메뉴 건너뛰기




Volumn 19, Issue 4, 2010, Pages 389-393

The role of LRP8 (ApoER2) in the pathophysiology of the antiphospholipid syndrome

Author keywords

Antiphospholipid serum; GPIb; LDL receptor

Indexed keywords

BETA2 GLYCOPROTEIN 1; BETA2 GLYCOPROTEIN 1 ANTIBODY; BLOOD CLOTTING FACTOR 6; GLYCOPROTEIN IB ALPHA; LIPOCORTIN 2; LOW DENSITY LIPOPROTEIN RECEPTOR PROTEIN 8; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MEGALIN; P SELECTIN GLYCOPROTEIN LIGAND 1; PHOSPHOLIPID ANTIBODY; PROTEIN C; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 77951213979     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203309360542     Document Type: Review
Times cited : (15)

References (49)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S., Lockshin MD, Atsumi T., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006 ; 4: 295-306.
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 2
    • 0141517177 scopus 로고    scopus 로고
    • Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic disease
    • Arnout J., Vermylen J. Current status and implications of autoimmune antiphospholipid antibodies in relation to thrombotic disease. J Thromb Haemost 2003 ; 1: 931-942.
    • (2003) J Thromb Haemost , vol.1 , pp. 931-942
    • Arnout, J.1    Vermylen, J.2
  • 3
    • 39549099464 scopus 로고    scopus 로고
    • Current insight into diagnostics and pathophysiology of the antiphospholipid syndrome
    • Urbanus RT, Derksen RH, de Groot PG Current insight into diagnostics and pathophysiology of the antiphospholipid syndrome. Blood Rev 2008 ; 22: 93-105.
    • (2008) Blood Rev , vol.22 , pp. 93-105
    • Urbanus, R.T.1    Derksen, R.H.2    De Groot, P.G.3
  • 4
    • 0037370733 scopus 로고    scopus 로고
    • Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: A systematic review of the literature
    • DOI 10.1182/blood-2002-02-0441
    • Galli M., Luciani D., Bertolini G., Barbui T. Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2003 ; 101: 1827-1832. (Pubitemid 36237580)
    • (2003) Blood , vol.101 , Issue.5 , pp. 1827-1832
    • Galli, M.1    Luciani, D.2    Bertolini, G.3    Barbui, T.4
  • 5
    • 0142197160 scopus 로고    scopus 로고
    • A simple method to discriminate between β2-glycoprotein- and prothrombin-dependent lupus anticoagulants
    • Simmelink MJA, Derksen Rhwm, Arnout J., de Groot PG A simple method to discriminate between β2-glycoprotein- and prothrombin-dependent lupus anticoagulants. J Thromb Haemost 2003 ; 1: 740-747.
    • (2003) J Thromb Haemost , vol.1 , pp. 740-747
    • Simmelink, M.J.A.1    Rhwm, D.2    Arnout, J.3    De Groot, P.G.4
  • 6
    • 7044223470 scopus 로고    scopus 로고
    • 2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome
    • DOI 10.1182/blood-2004-03-1107
    • de Laat HB, Derksen Rhwm, Urbanus RT, Roest M., de Groot PG β2-Glycoprotein I dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome. Blood 2004 ; 104: 3598-3602. (Pubitemid 39564433)
    • (2004) Blood , vol.104 , Issue.12 , pp. 3598-3602
    • Bas De Laat, H.1    Derksen, R.H.W.M.2    Urbanus, R.T.3    Roest, M.4    De Groot, P.G.5
  • 8
    • 13544276197 scopus 로고    scopus 로고
    • 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis
    • DOI 10.1182/blood-2004-09-3387
    • De Laat B., Derksen RH, Urbanus RT, de Groot PG IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β2-glycoprotein I cause LAC and their presence correlates strongly with thrombosis. Blood 2005 ; 105: 1540-1545. (Pubitemid 40223671)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1540-1545
    • De Laat, B.1    Derksen, R.H.W.M.2    Urbanus, R.T.3    De Groot, P.G.4
  • 9
    • 33846236309 scopus 로고    scopus 로고
    • 2-glycoprotein I: Mutation studies including residues R39 to R43
    • DOI 10.1002/art.22306
    • Ioannou Y., Pericleous C., Giles I., Latchman DS, Isenberg DA, Rahman A. Binding of antiphospholipid antibodies to discontinuous epitopes on domain I of human beta2-glycoprotein I: mutation studies including residues R39 to R43. Arthritis Rheum 2007 ; 56: 280-290. (Pubitemid 46106202)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 280-290
