Repeated oral dose toxicity of iron oxide nanoparticles: Biochemical and histopathological alterations in different tissues of rats

Journal of Nanoscience and Nanotechnology

Volumn 12, Issue 3, 2012, Pages 2149-2159

  Kumari, Monika ^a   Rajak, Sheik ^a   Singh, Shailendra P ^a   Kumari, Srinivas I ^a   Kumar, Putcha U ^b   Murty, Upadhyayula S N ^a   Mahboob, Mohammed ^a   Grover, Paramjit ^a   Rahman, Mohammed F ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

Biochemical Enzymes; Histopathology; Iron Oxide Nanoparticles; Rat; Tissues

Indexed keywords

ACETYLCHOLINESTERASE; ADAPTIVE MECHANISM; ADVERSE EFFECT; ASPARTATES; ATPASES; BIOCHEMICAL PARAMETERS; BLOOD STREAMS; BRAIN TISSUE; BULK MATERIALS; DOSE-DEPENDENT; FOCAL AREA; HIGH DOSE; HISTOPATHOLOGICAL ANALYSIS; HISTOPATHOLOGY; IRON NANOPARTICLES; IRON OXIDE NANOPARTICLE; LACTATE DEHYDROGENASE; LOW DOSE; ORAL DOSE; ROUND CELLS; SYNAPTIC TRANSMISSION; TISSUE NECROSIS; TOXICOLOGICAL EFFECTS; WHITE PULPS; WISTAR RAT;

AMINO ACIDS; ANIMALS; BODY FLUIDS; ENZYMES; HISTOLOGY; IRON OXIDES; METAL NANOPARTICLES; SODIUM; TISSUE; TOXICITY;

RATS;

ADENOSINE TRIPHOSPHATASE; FERRIC ION; FERRIC OXIDE; METAL NANOPARTICLE;

ANIMAL; ARTICLE; DRUG SURVEILLANCE PROGRAM; FEMALE; METABOLISM; ORAL DRUG ADMINISTRATION; RAT; SYNAPTIC TRANSMISSION; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; WISTAR RAT;

ADENOSINE TRIPHOSPHATASES; ADMINISTRATION, ORAL; ANIMALS; FEMALE; FERRIC COMPOUNDS; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RATS, WISTAR; SYNAPTIC TRANSMISSION; TISSUE DISTRIBUTION;

EID: 84863002431     PISSN: 15334880     EISSN: 15334899     Source Type: Journal    
DOI: 10.1166/jnn.2012.5796     Document Type: Article

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