Intracellular delivery of siRNA by cell-penetrating peptides modified with cationic oligopeptides

Drug Delivery

Volumn 16, Issue 3, 2009, Pages 153-159

  Ishihara, Tsutomu ^a   Goto, Maoko ^b   Kodera, Kanae ^b   Kanazawa, Hideko ^b   Murakami, Yasuko ^c   Mizushima, Yutaka ^a   Higaki, Megumu ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c MUSASHINO UNIVERSITY   (Japan)

Author keywords

Cationic peptide; Cell penetrating peptide; Endocytosis; Intracellular delivery; SiRNA

Indexed keywords

CATION; CELL PENETRATING PEPTIDE; OLIGOPEPTIDE; PENETRATIN PLUS CATIONIC OLIGOLYSINE PEPTIDE CONJUGATE; SMALL INTERFERING RNA; TRANSACTIVATOR PROTEIN PLUS CATIONIC OLIGOLYSINE PEPTIDE CONJUGATE; TRANSPORTAN PLUS CATIONIC OLIGOLYSINE PEPTIDE CONJUGATE; UNCLASSIFIED DRUG; CARRIER PROTEIN; GALANIN; HYBRID PROTEIN; LUCIFERASE; PENETRATIN; PEPTIDE; TRANSPORTAN; WASP VENOM;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; DRUG CONJUGATION; GENE SILENCING; GENE TARGETING; INTERNALIZATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CHEMISTRY; DRUG ANTAGONISM; DRUG DELIVERY SYSTEM; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENETICS; HELA CELL; HUMAN; PROTEIN TRANSPORT; SYNTHESIS; TUMOR CELL CULTURE;

CARRIER PROTEINS; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; GALANIN; GENE SILENCING; HELA CELLS; HUMANS; LUCIFERASES; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; PEPTIDES; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; WASP VENOMS;

EID: 70349338663     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540902722774     Document Type: Article

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