Toxicity studies with 5-hydroxymethylfurfural and its metabolite 5-sulphooxymethylfurfural in wild-type mice and transgenic mice expressing human sulphotransferases 1A1 and 1A2

Archives of Toxicology

Volumn 86, Issue 5, 2012, Pages 701-711

  Bauer Marinovic, Morana ^a   Taugner, Felicitas ^a,b   Florian, Simone ^a   Glatt, Hansruedi ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b Veterinär und Lebensmittelüberwachungsamt ^*  (Germany)

Author keywords

5 Sulphooxymethylfurfural; 5 Hydroxymethylfurfural; Hepatotoxicity; Human sulphotransferases 1A1 and 1A2; Nephrotoxicity

Indexed keywords

5 HYDROXYMETHYLFURFURAL; 5 SULPHOOXYMETHYLFURFURAL; DRINKING WATER; FURAN DERIVATIVE; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1; SULFOTRANSFERASE 1A2; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE CLUSTER; HYPERPLASIA; INFLAMMATION; KIDNEY TUBULE NECROSIS; LIVER CELL; LIVER TOXICITY; MALE; MORTALITY; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SULFATION; TISSUE REGENERATION; TRANSGENIC MOUSE;

ANIMALS; ARYLSULFOTRANSFERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING WATER; FURALDEHYDE; HEPATOCYTES; INJECTIONS, INTRAPERITONEAL; KIDNEY TUBULES, PROXIMAL; LIVER; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; NECROSIS;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 84862903595     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0807-5     Document Type: Article

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