Hantupeptin A, a cytotoxic cyclic depsipeptide from a Singapore collection of Lyngbya majuscula

Journal of Natural Products

Volumn 72, Issue 1, 2009, Pages 29-32

  Tripathi, Ashootosh ^a   Puddick, Jonathan ^b   Prinsep, Michele R ^b   Lee, Peter Peng Foo ^a   Lik, Tong Tan ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b UNIVERSITY OF WAIKATO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

DEPSIPEPTIDE; HANTUPEPTIN A; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CHIRALITY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; LEUKEMIA CELL; LYNGBYA MAJUSCULA; METHANOLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; ANIMAL; ARTEMIA; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; CYANOBACTERIUM; DRUG EFFECT; DRUG SCREENING; FEMALE; HUMAN; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE; POLLINATION; SINGAPORE;

LYNGBYA MAJUSCULA;

ANIMALS; ANTINEOPLASTIC AGENTS; ARTEMIA; CYANOBACTERIA; DEPSIPEPTIDES; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MARINE BIOLOGY; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLLINATION; SINGAPORE;

EID: 60549092554     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np800448t     Document Type: Article

References (21)

1. Tan, L. T. Phytochemistry 2007, 68, 954-979.
2. Gerwick, W. H.; Tan, L. T.; Sitachitta, N. In The Alkaloids; Cordell, G. A., Ed.; Academic Press: San Diego, 2001; Vol. 57, pp 75-184.
3. Ramaswamy, A. V.; Flatt, P. M.; Edwards, D. J.; Simmons, T. L.; Han, B.; Gerwick, W. H. In Frontiers in Marine Biotechnology; Proksch, P., Muller, W. E. G., Eds.; Horizon Bioscience, 2006; pp 175-224.
4. (a) Harrigan, G. G.; Yoshida, W. Y.; Moore, R. E.; Nagle, D. G.; Park, P. U.; Biggs, J.; Paul, V. J.; Mooberry, S. L.; Corbett, T. H.; Valeriote, F. A. J. Nat. Prod. 1998, 61, 1221-1225.
5. (b) Luesch, H.; Yoshida, W. Y.; Moore, R. E.; Paul, V. J. J. Nat. Prod. 1999, 62, 1702-1706.
6. (a) Luesch, H.; Yoshida, W. Y.; Moore, R. E.; Paul, V. J.; Mooberry, S. L. J. Nat. Prod. 2000, 63, 611-615.
7. (b) Milligan, K. E.; Marquez, B. L.; Williamson, R. T.; Gerwick, W. H. J. Nat. Prod. 2000, 63, 1440-1443.
8. (c) Luesch, H.; Yoshida, W. Y.; Moore, R. E.; Paul, V. J. J. Nat. Prod. 2000, 63, 1437-1439.
9. Jaspars, M.; Linda, A. L. Curr. Opp. Drug Discovery Dev. 1998, 1, 77-84.
10. (a) Medina, R. A.; Goeger, D. E.; Hills, P.; Mooberry, S. L.; Huang, N.; Romero, L. I.; Ortega-Barria, E.; Gerwick, W. H.; McPhail, K. L. J. Am. Chem. Soc. 2008, 20, 6324-6325.
11. (b) Taori, K.; Paul, V. J.; Luesch, H. J. Am. Chem. Soc. 2008, 6, 1806-1807.
12. (c) Wrasidlo, W.; Mielgo, A.; Torres, V. A.; Barbero, S.; Stoletov, K.; Suyama, T. L.; Klemke, R. L.; Gerwick, W. H.; Carson, D. A.; Stupack, D. G. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 2313-2318.
13. Tan, L. T.; Chang, Y. Y.; Tripathi, A. Phytochemistry 2008, 69, 2067-2069.
14. Marfey, P. Carlsberg Res. Commun. 1984, 49, 591-596.
15. Fujii, K.; Ikai, Y.; Mayumi, T.; Oka, H.; Suzuki, M.; Harada, K.-I. Anal. Chem. 1997, 69, 3346-3352.
16. Fujii, K.; Ikai, Y.; Oka, H.; Suzuki, M.; Harada, K.-I. Anal. Chem. 1997, 69, 5146-5151.
17. Ohtani, I.; Kusumi, T.; Kashman, Y.; Kakisawa, H. J. Am. Chem. Soc. 1991, 11, 4092-4096.
18. Fernández, R.; Rodrýguez, J.; Quinoá, E.; Riguera, R.; Munoz, L.; Fernández-Suárez, M.; Debitus, C. J. Am. Chem. Soc. 1996, 118, 11635-11643.
19. Nakao, Y.; Yoshida, W. Y.; Szabo, C. M.; Baker, B. J.; Scheuer, P. J. J. Org. Chem. 1998, 63, 3272-3280.
20. Bunyajetpong, S.; Yoshida, W. Y.; Sitachitta, N.; Kaya, K. J. Nat. Prod. 2006, 11, 1539-1542.
21. Smith, J. A.; Pease, L. G. CRC Crit. Rev. Biochem. 1980, 8, 315-399.