    • Ioannou, Y.1    Pericleous, C.2    Giles, I.3    Latchman, D.S.4    Isenberg, D.A.5    Rahman, A.6
  • 10
    • 65349188214 scopus 로고    scopus 로고
    • In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain i of beta2-glycoprotein I: Proof of concept
    • Ioannou Y., Romay-Penabad Z., Pericleous C., et al. In vivo inhibition of antiphospholipid antibody-induced pathogenicity utilizing the antigenic target peptide domain I of beta2-glycoprotein I: proof of concept. J Thromb Haemost 2009 ; 7: 833-842.
    • (2009) J Thromb Haemost , vol.7 , pp. 833-842
    • Ioannou, Y.1    Romay-Penabad, Z.2    Pericleous, C.3
  • 14
    • 33344456904 scopus 로고    scopus 로고
    • 2-glycoprotein I only after a conformational change
    • DOI 10.1182/blood-2005-05-1943
    • de Laat B., Derksen Rhwm, van Lummel M., Pennings MT, de Groot PG Pathogenic anti-β2-glycoprotein I antibodies recognize domain I of β2-glycoprotein I only after a conformational change. Blood 2006 ; 107: 1916-1924. (Pubitemid 43289372)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1916-1924
    • De Laat, B.1    Derksen, R.H.W.M.2    Van Lummel, M.3    Pennings, M.T.T.4    De Groot, P.G.5
  • 15
    • 0032587622 scopus 로고    scopus 로고
    • Anti-beta2 glycoprotein I-beta2 glycoprotein immune complexes in patients with antiphospholipid syndrome and other autoimmune diseases
    • Biasiolo A., Rampazzo P., Brocco T., et al. Anti-beta2 glycoprotein I-beta2 glycoprotein immune complexes in patients with antiphospholipid syndrome and other autoimmune diseases. Lupus 1999 ; 8: 121-126.
    • (1999) Lupus , vol.8 , pp. 121-126
    • Biasiolo, A.1    Rampazzo, P.2    Brocco, T.3
  • 16
    • 0021844801 scopus 로고
    • Characterization of plasma lipids and lipoproteins in patients with beta 2-glycoprotein i (apolipoprotein H) deficiency. the fasting plasma lipids, lipoproteins, and apolipoproteins were evaluated in 5 subjects
    • Hoeg JM, Segal P., Gregg RE, et al. Characterization of plasma lipids and lipoproteins in patients with beta 2-glycoprotein I (apolipoprotein H) deficiency. The fasting plasma lipids, lipoproteins, and apolipoproteins were evaluated in 5 subjects. Atherosclerosis 1985 ; 55: 25-34.
    • (1985) Atherosclerosis , vol.55 , pp. 25-34
    • Hoeg, J.M.1    Segal, P.2    Gregg, R.E.3
  • 19
    • 0029826217 scopus 로고    scopus 로고
    • Protein C and other cofactors involved in the binding of antiphospholipid antibodies: Relation to the pathogenesis of thrombosis
    • de Groot PG, Horbach DA, Derksen RH Protein C and other cofactors involved in the binding of antiphospholipid antibodies: relation to the pathogenesis of thrombosis. Lupus 1996 ; 5: 488-493.
    • (1996) Lupus , vol.5 , pp. 488-493
    • De Groot, P.G.1    Horbach, D.A.2    Derksen, R.H.3
  • 21
    • 0141445991 scopus 로고    scopus 로고
    • Dimers of β2-glycoprotein i increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein e receptor 2
    • Lutters BCH, Derksen Rhwm, Tekelenburg WL, Lenting PJ, Arnout J., de Groot PG Dimers of β2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2. J Biol Chem 2003 ; 278: 33831-33838.
    • (2003) J Biol Chem , vol.278 , pp. 33831-33838
    • Lutters, B.C.H.1    Rhwm, D.2    Tekelenburg, W.L.3    Lenting, P.J.4    Arnout, J.5    De Groot, P.G.6
  • 22
    • 49349097758 scopus 로고    scopus 로고
    • Updating on the pathogenic mechanisms 5 of the antiphospholipid antibodies-associated pregnancy loss
    • Meroni PL, Gerosa M., Raschi E., Scurati S., Grossi C., Borghi MO Updating on the pathogenic mechanisms 5 of the antiphospholipid antibodies-associated pregnancy loss. Clin Rev Allergy Immunol 2008 ; 34: 332-337.
    • (2008) Clin Rev Allergy Immunol , vol.34 , pp. 332-337
    • Meroni, P.L.1    Gerosa, M.2    Raschi, E.3    Scurati, S.4    Grossi, C.5    Borghi, M.O.6
  • 23
    • 7044254642 scopus 로고    scopus 로고
    • Mechanisms of autoantibody-induced monocyte tissue factor expression
    • DOI 10.1016/j.thromres.2004.06.012, PII S0049384804003202
