1
Bast Jr., R.C.2
Bhan, A.K.3
-
18
-
-
0031034824
-
Immunohistochemical phenotype of malignant mesothelioma: Predictive value of CA125 and HBME-1 expression
-
Bateman AC, al-Talib RK, Newman T, et al. Immunohistochemical phenotype of malignant mesothelioma: Predictive value of CA125 and HBME-1 expression. Histopathology. 1997;30:49-56.
-
(1997)
Histopathology.
, vol.30
, pp. 49-56
-
-
Bateman, A.C.1
Al-Talib, R.K.2
Newman, T.3
-
19
-
-
0023583596
-
CA 125 in the serum and tissue of patients with gynecological disease
-
Fuith LC, Daxenbichler G, Dapunt O. CA 125 in the serum and tissue of patients with gynecological disease. Arch Gynecol Obstet. 1987;241:157-164.
-
(1987)
Arch Gynecol Obstet.
, vol.241
, pp. 157-164
-
-
Fuith, L.C.1
Daxenbichler, G.2
Dapunt, O.3
-
20
-
-
33847112141
-
Immunohistochemical marker panels for distinguishing between epithelioid mesothelioma and lung adenocarcinoma
-
Kushitani K, Takeshima Y, Amatya VJ, et al. Immunohistochemical marker panels for distinguishing between epithelioid mesothelioma and lung adenocarcinoma. Pathol Int. 2007;57:190-199.
-
(2007)
Pathol Int.
, vol.57
, pp. 190-199
-
-
Kushitani, K.1
Takeshima, Y.2
Amatya, V.J.3
-
21
-
-
33846634622
-
Circulating CA125 in patients with peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion
-
Baratti D, Kusamura S, Martinetti A, et al. Circulating CA125 in patients with peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion. Ann Surg Oncol. 2007;14:500-508.
-
(2007)
Ann Surg Oncol.
, vol.14
, pp. 500-508
-
-
Baratti, D.1
Kusamura, S.2
Martinetti, A.3
-
23
-
-
0029655359
-
Importance of serum CA 125 levels in malignant peritoneal mesothelioma
-
Simsek H, Kadayifci A, Okan E. Importance of serum CA 125 levels in malignant peritoneal mesothelioma. Tumour Biol. 1996;17:1-4.
-
(1996)
Tumour Biol.
, vol.17
, pp. 1-4
-
-
Simsek, H.1
Kadayifci, A.2
Okan, E.3
-
24
-
-
0036560755
-
The CA 125 gene: A newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure
-
O'Brien TJ, Beard JB, Underwood LJ, et al. The CA 125 gene: A newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure. Tumour Biol. 2002;23:154-169.
-
(2002)
Tumour Biol.
, vol.23
, pp. 154-169
-
-
O'Brien, T.J.1
Beard, J.B.2
Underwood, L.J.3
-
25
-
-
0035920171
-
Molecular cloning of the CA125 ovarian cancer antigen: Identification as a new mucin, MUC16
-
Yin BW, Lloyd KO. Molecular cloning of the CA125 ovarian cancer antigen: Identification as a new mucin, MUC16. J Biol Chem. 2001;276:27371-27375.
-
(2001)
J Biol Chem.
, vol.276
, pp. 27371-27375
-
-
Yin, B.W.1
Lloyd, K.O.2
-
26
-
-
33750998782
-
Mesothelin-MUC16 binding is a high affinity N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors
-
Gubbels JA, Belisle J, Onda M, et al. Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol Cancer. 2006;5:50.
-
(2006)
Mol Cancer.
, vol.5
, pp. 50
-
-
Gubbels, J.A.1
Belisle, J.2
Onda, M.3
-
27
-
-
63649151399
-
A binding domain on mesothelin for CA125/MUC16
-
Kaneko O, Gong L, Zhang J, et al. A binding domain on mesothelin for CA125/MUC16. J Biol Chem. 2009;284:3739-3749.
-
(2009)
J Biol Chem.
, vol.284
, pp. 3739-3749
-
-
Kaneko, O.1
Gong, L.2
Zhang, J.3
-
28
-
-
1542365125
-
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion
-
Rump A, Morikawa Y, Tanaka M, et al. Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J Biol Chem. 2004;279:9190-9198.
-
(2004)
J Biol Chem.
, vol.279
, pp. 9190-9198
-
-
Rump, A.1
Morikawa, Y.2
Tanaka, M.3
-
30
-
-
56449108335
-
Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3
-
Bharadwaj U, Li M, Chen C, et al. Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3. Mol Cancer Res. 2008;6:1755-1765.
-
(2008)
Mol Cancer Res.
