Mechanistic insights into LDL nanoparticle-mediated siRNA delivery

Bioconjugate Chemistry

Volumn 23, Issue 1, 2012, Pages 33-41

  Jin, Honglin ^a,b,c   Lovell, Jonathan F ^b,d   Chen, Juan ^b   Lin, Qiaoya ^a,b,c   Ding, Lili ^b   Ng, Kenneth K ^b,d   Pandey, Rajendra K ^e   Manoharan, Muthiah ^e   Zhang, Zhihong ^a   Zheng, Gang ^b,c,d  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e ALNYLAM PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; GENETIC ENGINEERING; MOLECULAR BIOLOGY; RNA;

CHARGED MOLECULE; DELIVERY VEHICLE; GENE DELIVERY; GENE KNOCK DOWN; GENE SILENCING; LOW DENSITY LIPOPROTEIN RECEPTORS; LOW DENSITY LIPOPROTEINS; MECHANISTICS; NANOPARTICLE MORPHOLOGY; SMALL INTERFERING RNA;

NANOPARTICLES;

CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; NANOPARTICLE; SMALL INTERFERING RNA;

ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; GENE DELIVERY SYSTEM; GENE SILENCING; HUMAN; HUMAN CELL; NANOPHARMACEUTICS; PHOTOCHEMISTRY;

EID: 84862908219     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200233n     Document Type: Article

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