메뉴 건너뛰기




Volumn 27, Issue 2, 2012, Pages 585-593

Angelica sinensis suppresses human lung adenocarcinoma A549 cell metastasis by regulating MMPs/TIMPs and TGF-β1

Author keywords

Angelica sinensis; Metastasis; MMP 2; MMP 9; Transforming growth factor

Indexed keywords

GELATINASE A; GELATINASE B; HERBACEOUS AGENT; MATRIX METALLOPROTEINASE; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84862964672     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1527     Document Type: Article
Times cited : (29)

References (56)
  • 2
    • 36048978127 scopus 로고    scopus 로고
    • Effect of angelica sinensis on fibroblast in bleomycin induced pulmonary fibrosis in rats
    • Guo GS and Wang H: Effect of angelica sinensis on fibroblast in bleomycin induced pulmonary fibrosis in rats. Wu Han Da Xue Xue Ba (Yi Xue Ban) 28: 560-563, 2007.
    • (2007) Wu Han Da Xue Xue Ba (Yi Xue Ban) , vol.28 , pp. 560-563
    • Guo, G.S.1    Wang, H.2
  • 5
    • 84862929584 scopus 로고
    • Effect of some drugs of promoting blood circulation and removing blood stasis on the pulmonary metastases of mouse hepatoma cells
    • Li XT, Wang YQ and Fu Nw: Effect of some drugs of promoting blood circulation and removing blood stasis on the pulmonary metastases of mouse hepatoma cells. J Trad Chinese Med 8: 75-77, 1980.
    • (1980) J Trad Chinese Med , vol.8 , pp. 75-77
    • Li, X.T.1    Wang, Y.Q.2    Fu, N.3
  • 6
    • 0029460816 scopus 로고
    • Clinical study on effect of combined treatment of fuchunpian with radiotherapy on nasopharyngeal carcinoma
    • Han JQ, Chen YT, Man YY, et al: Clinical study on effect of combined treatment of fuchunpian with radiotherapy on nasopharyngeal carcinoma. Zhongguo Zhong Xi Yi Jie He Za Zhi 15: 710-712, 1995.
    • (1995) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.15 , pp. 710-712
    • Han, J.Q.1    Chen, Y.T.2    Man, Y.Y.3
  • 7
    • 65749311696 scopus 로고
    • The effect of paeonia rubba 801 on the occurrence of lung metastasis in Walker 256 tumou
    • Yu JG, Hu SK, Li XL, et al: The effect of paeonia rubba 801 on the occurrence of lung metastasis in Walker 256 tumou. Chin J Cancer Res 5: 226-234, 1993.
    • (1993) Chin J Cancer Res , vol.5 , pp. 226-234
    • Yu, J.G.1    Hu, S.K.2    Li, X.L.3
  • 8
    • 0035722954 scopus 로고    scopus 로고
    • Matrix metalloproteinases in lung biology
    • DOI 10.1186/rr33
    • Parks WC and Shapiro SD: Matrix metalloproteinases in lung biology. Respir Res 2: 10-9, 2001. (Pubitemid 34187902)
    • (2001) Respiratory Research , vol.2 , Issue.1 , pp. 10-19
    • Parks, W.C.1    Shapiro, S.D.2
  • 9
    • 0038575443 scopus 로고    scopus 로고
    • Extracellular matrix remodelling: The role of matrix metalloproteinases
    • Stamenkovic I: Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol 200: 448-464, 2003.
    • (2003) J Pathol , vol.200 , pp. 448-464
    • Stamenkovic, I.1
  • 10
    • 0027469921 scopus 로고
    • Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma
    • Brown PD, Bloxidge RE, Stuart NS, Gatter KC and Carmichael J: Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small cell lung carcinoma. J Natl Cancer Inst 85: 574-578, 1993. (Pubitemid 23110933)
    • (1993) Journal of the National Cancer Institute , vol.85 , Issue.7 , pp. 574-578
    • Brown, P.D.1    Bloxidge, R.E.2    Stuart, S.A.3    Gatter, K.C.4    Carmichael, J.5
  • 11
    • 0031935056 scopus 로고    scopus 로고
    • 72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells
    • González-Avila G, Iturria C, Vadillo F, Terán L, Selman M and Pérez-Tamayo R: 72-kD (MMP-2) and 92-kD (MMP-9) type IV collagenase production and activity in different histologic types of lung cancer cells. Pathobiology 66: 5-16, 1998.
