메뉴 건너뛰기




Volumn 17, Issue 3, 2012, Pages 190-195

Molecular and genetic bases of neuroblastoma

Author keywords

Molecular and genetic abnormality; Neuroblastoma

Indexed keywords

ANTINEOPLASTIC AGENT; CD133 ANTIGEN; DECA 14; GENOMIC DNA; POLO LIKE KINASE 1; POLO LIKE KINASE 1 INHIBITOR; PROTEIN KINASE INHIBITOR; RAPAMYCIN; UNCLASSIFIED DRUG;

EID: 84862902806     PISSN: 13419625     EISSN: 14377772     Source Type: Journal    
DOI: 10.1007/s10147-012-0415-7     Document Type: Review
Times cited : (44)

References (58)
  • 1
    • 0037190798 scopus 로고    scopus 로고
    • Genetic parameters of neu-roblastomas
    • Westermann F, Schwab M (2002) Genetic parameters of neu-roblastomas. Cancer Lett 184:127-147
    • (2002) Cancer Lett , vol.184 , pp. 127-147
    • Westermann, F.1    Schwab, M.2
  • 3
    • 0347419432 scopus 로고    scopus 로고
    • Pediatric neuroblastomas: Genetic and epigenetic 'danse macabre'
    • van Noesela MM, Versteeg R (2004) Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'. Gene 325:1-15
    • (2004) Gene , vol.325 , pp. 1-15
    • Van Noesela, M.M.1    Versteeg, R.2
  • 4
    • 0015236227 scopus 로고
    • Special pattern of widespread neuroblastoma with a favourable prognosis
    • D'Angio GJ, Evans AE, Koop CE (1971) Special pattern of widespread neuroblastoma with a favourable prognosis. Lancet 297:1046-1049
    • (1971) Lancet , vol.297 , pp. 1046-1049
    • D'Angio, G.J.1    Evans, A.E.2    Koop, C.E.3
  • 5
    • 0026516472 scopus 로고
    • Max: Functional domains and interaction with c-Myc
    • Kato GJ, Lee WM, Chen LL et al (1992) Max: functional domains and interaction with c-Myc. Genes Dev 6:81-92
    • (1992) Genes Dev , vol.6 , pp. 81-92
    • Kato, G.J.1    Lee, W.M.2    Chen, L.L.3
  • 6
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
    • Zindy F, Eischen CM, Randle DH et al (1998) Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev 12:2424-2433
    • (1998) Genes Dev , vol.12 , pp. 2424-2433
    • Zindy, F.1    Eischen, C.M.2    Randle, D.H.3
  • 7
    • 0021047844 scopus 로고
    • Transposition and amplification of oncogene related sequence in human neurobl-astomas
    • Kohl NE, Kanda N, Schreck RR et al (1983) Transposition and amplification of oncogene related sequence in human neurobl-astomas. Cell 35:359-367
    • (1983) Cell , vol.35 , pp. 359-367
    • Kohl, N.E.1    Kanda, N.2    Schreck, R.R.3
  • 8
    • 0021063273 scopus 로고
    • Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumor
    • Schwab M, Alitalo K, Klempnauer KH et al (1983) Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumor. Nature 305:245-248
    • (1983) Nature , vol.305 , pp. 245-248
    • Schwab, M.1    Alitalo, K.2    Klempnauer, K.H.3
  • 9
    • 0028305310 scopus 로고
    • MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells
    • Corvi R, Amler LC, Savelyeva L et al (1994) MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells. Proc Natl Acad Sci USA 91:5523-5527
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5523-5527
    • Corvi, R.1    Amler, L.C.2    Savelyeva, L.3
  • 10
    • 0032104542 scopus 로고    scopus 로고
    • Amplification of oncogenes in human cancer cells
    • Schwab M (1998) Amplification of oncogenes in human cancer cells. Bioessays 20:473-479
    • (1998) Bioessays , vol.20 , pp. 473-479
    • Schwab, M.1
  • 11
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H et al (1985) Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 313:1111-1116
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 12
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur G, Seeger RC, Schwab M et al (1984) Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224:1121-1124
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.1    Seeger, R.C.2    Schwab, M.3
  • 13
    • 0031049728 scopus 로고    scopus 로고
    • Localized neuro-blastoma: MYCN amplification is the main prognostic factor-results of the NBL 90 study