    • Wolberg AS, Roubey RA Mechanisms of autoantibody-induced monocyte tissue factor expression. Thromb Res 2004 ; 114: 391-396. (Pubitemid 39422571)
    • (2004) Thrombosis Research , vol.114 , Issue.SPEC. ISS. , pp. 391-396
    • Wolberg, A.S.1    Roubey, R.A.S.2
  • 24
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • DOI 10.1182/blood-2005-03-024463
    • Satta N., Dunoyer-Geindre S., Reber G., et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood 2007 ; 109: 1507-1514. (Pubitemid 46239583)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3    Fish, R.J.4    Boehlen, F.5    Kruithof, E.K.O.6    De Moerloose, P.7
  • 26
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z., Montiel-Manzano MG, Shilagard T., et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood 2009 ; 114: 3074-3083.
    • (2009) Blood , vol.114 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 27
    • 47649130477 scopus 로고    scopus 로고
    • Platelet activation by dimeric beta2-glycoprotein i requires signalling via both glycoprotein Ib alpha and apolipoprotein e receptor 2
    • Urbanus RT, Pennings MT, Derksen RH, de Groot PG Platelet activation by dimeric beta2-glycoprotein I requires signalling via both glycoprotein Ib alpha and apolipoprotein E receptor 2. J Thromb Haemost 2008 ; 6: 1405-1412.
    • (2008) J Thromb Haemost , vol.6 , pp. 1405-1412
    • Urbanus, R.T.1    Pennings, M.T.2    Derksen, R.H.3    De Groot, P.G.4
  • 29
    • 34247557490 scopus 로고    scopus 로고
    • The LDL receptor-related protein (LRP) family: An old family of proteins with new physiological functions
    • DOI 10.1080/07853890701214881, PII 777639280
    • May P., Woldt E., Matz RL, Boucher P. The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions. Ann Med 2007 ; 39: 219-228. (Pubitemid 46676481)
    • (2007) Annals of Medicine , vol.39 , Issue.3 , pp. 219-228
    • May, P.1    Woldt, E.2    Matz, R.L.3    Boucher, P.4
  • 30
    • 33645211958 scopus 로고    scopus 로고
    • Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts
    • Mayer H., Duit S., Hauser C., Schneider WJ, Nimpf J. Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts. Mol Cell Biol 2006 ; 26: 19-27.
    • (2006) Mol Cell Biol , vol.26 , pp. 19-27
    • Mayer, H.1    Duit, S.2    Hauser, C.3    Schneider, W.J.4    Nimpf, J.5
  • 32
    • 0035918334 scopus 로고    scopus 로고
    • Identification of a Novel Exon in Apolipoprotein E Receptor 2 Leading to Alternatively Spliced mRNAs Found in Cells of the Vascular Wall but Not in Neuronal Tissue
    • DOI 10.1074/jbc.M011795200
    • Korschineck I., Ziegler S., Breuss J., et al. Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue. J Biol Chem 2001 ; 276: 13192-13197. (Pubitemid 37385248)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.16 , pp. 13192-13197
    • Korschineck, I.1    Ziegler, S.2    Breuss, J.3    Lang, I.4    Lorenz, M.5    Kaun, C.6    Ambros, P.F.7    Binder, B.R.8
  • 33
    • 58549121206 scopus 로고    scopus 로고
    • Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signalling in U937 cells
    • Yang XV, Banerjee Y., Fern'ndez JA, et al. Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signalling in U937 cells. Proc Natl Acad Sci USA 2009 ; 106: 274-279.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 274-279
    • Yang, X.V.1    Banerjee, Y.2    Fern'ndez, J.A.3
  • 37
    • 58449098695 scopus 로고    scopus 로고
    • Platelets and the antiphospholipid syndrome
    • Urbanus R., Derksen Rhwm, de Groot PG Platelets and the antiphospholipid syndrome. Lupus 2008 ; 17: 888-894.
    • (2008) Lupus , vol.17 , pp. 888-894
    • Urbanus, R.1    Rhwm, D.2    De Groot, P.G.3
  • 38
    • 67650770190 scopus 로고    scopus 로고
    • Cooperation between integrin ±vβ3 and VEGFR2 in angiogenesis
    • Somanath PR, Malinin NL, Byzova TV Cooperation between integrin ±vβ3 and VEGFR2 in angiogenesis. Angiogenesis 2009 ; 12: 177-185.
    • (2009) Angiogenesis , vol.12 , pp. 177-185
    • Somanath, P.R.1    Malinin, N.L.2    Byzova, T.V.3
  • 39
    • 33846443236 scopus 로고    scopus 로고