    • (1998) Pathobiology , vol.66 , pp. 5-16
    • González-Avila, G.1    Iturria, C.2    Vadillo, F.3    Terán, L.4    Selman, M.5    Pérez-Tamayo, R.6
  • 13
    • 0025193320 scopus 로고
    • Basememt membrane type IV collagen degradation: Evidence for the involvement of a proteolytic cascade independent of metalloproteinases
    • Mackay AR, Corbitt RH, Hartzler JL and Thorgeirsson UP: Basement membrane type IV collagen degradation: evidence for the involvement of a proteolytic cascade independent of metalloproteinases. Cancer Res 50: 5997-6001, 1990. (Pubitemid 20331412)
    • (1990) Cancer Research , vol.50 , Issue.18 , pp. 5997-6001
    • Mackay, A.R.1    Corbitt, R.H.2    Hartzler, J.L.3    Thorgeirsson, U.P.4
  • 14
    • 0030927413 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung
    • Kodate M, Kasai T, Hashimoto H, Yasumoto K, Iwata Y and Manabe H: Expression of matrix metalloproteinase (gelatinase) in T1 adenocarcinoma of the lung. Pathol Int 47: 461-469, 1997. (Pubitemid 27280170)
    • (1997) Pathology International , vol.47 , Issue.7 , pp. 461-469
    • Kodate, M.1    Kasai, T.2    Hashimoto, H.3    Yasumoto, K.4    Iwata, Y.5    Manabe, H.6
  • 15
    • 0028073883 scopus 로고
    • The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis
    • Ray JM and Stetler-Stevenson WG: The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur Respir J 7: 2062-2072, 1994. (Pubitemid 24366302)
    • (1994) European Respiratory Journal , vol.7 , Issue.11 , pp. 2062-2072
    • Ray, J.M.1    Stetler-Stevenson, W.G.2
  • 16
    • 0029019867 scopus 로고
    • The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family
    • Apte SS, Olsen BR and Murphy G: The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem 270: 14313-14318, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 14313-14318
    • Apte, S.S.1    Olsen, B.R.2    Murphy, G.3
  • 17
    • 0026630048 scopus 로고
    • Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin
    • Goldberg GI, Strongin A, Collier IE, Genrich LT and Marmer BL: Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin. J Biol Chem 267: 4583-4591, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 4583-4591
    • Goldberg, G.I.1    Strongin, A.2    Collier, I.E.3    Genrich, L.T.4    Marmer, B.L.5
  • 20
    • 33646576169 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tumor metastasis
    • DOI 10.1007/s10555-006-7886-9, Metalloproteinases and Cancer
    • Deryugina EI and Quigley JP: Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25: 9-34, 2006. (Pubitemid 43723979)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.1 , pp. 9-34
    • Deryugina, E.I.1    Quigley, J.P.2
  • 21
    • 79960838436 scopus 로고    scopus 로고
    • The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system
    • Wiercinska E, Naber HP, Pardali E, van der Pluijm G, van Dam H and Ten Dijke P: The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system. Breast Cancer Res Treat 128: 657-666, 2011.
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 657-666
    • Wiercinska, E.1    Naber, H.P.2    Pardali, E.3    Van Der Pluijm, G.4    Van Dam, H.5    Ten Dijke, P.6
  • 22
    • 33846821916 scopus 로고    scopus 로고
    • High TGFbeta-Smad Activity Confers Poor Prognosis in Glioma Patients and Promotes Cell Proliferation Depending on the Methylation of the PDGF-B Gene
    • DOI 10.1016/j.ccr.2006.11.023, PII S1535610806003813
    • Bruna A, Darken RS, Rojo F, et al: High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell 11: 147-160, 2007. (Pubitemid 46209848)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 147-160
    • Bruna, A.1    Darken, R.S.2    Rojo, F.3    Ocana, A.4    Penuelas, S.5    Arias, A.6    Paris, R.7    Tortosa, A.8    Mora, J.9    Baselga, J.10    Seoane, J.11
  • 23
    • 33646464082 scopus 로고    scopus 로고
    • Angelica sinensis down-regulates hydroxyproline and Tgfb1 and provides protection in mice with radiation-induced pulmonary fibrosis
    • Han G, Zhou YF, Zhang MS, et al: Angelica sinensis down-regulates hydroxyproline and Tgfb1 and provides protection in mice with radiation-induced pulmonary fibrosis. Radiat Res 165: 546-552, 2006.