, vol.6
, pp. 1755-1765
-
-
Bharadwaj, U.1
Li, M.2
Chen, C.3
-
31
-
-
73149108613
-
Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway
-
Chang MC, Chen CA, Hsieh CY, et al. Mesothelin inhibits paclitaxel-induced apoptosis through the PI3K pathway. Biochem J. 2009;424:449-458.
-
(2009)
Biochem J.
, vol.424
, pp. 449-458
-
-
Chang, M.C.1
Chen, C.A.2
Hsieh, C.Y.3
-
32
-
-
77952551039
-
Inhibition of mesothelinYCA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapy
-
Hassan R, Schweizer C, Lu KF, et al. Inhibition of mesothelinYCA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapy. Lung Cancer. 2010;68:455-459.
-
(2010)
Lung Cancer.
, vol.68
, pp. 455-459
-
-
Hassan, R.1
Schweizer, C.2
Lu, K.F.3
-
33
-
-
37449006756
-
Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin
-
Hassan R, Ebel W, Routhier EL, et al. Preclinical evaluation of MORAb-009, a chimeric antibody targeting tumor-associated mesothelin. Cancer Immun. 2007;7:20.
-
(2007)
Cancer Immun.
, vol.7
, pp. 20
-
-
Hassan, R.1
Ebel, W.2
Routhier, E.L.3
-
34
-
-
79952479229
-
A novel high-affinity human monoclonal antibody to mesothelin
-
Ho M, Feng M, Fisher RJ, et al. A novel high-affinity human monoclonal antibody to mesothelin. Int J Cancer. 2011;128:2020-2030.
-
(2011)
Int J Cancer.
, vol.128
, pp. 2020-2030
-
-
Ho, M.1
Feng, M.2
Fisher, R.J.3
-
35
-
-
6044241807
-
The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: Poor prognosis in patients with pancreatic ductal adenocarcinoma
-
Ueda S, Ogata S, Tsuda H, et al. The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: Poor prognosis in patients with pancreatic ductal adenocarcinoma. Pancreas. 2004;29:e1Ye8.
-
(2004)
Pancreas.
, vol.29
-
-
Ueda, S.1
Ogata, S.2
Tsuda, H.3
-
36
-
-
24144457548
-
Assessment of HER-2 status in pancreatic adenocarcinoma: Correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival
-
Saxby AJ, Nielsen A, Scarlett CJ, et al. Assessment of HER-2 status in pancreatic adenocarcinoma: Correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival. Am J Surg Pathol. 2005;29:1125-1134.
-
(2005)
Am J Surg Pathol.
, vol.29
, pp. 1125-1134
-
-
Saxby, A.J.1
Nielsen, A.2
Scarlett, C.J.3
-
37
-
-
32944478346
-
Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer
-
Kindler HL, Friberg G, Singh DA, et al. Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol. 2005;23:8033-8040.
-
(2005)
J Clin Oncol.
, vol.23
, pp. 8033-8040
-
-
Kindler, H.L.1
Friberg, G.2
Singh, D.A.3
-
38
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore MJ, Goldstein D, Hamm J, et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol. 2007;25:1960-1966.
-
(2007)
J Clin Oncol.
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
39
-
-
3042621639
-
Mesothelin: A new target for immunotherapy
-
Hassan R, Bera T, Pastan I. Mesothelin: A new target for immunotherapy. Clin Cancer Res. 2004;10:3937-3942.
-
(2004)
Clin Cancer Res.
, vol.10
, pp. 3937-3942
-
-
Hassan, R.1
Bera, T.2
Pastan, I.3
-
40
-
-
37249025607
-
Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts
-
Hassan R, Broaddus VC,Wilson S, et al. Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts. Clin Cancer Res. 2007;13:7166-7171.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 7166-7171
-
-
Hassan, R.1
Broaddus, V.C.2
Wilson, S.3
-
41
-
-
34548858453
-
Phase i study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
-
Hassan R, Bullock S, Premkumar A, et al. Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers. Clin Cancer Res. 2007;13:5144-5149.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 5144-5149
-
-
Hassan, R.1
Bullock, S.2
Premkumar, A.3
-
42
-
-
37249038187
-
Mesothelin targeted cancer immunotherapy
-
Hassan R, Ho M. Mesothelin targeted cancer immunotherapy. Eur J Cancer. 2008;44:46-53.
-
(2008)
Eur J Cancer.
, vol.44
, pp. 46-53
-
-
Hassan, R.1
Ho, M.2
-
43
-
-
77957263361
-
Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo
-
Inami K, Abe M, Takeda K, et al. Antitumor activity of anti-C-ERC/mesothelin monoclonal antibody in vivo. Cancer Sci. 2010;101:969-974.
-
(2010)
Cancer Sci.
, vol.101
, pp. 969-974
-
-
Inami, K.1
Abe, M.2
Takeda, K.3
|