    • Rubie H, Hartmann O, Michon J et al (1997) Localized neuro-blastoma: MYCN amplification is the main prognostic factor-results of the NBL 90 study. J Clin Oncol 15:1171-1182
    • (1997) J Clin Oncol , vol.15 , pp. 1171-1182
    • Rubie, H.1    Hartmann, O.2    Michon, J.3
  • 14
    • 0028944776 scopus 로고
    • Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma
    • Caron H (1995) Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma. Med Pediatr Oncol 24:215-221
    • (1995) Med Pediatr Oncol , vol.24 , pp. 215-221
    • Caron, H.1
  • 15
    • 0033600283 scopus 로고    scopus 로고
    • Gain of chromosome arm 17q and adverse outcome in patients with neuro-blastoma
    • Bown N, Cotterill S, Lastowska M et al (1999) Gain of chromosome arm 17q and adverse outcome in patients with neuro-blastoma. N Engl J Med 340:1954-1961
    • (1999) N Engl J Med , vol.340 , pp. 1954-1961
    • Bown, N.1    Cotterill, S.2    Lastowska, M.3
  • 16
    • 28444485310 scopus 로고    scopus 로고
    • Clinical significance of serum NM23-H1 protein in neuroblastoma
    • Okabe-Kado J, Kasukabe T, Honma Y et al (2005) Clinical significance of serum NM23-H1 protein in neuroblastoma. Cancer Sci 96:653-660
    • (2005) Cancer Sci , vol.96 , pp. 653-660
    • Okabe-Kado, J.1    Kasukabe, T.2    Honma, Y.3
  • 17
    • 0032554527 scopus 로고    scopus 로고
    • Anti-apoptosis gene, survivin, and prognosis of neuroblastoma
    • Adida C, Berrebi D, Peuchmaur M et al (1998) Anti-apoptosis gene, survivin, and prognosis of neuroblastoma. Lancet 351:882-883
    • (1998) Lancet , vol.351 , pp. 882-883
    • Adida, C.1    Berrebi, D.2    Peuchmaur, M.3
  • 18
    • 0029049717 scopus 로고
    • A region of consistent deletion in neuroblastoma maps within 1p36.2-3
    • White PS, Maris JM, Beltinger C et al (1995) A region of consistent deletion in neuroblastoma maps within 1p36.2-3. Proc Natl Acad Sci USA 92:5520-5524
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5520-5524
    • White, P.S.1    Maris, J.M.2    Beltinger, C.3
  • 19
    • 0035158966 scopus 로고    scopus 로고
    • Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted
    • Caron H, Spieker N, Godfried M et al (2001) Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted. Genes Chromosom Cancer 30:168-174
    • (2001) Genes Chromosom Cancer , vol.30 , pp. 168-174
    • Caron, H.1    Spieker, N.2    Godfried, M.3
  • 20
    • 0035022148 scopus 로고    scopus 로고
    • Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contig
    • Bauer A, Savelyeva L, Claas A et al (2001) Smallest region of overlapping deletion in 1p36 in human neuroblastoma: a 1 Mbp cosmid and PAC contig. Genes Chromosom Cancer 31:228-239
    • (2001) Genes Chromosom Cancer , vol.31 , pp. 228-239
    • Bauer, A.1    Savelyeva, L.2    Claas, A.3
  • 21
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM (2003) Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3:203-216
    • (2003) Nat Rev Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 22
    • 51349157982 scopus 로고    scopus 로고
    • The MYCN oncogene is a direct target of miR-34a
    • Wei JS, Song YK, Durinck S et al (2008) The MYCN oncogene is a direct target of miR-34a. Oncogene 27:5204-5213
    • (2008) Oncogene , vol.27 , pp. 5204-5213
    • Wei, J.S.1    Song, Y.K.2    Durinck, S.3
  • 23
    • 49749150980 scopus 로고    scopus 로고
    • A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene
    • Cole KA, Attiyeh EF, Mosse YP et al (2008) A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene. Mol Cancer Res 6:735-742
    • (2008) Mol Cancer Res , vol.6 , pp. 735-742
    • Cole, K.A.1    Attiyeh, E.F.2    Mosse, Y.P.3
  • 24
    • 33846703338 scopus 로고    scopus 로고
    • CHD5 is a tumor suppressor at human 1p36
    • Bagchi A, Papazoglu C, Wu Y et al (2007) CHD5 is a tumor suppressor at human 1p36. Cell 128:459-475
    • (2007) Cell , vol.128 , pp. 459-475
    • Bagchi, A.1    Papazoglu, C.2    Wu, Y.3
  • 25
    • 54049148638 scopus 로고    scopus 로고
    • KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death