    • (2006) Radiat Res , vol.165 , pp. 546-552
    • Han, G.1    Zhou, Y.F.2    Zhang, M.S.3
  • 24
    • 39049188824 scopus 로고    scopus 로고
    • Chinese medicine Angelica sinensis suppresses radiation-induced expression of TNF-alpha and TGF-beta1 in mice
    • Xie CH, Zhang MS, Zhou YF, et al: Chinese medicine Angelica sinensis suppresses radiation-induced expression of TNF-alpha and TGF-beta1 in mice. Oncol Rep 15: 1429-1436, 2006.
    • (2006) Oncol Rep , vol.15 , pp. 1429-1436
    • Xie, C.H.1    Zhang, M.S.2    Zhou, Y.F.3
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCt method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 77956789403 scopus 로고    scopus 로고
    • Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia-reperfusion rats
    • Zhang S, He B, Ge J, et al: Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia-reperfusion rats. Int J Biol Macromol 47: 546-550, 2010.
    • (2010) Int J Biol Macromol , vol.47 , pp. 546-550
    • Zhang, S.1    He, B.2    Ge, J.3
  • 28
    • 77957320958 scopus 로고    scopus 로고
    • Protective effects of Angelica sinensis polysaccharide on immunological liver injury induced by con-canavalin A in mice
    • Yu F: Protective effects of Angelica sinensis polysaccharide on immunological liver injury induced by con-canavalin A in mice. Zhong Yao Cai 32: 1580-1583, 2009.
    • (2009) Zhong Yao Cai , vol.32 , pp. 1580-1583
    • Yu, F.1
  • 29
    • 0035967847 scopus 로고    scopus 로고
    • Protective effect of polysaccharides-enriched fraction from Angelica sinensis on hepatic injury
    • DOI 10.1016/S0024-3205(01)01153-5, PII S0024320501011535
    • Ye YN, Liu ES, Li Y, et al: Protective effect of polysaccharides-enriched fraction from Angelica sinensis on hepatic injury. Life Sci 69: 637-646, 2001. (Pubitemid 32673622)
    • (2001) Life Sciences , vol.69 , Issue.6 , pp. 637-646
    • Ye, Y.N.1    Liu, E.S.L.2    Li, Y.3    So, H.L.4    Cho, C.C.M.5    Sheng, H.P.6    Lee, S.S.7    Cho, C.H.8
  • 30
    • 77952953701 scopus 로고    scopus 로고
    • Hematopoietic effect of water-soluble polysaccharides from Angelica sinensis on mice with acute blood loss
    • Liu PJ, Hsieh WT, Huang SH, Liao HF and Chiang BH: Hematopoietic effect of water-soluble polysaccharides from Angelica sinensis on mice with acute blood loss. Exp Hematol 38: 437-445, 2010.
    • (2010) Exp Hematol , vol.38 , pp. 437-445
    • Liu, P.J.1    Hsieh, W.T.2    Huang, S.H.3    Liao, H.F.4    Chiang, B.H.5
  • 31
    • 67650091140 scopus 로고    scopus 로고
    • Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats
    • Zhang L, Du JR, Wang J, Yu DK, Chen YS, He Y and Wang CY: Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats. Yakugaku Zasshi 129: 855-859, 2009.
    • (2009) Yakugaku Zasshi , vol.129 , pp. 855-859
    • Zhang, L.1    Du, J.R.2    Wang, J.3    Yu, D.K.4    Chen, Y.S.5    He, Y.6    Wang, C.Y.7
  • 32
    • 3242682465 scopus 로고    scopus 로고
    • Protective effect of Ligusticum chuanxiong and Angelica sinensis on endothelial cell damage induced by hydrogen peroxide
    • DOI 10.1016/j.lfs.2004.05.005, PII S0024320504004679
    • Hou YZ, Zhao GR, Yang J, Yuan YJ, Zhu GG and Hiltunen R: Protective effect of Ligusticum chuanxiong and Angelica sinensis on endothelial cell damage induced by hydrogen peroxide. Life Sci 75: 1775-1786, 2004. (Pubitemid 38961800)
    • (2004) Life Sciences , vol.75 , Issue.14 , pp. 1775-1786
    • Hou, Y.Z.1    Zhao, G.R.2    Yang, J.3    Yuan, Y.J.4    Zhu, G.G.5    Hiltunen, R.6
  • 33
    • 77952287178 scopus 로고    scopus 로고
    • A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway
    • Cao W, Li XQ, Wang X, et al: A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway. Phytomedicine 17: 598-605, 2010.
