Mechanism of inhibition of lipopolysaccharide-induced interferon-β production by 2-aminopurine

Molecular Immunology

Volumn 52, Issue 3-4, 2012, Pages 299-304

  Sugiyama, Tsuyoshi ^a   Gotou, Takaki ^a   Moriyama, Kazuya ^a   Kajiura, Nodoka ^a   Hasegawa, Takuya ^a   Tomida, Junko ^a   Takahashi, Keita ^a   Komatsu, Takayuki ^b   Ueda, Hiroshi ^c   Sato, Katsuya ^c   Tokoro, Shunji ^a   Neri, Paola ^a   Mori, Hiroshi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c GIFU UNIVERSITY   (Japan)

Author keywords

2 Aminopurine; Akt; Double stranded RNA dependent protein kinase; Innate immunity; Interferon regulatory factor 3; Toll like receptor

Indexed keywords

2 AMINOPURINE; BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; MUTANT PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE B; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; INTERFERON PRODUCTION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION;

2-AMINOPURINE; 3T3 CELLS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL LINE; GENES, REPORTER; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84862978964     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.06.008     Document Type: Article

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