    • Munirajan AK, Ando K, Mukai A et al (2008) KIF1Bbeta functions as a haploinsufficient tumor suppressor gene mapped to chromosome 1p36.2 by inducing apoptotic cell death. J Biol Chem 283:24426-24434
    • (2008) J Biol Chem , vol.283 , pp. 24426-24434
    • Munirajan, A.K.1    Ando, K.2    Mukai, A.3
  • 26
    • 0033517349 scopus 로고    scopus 로고
    • Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas
    • Guo C, White PS, Weiss MJ et al (1999) Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas. Oncogene 18:4948-4957
    • (1999) Oncogene , vol.18 , pp. 4948-4957
    • Guo, C.1    White, P.S.2    Weiss, M.J.3
  • 27
    • 0037239718 scopus 로고    scopus 로고
    • Deletions in chromosome arms 3p and 11q are new prognostic markers in localized and 4s neuroblastoma
    • Spitz R, Hero B, Ernestus K et al (2003) Deletions in chromosome arms 3p and 11q are new prognostic markers in localized and 4s neuroblastoma. Clin Cancer Res 9:52-58
    • (2003) Clin Cancer Res , vol.9 , pp. 52-58
    • Spitz, R.1    Hero, B.2    Ernestus, K.3
  • 28
    • 28144453057 scopus 로고    scopus 로고
    • Chromosome 1p and 11q deletions and outcome in neuroblastoma
    • Attiyeh EF, London WB, Mosse YP et al (2005) Chromosome 1p and 11q deletions and outcome in neuroblastoma. N Engl J Med 353:2243-2253
    • (2005) N Engl J Med , vol.353 , pp. 2243-2253
    • Attiyeh, E.F.1    London, W.B.2    Mosse, Y.P.3
  • 29
    • 58249093955 scopus 로고    scopus 로고
    • The International Neuroblastoma Risk Group (INRG) classification system: An INRG Task Force report
    • Cohn SL, Pearson AD, London WB et al (2009) The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 27:289-297
    • (2009) J Clin Oncol , vol.27 , pp. 289-297
    • Cohn, S.L.1    Pearson, A.D.2    London, W.B.3
  • 30
    • 38349064796 scopus 로고    scopus 로고
    • Novel risk stratification of patients with neuroblastoma by genomic signature which is independent of molecular signature
    • Tomioka N, Oba S, Ohira M et al (2008) Novel risk stratification of patients with neuroblastoma by genomic signature which is independent of molecular signature. Oncogene 27:441-449
    • (2008) Oncogene , vol.27 , pp. 441-449
    • Tomioka, N.1    Oba, S.2    Ohira, M.3
  • 31
    • 51649085884 scopus 로고    scopus 로고
    • Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation
    • Ando K, Ohira M, Ozaki T et al (2008) Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation. Int J Cancer 123:2087-2094
    • (2008) Int J Cancer , vol.123 , pp. 2087-2094
    • Ando, K.1    Ohira, M.2    Ozaki, T.3
  • 32
    • 77952240403 scopus 로고    scopus 로고
    • Bmi1 is a MYCN target gene and regulates tumorigenesis via repression of KIF1Bb and TSLC1 in neuroblastoma
    • Ochiai H, Takenobu H, Nakagawa A et al (2010) Bmi1 is a MYCN target gene and regulates tumorigenesis via repression of KIF1Bb and TSLC1 in neuroblastoma. Oncogene 29:2681-2690
    • (2010) Oncogene , vol.29 , pp. 2681-2690
    • Ochiai, H.1    Takenobu, H.2    Nakagawa, A.3
  • 33
    • 0027285262 scopus 로고
    • Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis
    • Kogner P, Barbany G, Dominici C et al (1993) Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis. Cancer Res 53:2044-2050
    • (1993) Cancer Res , vol.53 , pp. 2044-2050
    • Kogner, P.1    Barbany, G.2    Dominici, C.3
  • 34
    • 0027531016 scopus 로고
    • Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma
    • Nakagawara A, Arima-Nakagawara M, Scavarda NJ et al (1993) Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N Engl J Med 328:847-854
    • (1993) N Engl J Med , vol.328 , pp. 847-854
    • Nakagawara, A.1    Arima-Nakagawara, M.2    Scavarda, N.J.3
  • 35
    • 0028107269 scopus 로고
    • Expression and function of TRK-B and BDNF in human neuroblastomas
    • Nakagawara A, Azar CG, Scavarda NJ et al (1994) Expression and function of TRK-B and BDNF in human neuroblastomas. Mol Cell Biol 14:759-767
    • (1994) Mol Cell Biol , vol.14 , pp. 759-767
    • Nakagawara, A.1    Azar, C.G.2    Scavarda, N.J.3
  • 36