    • (2010) Phytomedicine , vol.17 , pp. 598-605
    • Cao, W.1    Li, X.Q.2    Wang, X.3
  • 34
    • 71849119769 scopus 로고    scopus 로고
    • Characterizations and anti-tumor activities of three acidic polysaccharides from Angelica sinensis (Oliv.) Diels
    • Cao W, Li XQ, Wang X, Li T, Chen X, Liu SB and Mei QB: Characterizations and anti-tumor activities of three acidic polysaccharides from Angelica sinensis (Oliv.) Diels. Int J Biol Macromol 46: 115-122, 2010.
    • (2010) Int J Biol Macromol , vol.46 , pp. 115-122
    • Cao, W.1    Li, X.Q.2    Wang, X.3    Li, T.4    Chen, X.5    Liu, S.B.6    Mei, Q.B.7
  • 35
    • 53649108143 scopus 로고    scopus 로고
    • Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells
    • Kan WL, Cho CH, Rudd JA and Lin G: Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J Ethnopharmacol 120: 36-43, 2008.
    • (2008) J Ethnopharmacol , vol.120 , pp. 36-43
    • Kan, W.L.1    Cho, C.H.2    Rudd, J.A.3    Lin, G.4
  • 36
    • 49949118496 scopus 로고    scopus 로고
    • Structural analysis and anti-tumor activity in vivo of polysaccharide APS-2a from Angelica sinensis
    • Cao W, Li XQ, Hou Y, Fan HT, Zhang XN and Mei QB: Structural analysis and anti-tumor activity in vivo of polysaccharide APS-2a from Angelica sinensis. Zhong Yao Cai 31: 261-266, 2008.
    • (2008) Zhong Yao Cai , vol.31 , pp. 261-266
    • Cao, W.1    Li, X.Q.2    Hou, Y.3    Fan, H.T.4    Zhang, X.N.5    Mei, Q.B.6
  • 37
    • 33750482953 scopus 로고    scopus 로고
    • The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo
    • Tsai NM, Chen YL, Lee CC, et al: The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo. J Neurochem 99: 1251-1262, 2006.
    • (2006) J Neurochem , vol.99 , pp. 1251-1262
    • Tsai, N.M.1    Chen, Y.L.2    Lee, C.C.3
  • 38
    • 18244390977 scopus 로고    scopus 로고
    • The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo
    • Tsai NM, Lin SZ, Lee CC, et al: The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. Clin Cancer Res 11: 3475-3484, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 3475-3484
    • Tsai, N.M.1    Lin, S.Z.2    Lee, C.C.3
  • 39
    • 3142655814 scopus 로고    scopus 로고
    • Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis
    • Cheng YL, Chang WL, Lee SC, et al: Acetone extract of Angelica sinensis inhibits proliferation of human cancer cells via inducing cell cycle arrest and apoptosis. Life Sci 75: 1579-1594, 2004.
    • (2004) Life Sci , vol.75 , pp. 1579-1594
    • Cheng, Y.L.1    Chang, W.L.2    Lee, S.C.3
  • 41
    • 27944466104 scopus 로고    scopus 로고
    • Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: Is it appropriate?
    • DOI 10.1097/01.gme.0000184419.65943.01
    • Lau CB, Ho TC, Chan TW and Kim SC: Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 12: 734-740, 2005. (Pubitemid 41669126)
    • (2005) Menopause , vol.12 , Issue.6 , pp. 734-740
    • Lau, C.B.S.1    Ho, T.C.Y.2    Chan, T.W.L.3    Kim, S.C.F.4
  • 42
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • Fidler IJ: The organ microenvironment and cancer metastasis. Differentiation 70: 498-505, 2005.
    • (2005) Differentiation , vol.70 , pp. 498-505
    • Fidler, I.J.1
  • 43
    • 0034567942 scopus 로고    scopus 로고
    • Expression of tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma
    • Joo YE, Seo YH, Lee WS, et al: Expression of tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma. Korean J Intern Med 15: 171-178, 2000.
