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Volumn 7, Issue 7, 2012, Pages 1210-1216

Discovery, Synthesis, and invitro Evaluation of West Nile Virus Protease Inhibitors Based on the 9,10-Dihydro-3H,4aH-1,3,9,10a-tetraazaphenanthren-4-one Scaffold

(3) Samanta, Sanjay a Cui, Taian b Lam, Yulin a

a NATIONAL UNIVERSITY OF SINGAPORE (Singapore)

b SCHOOL OF APPLIED SCIENCE (Singapore)

Author keywords

Antiviral agents; Bioorganic chemistry; Docking studies; Inhibitors; Proteases

Indexed keywords

9,10 DIHYDRO 3H,4A H 1,3,9,10A TETRAAZAPHENANTHREN 4 ONE; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 2B; NONSTRUCTURAL PROTEIN 3; PHENANTHRENE DERIVATIVE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; FUSED HETEROCYCLIC RINGS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHIRALITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; WEST NILE FLAVIVIRUS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECT; ENZYMOLOGY; MICROBIAL SENSITIVITY TEST; STEREOISOMERISM; SYNTHESIS;

ANTIVIRAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; HETEROCYCLIC COMPOUNDS, 3-RING; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; WEST NILE VIRUS;

EID: 84862904219 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201200136 Document Type: Article

Times cited : (12)

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