    • 0035866396 scopus 로고    scopus 로고
    • Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
    • Eggert A, Grotzer MA, Zuzak TJ et al (2001) Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res 61:1314-1319
    • (2001) Cancer Res , vol.61 , pp. 1314-1319
    • Eggert, A.1    Grotzer, M.A.2    Zuzak, T.J.3
  • 37
    • 0034066405 scopus 로고    scopus 로고
    • Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
    • Teitz T, Wei T, Valentine MB et al (2000) Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 6:529-535
    • (2000) Nat Med , vol.6 , pp. 529-535
    • Teitz, T.1    Wei, T.2    Valentine, M.B.3
  • 38
    • 0031749533 scopus 로고    scopus 로고
    • Loss of heterozygosity of 3p markers in neuroblastoma tumours implicate a tumour-suppressor locus distal to the FHIT gene
    • Ejeskar K, Aburatani H, Abrahamsson J et al (1998) Loss of heterozygosity of 3p markers in neuroblastoma tumours implicate a tumour-suppressor locus distal to the FHIT gene. Br J Cancer 77:1787-1791
    • (1998) Br J Cancer , vol.77 , pp. 1787-1791
    • Ejeskar, K.1    Aburatani, H.2    Abrahamsson, J.3
  • 39
    • 0035829657 scopus 로고    scopus 로고
    • RASSF1A promoter region CpG island hypermethylation in phaeochromo-cytomas and neuroblastoma tumours
    • Astuti D, Agathanggelou A, Honorio S et al (2001) RASSF1A promoter region CpG island hypermethylation in phaeochromo-cytomas and neuroblastoma tumours. Oncogene 20:7573-7577
    • (2001) Oncogene , vol.20 , pp. 7573-7577
    • Astuti, D.1    Agathanggelou, A.2    Honorio, S.3
  • 40
    • 4544265599 scopus 로고    scopus 로고
    • Germline PHOX2B mutation in hereditary neuroblastoma
    • Mosse YP, Laudenslager M, Khazi D et al (2004) Germline PHOX2B mutation in hereditary neuroblastoma. Am J Hum Genet 75:727-730
    • (2004) Am J Hum Genet , vol.75 , pp. 727-730
    • Mosse, Y.P.1    Laudenslager, M.2    Khazi, D.3
  • 41
    • 12144291333 scopus 로고    scopus 로고
    • Germ-line mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma
    • Trochet D, Bourdeaut F, Janoueix-Lerosey I et al (2004) Germ-line mutations of the paired-like homeobox 2B (PHOX2B) gene in neuroblastoma. Am J Hum Genet 74:761-764
    • (2004) Am J Hum Genet , vol.74 , pp. 761-764
    • Trochet, D.1    Bourdeaut, F.2    Janoueix-Lerosey, I.3
  • 42
    • 54049094708 scopus 로고    scopus 로고
    • Identification of ALK as a major familial neuroblastoma predisposition gene
    • Mossé YP, Laudenslager M, Longo L et al (2008) Identification of ALK as a major familial neuroblastoma predisposition gene. Nature 455:930-935
    • (2008) Nature , vol.455 , pp. 930-935
    • Mossé, Y.P.1    Laudenslager, M.2    Longo, L.3
  • 43
    • 54049149961 scopus 로고    scopus 로고
    • Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
    • Janoueix-Lerosey I, Lequin D, Brugières L et al (2008) Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature 455:967-970
    • (2008) Nature , vol.455 , pp. 967-970
    • Janoueix-Lerosey, I.1    Lequin, D.2    Brugières, L.3
  • 44
    • 54049120220 scopus 로고    scopus 로고
    • Activating mutations in ALK provide a therapeutic target in neuroblastoma
    • George RE, Sanda T, Hanna M et al (2008) Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 455:975-978
    • (2008) Nature , vol.455 , pp. 975-978
    • George, R.E.1    Sanda, T.2    Hanna, M.3
  • 45
    • 54049118823 scopus 로고    scopus 로고
    • Oncogenic mutations of ALK kinase in neuroblastoma
    • Chen Y, Takita J, Choi YL et al (2008) Oncogenic mutations of ALK kinase in neuroblastoma. Nature 455:971-974
    • (2008) Nature , vol.455 , pp. 971-974
    • Chen, Y.1    Takita, J.2    Choi, Y.L.3
  • 46
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A Pediatric Oncology Group study
    • Look AT, Hayes FA, Shuster JJ et al (1991) Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 9:581-591
    • (1991) J Clin Oncol , vol.9 , pp. 581-591
    • Look, A.T.1    Hayes, F.A.2    Shuster, J.J.3
  • 47
    • 4544230424 scopus 로고    scopus 로고
