Synthesis and anticancer activity of indolin-2-one derivatives bearing the 4-thiazolidinone moiety

Archiv der Pharmazie

Volumn 345, Issue 1, 2012, Pages 73-80

  Wang, Shuobing ^a   Zhao, Yanfang ^a   Zhu, Wufu ^a   Liu, Ying ^a   Guo, Kaixing ^a   Gong, Ping ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

4 Thiazolidinone; Anticancer activity; Indolin 2 one

Indexed keywords

2 (5 (2 FLUOROBENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 2 (5 (4 FLUOROBENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 2 (5 (4 TRIFLUOROMETHYLBENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 2 (5 BENZYLIDENE 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 4 THIAZOLIDINONE DERIVATIVE; ETHYL 2 (5 (2 FLUOROBENZYLIDENE) 2 (2 OXO 5 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (2 FLUOROBENZYLIDENE) 2 (2 OXO 5 METHYLINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (2 FLUOROBENZYLIDENE) 2 (2 OXO 6 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (2,4 DICHLOROBENZYLIDENE) 2 (2 OXO 5 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (3,4,5 TRIMETHOXYBENZYLIDENE) 2 (2 OXO 5 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL) ACETATE; ETHYL 2 (5 (3,4,5 TRIMETHOXYBENZYLIDENE) 2 (2 OXO 5 METHYLINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (3,4,5 TRIMETHOXYBENZYLIDENE) 2 (2 OXO INDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 FLUOROBENZYLIDENE) 2 (2 OXO 5 BROMOINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 FLUOROBENZYLIDENE) 2 (2 OXO 5 METHYLINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 FLUOROBENZYLIDENE) 2 (2 OXO 6 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 FLUOROBENZYLIDENE) 2 (2 OXO INDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 TRIFLUOROMETHYLBENZYLIDENE) 2 (2 OXO 5 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 (4 TRIFLUOROMETHYLBENZYLIDENE) 2 (2 OXO INDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 BENZYLIDENE 2 (2 OXO 5 METHYLINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 BENZYLIDENE 2 (2 OXO 6 FLUOROINDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; ETHYL 2 (5 BENZYLIDENE 2 (2 OXO INDOLIN 3 YLIDENE) 4 OXOTHIAZOLIDIN 3 YL)ACETATE; INDIRUBIN; INDOLE DERIVATIVE; RHODANINE; SUNITINIB; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMICAL BOND; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PRIORITY JOURNAL; THERMODYNAMICS;

ANTINEOPLASTIC AGENTS; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; HT29 CELLS; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 84862959095     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100082     Document Type: Article

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