    • (2000) Korean J Intern Med , vol.15 , pp. 171-178
    • Joo, Y.E.1    Seo, Y.H.2    Lee, W.S.3
  • 44
    • 33846944319 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-2 improves antitumor efficacy of a replicating adenovirus in vivo
    • Kim MH, Bodenstine TM, Sumerel LA, Rivera AA, Baker AH and Douglas JT: Tissue inhibitor of metalloproteinases-2 improves antitumor efficacy of a replicating adenovirus in vivo. Cancer Biol Ther 5: 1647-1653, 2006.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1647-1653
    • Kim, M.H.1    Bodenstine, T.M.2    Sumerel, L.A.3    Rivera, A.A.4    Baker, A.H.5    Douglas, J.T.6
  • 46
    • 16844381072 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase 1 is an independent predictor of prognosis in patients with nonsmall cell lung carcinoma who undergo resection with curative intent
    • DOI 10.1002/cncr.20965
    • Gouyer V, Conti M, Devos P, et al: Tissue inhibitor of metallo-proteinase-1 is an independent predictor of prognosis in patients with non-small cell lung carcinoma who undergo resection with curativeintent. Cancer 103: 1676-1684, 2005. (Pubitemid 40490029)
    • (2005) Cancer , vol.103 , Issue.8 , pp. 1676-1684
    • Gouyer, V.1    Conti, M.2    Devos, P.3    Zerimech, F.4    Copin, M.-C.5    Creme, E.6    Wurtz, A.7    Porte, H.8    Huet, G.9
  • 48
    • 0025988402 scopus 로고
    • Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases
    • Bertaux B, Hornebeck W, Eisen AZ and Dubertret L: Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J Invest Dermatol 97: 679-685, 1991.
    • (1991) J Invest Dermatol , vol.97 , pp. 679-685
    • Bertaux, B.1    Hornebeck, W.2    Eisen, A.Z.3    Dubertret, L.4
  • 49
    • 0026568011 scopus 로고
    • Growth-promoting activity of tissue inhibitor of metalloproteinases- 1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum
    • Hayakawa T, Yamashita K, Tanzawa K, Uchijima E and Iwata K: Growth-promoting activity of tissue inhibitor of metalloproteinases- 1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum. FEBS Lett 298: 29-32, 1992.
    • (1992) FEBS Lett , vol.298 , pp. 29-32
    • Hayakawa, T.1    Yamashita, K.2    Tanzawa, K.3    Uchijima, E.4    Iwata, K.5
  • 51
    • 0033572494 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells
    • Li G, Fridman R and Kim HR: Tissue inhibitor of metalloproteinase- 1 inhibits apoptosis of human breast epithelial cells. Cancer Res 59: 6267-6275, 1999. (Pubitemid 30035652)
    • (1999) Cancer Research , vol.59 , Issue.24 , pp. 6267-6275
    • Li, G.1    Fridman, R.2    Choi, K.H.-R.3
  • 54
    • 0029097977 scopus 로고
    • Decreased degradative enzymes in mesangial cells cultured in high glucose media
    • Leehey DJ, Song RH, Alavi N and Singh AK: Decreased degradative enzymes in mesangial cells cultured in high glucose media. Diabetes 44: 929-935, 1995.
    • (1995) Diabetes , vol.44 , pp. 929-935
    • Leehey, D.J.1    Song, R.H.2    Alavi, N.3    Singh, A.K.4
  • 55
    • 0032849144 scopus 로고    scopus 로고
    • Competitive RT-PCR for measuring metalloproteinase gene expression in humanmesangial cells exposed to a hyperglycemic environment
    • Death AK, Yue DK and Turtle JR: Competitive RT-PCR for measuring metalloproteinase gene expression in humanmesangial cells exposed to a hyperglycemic environment. Biotechniques 27: 512-518, 1999.
    • (1999) Biotechniques , vol.27 , pp. 512-518
    • Death, A.K.1    Yue, D.K.2    Turtle, J.R.3
  • 56
    • 0030442543 scopus 로고    scopus 로고
    • Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture
    • Abdel Wahab N and Mason RM: Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture. Biochem J 320: 777-783, 1996. (Pubitemid 27013791)
    • (1996) Biochemical Journal , vol.320 , Issue.3 , pp. 777-783
    • Abdel, W.N.1    Mason, R.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.