    • Characteristics of stem cells from human neuroblastoma cell lines and in tumors
    • Walton JD, Kattan DR, Thomas SK et al (2004) Characteristics of stem cells from human neuroblastoma cell lines and in tumors. Neoplasia 6:645-838
    • (2004) Neoplasia , vol.6 , pp. 645-838
    • Walton, J.D.1    Kattan, D.R.2    Thomas, S.K.3
  • 48
    • 37049033079 scopus 로고    scopus 로고
    • Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell
    • Hansford LM, McKee AE, Zhang L et al (2007) Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell. Cancer Res 67:11234-11243
    • (2007) Cancer Res , vol.67 , pp. 11234-11243
    • Hansford, L.M.1    McKee, A.E.2    Zhang, L.3
  • 49
    • 77956954455 scopus 로고    scopus 로고
    • Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stemcell-basedsmallmoleculescreens
    • Smith KM, Datti A, Fujitani M et al (2010) Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stemcell-basedsmallmoleculescreens.EMBOMolMed2:371-384
    • (2010) EMBOMolMed , vol.2 , pp. 371-384
    • Smith, K.M.1    Datti, A.2    Fujitani, M.3
  • 50
    • 79951833085 scopus 로고    scopus 로고
    • Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells
    • Grinshtein N, Datti A, Fujitani M et al (2011) Small molecule kinase inhibitor screen identifies polo-like kinase 1 as a target for neuroblastoma tumor-initiating cells. Cancer Res 71:1385-1395
    • (2011) Cancer Res , vol.71 , pp. 1385-1395
    • Grinshtein, N.1    Datti, A.2    Fujitani, M.3
  • 51
    • 0034811912 scopus 로고    scopus 로고
    • Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glyco-protein
    • Corbeil D, Fargeas CA, Huttner WB (2001) Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glyco-protein. Biochem Biophys Res Commun 285:939-944
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 939-944
    • Corbeil, D.1    Fargeas, C.A.2    Huttner, W.B.3
  • 53
    • 78650970554 scopus 로고    scopus 로고
    • CD133 suppresses neuroblastoma cell differentiation via signal pathway modification
    • Takenobu H, Shimozato O, Nakamura T et al (2011) CD133 suppresses neuroblastoma cell differentiation via signal pathway modification. Oncogene 30:97-105
    • (2011) Oncogene , vol.30 , pp. 97-105
    • Takenobu, H.1    Shimozato, O.2    Nakamura, T.3
  • 54
    • 58849117217 scopus 로고    scopus 로고
    • Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus
    • Mahller YY, Williams JP, Baird WH et al (2009) Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus. PLoS ONE 4:e4235
    • (2009) PLoS ONE , vol.4
    • Mahller, Y.Y.1    Williams, J.P.2    Baird, W.H.3
  • 55
    • 12144291514 scopus 로고    scopus 로고
    • Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133
    • Shmelkov SV, Jun L, St Clair R et al (2004) Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133. Blood 103:2055-2061
    • (2004) Blood , vol.103 , pp. 2055-2061
    • Shmelkov, S.V.1    Jun, L.2    St Clair, R.3
  • 56
    • 78149309989 scopus 로고    scopus 로고
    • Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines
    • Schiapparelli P, Enguita-Germán M, Balbuena J et al (2010) Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines. Oncol Rep 24:1355-1362
    • (2010) Oncol Rep , vol.24 , pp. 1355-1362
    • Schiapparelli, P.1    Enguita-Germán, M.2    Balbuena, J.3
  • 57
    • 58249095085 scopus 로고    scopus 로고
    • Epigenetic regulation of CD133 and tumorigenicity of CD133? ovarian cancer cells
    • Baba T, Convery PA, Matsumura N et al (2009) Epigenetic regulation of CD133 and tumorigenicity of CD133? ovarian cancer cells. Oncogene 28:209-218
    • (2009) Oncogene , vol.28 , pp. 209-218
    • Baba, T.1    Convery, P.A.2    Matsumura, N.3
  • 58
    • 54249127417 scopus 로고    scopus 로고
    • Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors
    • Yi JM, Tsai HC, Glöckner SC et al (2008) Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res 68:8094-8103
    • (2008) Cancer Res , vol.68 , pp. 8094-8103
    • Yi, J.M.1    Tsai, H.C.2    Glöckner, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.