Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment

Toxicological Sciences

Volumn 107, Issue 2, 2009, Pages 342-351

  Zhu, Mo Tao ^a   Feng, Wei Yue ^a,c   Wang, Yun ^a,b   Wang, Bing ^a   Wang, Meng ^a   Ouyang, Hong ^a   Zhao, Yu Liang ^a   Chai, Zhi Fang ^a  

^a INSTITUTE OF HIGH ENERGY PHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c NONE   (China)

Author keywords

Extrapulmonary translocation; Ferric oxide nanoparticle; Health risk assessment; Lung retention; Particokinetics

Indexed keywords

FERRIC OXIDE; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CARDIOTOXICITY; COMPARTMENT MODEL; CONTROLLED STUDY; EXCRETION; HEALTH HAZARD; HISTOLOGY; LUNG CLEARANCE; LUNG TOXICITY; MACROPHAGE; MALE; MASS SPECTROMETRY; METABOLISM; MONOCYTE; NONHUMAN; PHAGOCYTOSIS; RAT; RESPIRATORY DISTRESS; RISK ASSESSMENT; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; TOXICITY TESTING; TOXICOKINETICS;

ADMINISTRATION, INHALATION; ANIMALS; AREA UNDER CURVE; FERRIC COMPOUNDS; HALF-LIFE; HUMANS; INTUBATION, INTRATRACHEAL; IRON RADIOISOTOPES; LUNG; MACROPHAGES; MALE; MASS SPECTROMETRY; MICROSCOPY, ELECTRON, TRANSMISSION; MONOCYTES; NANOPARTICLES; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; U937 CELLS;

RATTUS;

EID: 59249109098     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn245     Document Type: Article

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