    • Platelet adhesion to dimeric beta2-glycoprotein-I under conditions of flow is mediated by at least two receptors: Glycoprotein Ibalpha and APOER2
    • Pennings MT, Derksen RH, van Lummel M., et al. Platelet adhesion to dimeric beta2-glycoprotein-I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and APOER2. J Thromb Haemost 2007 ; 5: 369-377.
    • (2007) J Thromb Haemost , vol.5 , pp. 369-377
    • Pennings, M.T.1    Derksen, R.H.2    Van Lummel, M.3
  • 40
    • 43749119174 scopus 로고    scopus 로고
    • Protein C supports platelet binding and activation under flow: Role of glycoprotein Ib and apolipoprotein e receptor 2
    • White TC, Berny MA, Tucker EI, et al. Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2. J Thromb Haemost 2008 ; 6: 995-1002.
    • (2008) J Thromb Haemost , vol.6 , pp. 995-1002
    • White, T.C.1    Berny, M.A.2    Tucker, E.I.3
  • 41
    • 70349569047 scopus 로고    scopus 로고
    • Identification of coagulation factor XI as a ligand for platelet apolipoprotein e receptor 2 (ApoER2)
    • White-Adams TC, Berny MA, Tucker EI, et al. Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2). Art Thromb Vasc Biol 2009 ; 29: 1602-1607.
    • (2009) Art Thromb Vasc Biol , vol.29 , pp. 1602-1607
    • White-Adams, T.C.1    Berny, M.A.2    Tucker, E.I.3
  • 42
    • 35449001281 scopus 로고    scopus 로고
    • Activated protein C resistance determined with a thrombin generation-based test is associated with thrombotic events in patients with lupus anticoagulants
    • Liest'l S., Sandset PM, Mowinckel MC, Wisl'ff F. Activated protein C resistance determined with a thrombin generation-based test is associated with thrombotic events in patients with lupus anticoagulants. J Thromb Haemost 2007 ; 5: 2204-2210.
    • (2007) J Thromb Haemost , vol.5 , pp. 2204-2210
    • Liest'l, S.1    Sandset, P.M.2    Mowinckel, M.C.3    Wisl'ff, F.4
  • 43
    • 55249086326 scopus 로고    scopus 로고
    • Activated protein C in sepsis: The promise of nonanticoagulant activated protein C
    • Weiler H., Ruf W. Activated protein C in sepsis: the promise of nonanticoagulant activated protein C. Curr Opin Hematol 2008 ; 15: 487-493.
    • (2008) Curr Opin Hematol , vol.15 , pp. 487-493
    • Weiler, H.1    Ruf, W.2
  • 44
    • 34548222514 scopus 로고    scopus 로고
    • Crystal structure of the TLR4- MD-2 complex with bound endotoxin antagonist eritoran
    • Kim HM, Park BS, Kim JI, et al. Crystal structure of the TLR4- MD-2 complex with bound endotoxin antagonist eritoran. Cell 2007 ; 130: 906-917.
    • (2007) Cell , vol.130 , pp. 906-917
    • Kim, H.M.1    Park, B.S.2    Kim, J.I.3
  • 46
    • 0035507820 scopus 로고    scopus 로고
    • Certain autoantibodies to phosphatidylethanolamine (aPE) recognize factor XI and prekallikrein independently or in addition to the kininogens
    • DOI 10.1006/jaut.2001.0543
    • Sugi T., McIntyre JA Certain autoantibodies to phosphatidylethanolamine (aPE) recognize factor XI and prekallikrein independently or in addition to the kininogens. J Autoimmun 2001 ; 17: 207-214. (Pubitemid 33108756)
    • (2001) Journal of Autoimmunity , vol.17 , Issue.3 , pp. 207-214
    • Sugi, T.1    McIntyre, J.A.2
  • 48
    • 77951235378 scopus 로고    scopus 로고
    • Reply on prolonged bleeding time and lupus anticoagulant: A second paradox in the antiphospholipid syndrome
    • Urbanus RT, de Groot PG, Derksen RH Reply on prolonged bleeding time and lupus anticoagulant: a second paradox in the antiphospholipid syndrome. Arthritis Rheum 2005 ; 52: 1949-1950.
    • (2005) Arthritis Rheum , vol.52 , pp. 1949-1950
    • Urbanus, R.T.1    De Groot, P.G.2    Derksen, R.H.3
  • 49
    • 44849103395 scopus 로고    scopus 로고
    • Pathogenic role of antiphospholipid antibodies
    • DOI 10.1177/0961203308090025, Proceedings of the 7th european Lupus Meeting
    • Salmon J., de Groot PG Pathogenic role of antiphospholipid antibodies. Lupus 2008 ; 17: 405-411. (Pubitemid 351798717)
    • (2008) Lupus , vol.17 , Issue.SPEC. ISS. , pp. 405-411
    • Salmon, J.E.1    De Groot, Ph.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.