Design, synthesis, and in vitro evaluation of potential west nile virus protease inhibitors based on the 1-oxo-1,2,3,4-tetrahydroisoquinoline and 1-oxo-1,2-dihydroisoquinoline scaffolds

Journal of Combinatorial Chemistry

Volumn 12, Issue 6, 2010, Pages 836-843

  Dou, Dengfeng ^a   Viwanathan, Prasanth ^b   Li, Yi ^d   He, Guijia ^a   Alliston, Kevin R ^a   Lushington, Gerald H ^c   Brown Clay, Joshua D ^b   Padmanabhan, R ^b   Groutas, William C ^a  

^a WICHITA STATE UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,4-TETRAHYDROISOQUINOLINE; ANTIVIRUS AGENT; PROTEINASE INHIBITOR; TETRAHYDROISOQUINOLINE; TETRAHYDROISOQUINOLINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; ENZYMOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS; WEST NILE FLAVIVIRUS;

ANTIVIRAL AGENTS; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; TETRAHYDROISOQUINOLINES; WEST NILE VIRUS;

EID: 78149307658     PISSN: 15204766     EISSN: 15204774     Source Type: Journal    
DOI: 10.1021/cc100091h     Document Type: Article

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