Diphenyl diselenide ameliorates behavioral and oxidative parameters in an animal model of mania induced by ouabain

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 38, Issue 2, 2012, Pages 168-174

  Brüning, César Augusto ^a   Prigol, Marina ^a   Luchese, Cristiane ^a   Pinton, Simone ^a   Nogueira, Cristina Wayne ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

Bipolar disorder; Organoselenium; Ouabain; Oxidative stress; Selenium

Indexed keywords

3 NITROTYROSINE; ASCORBIC ACID; CARBONYL DERIVATIVE; CATALASE; DIPHENYL DISELENIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LITHIUM CHLORIDE; OUABAIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; HYPERACTIVITY; LIPID PEROXIDATION; LOCOMOTION; MALE; MANIA; NITRATION; NONHUMAN; OPEN FIELD BEHAVIOR; OXIDATIVE STRESS; RAT;

ANIMALS; BEHAVIOR, ANIMAL; BENZENE DERIVATIVES; BIPOLAR DISORDER; BRAIN; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALE; MOTOR ACTIVITY; ORGANOSELENIUM COMPOUNDS; OUABAIN; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84862872604     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2012.03.005     Document Type: Article

References (67)

1. Aebi H. Catalase in vitro. Methods Enzymol 1984, 105:121-126.
2. Andreazza A.C., Kapczinski F., Kauer-Sant'Anna M., Walz J.C., Bond D.J., Goncalves C.A., Young L.T., Yatham L.N. 3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J Psychiatry Neurosci 2009, 34:263-271.
3. Belmaker R.H. Bipolar disorder. N Engl J Med 2004, 351:476-486.
4. Benton D. Selenium intake, mood and other aspects of psychological functioning. Nutr Neurosci 2002, 5:363-374.
5. Boldyrev A., Bulygina E., Makhro A. Glutamate receptors modulate oxidative stress in neuronal cells. A mini-review. Neurotox Res 2004, 6:581-587.
6. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding. Anal Biochem 1976, 72:248-254.
7. Brocardo P.S., Budni J., Pavesi E., Franco J.L., Uliano-Silva M., Trevisan R., Terenzi M.G., Dafre A.L., Rodrigues A.L.S. Folic acid administration prevents ouabain-induced hyperlocomotion and alterations in oxidative stress markers in the rat brain. Bipolar Disord 2010, 12:414-424.
8. Brüning C.A., Prigol M., Roehrs J.A., Zeni G., Nogueira C.W. Evidence for the involvement of mu-opioid and delta-opioid receptors in the antinociceptive effect caused by oral administration of m-trifluoromethyl-diphenyl diselenide in mice. Behav Pharmacol 2010, 21:621-626.
9. Calberg I., Mannervik B. Glutathione reductase. Methods Enzymol 1985, 113:484-490.
10. De Freitas A.S., Prestes A.S., Wagner C., Sudati J.H., Alves D., Porciúncula L.O., Kade I.J., Rocha J.B.T. Diphenyl diselenide and analogs can be reduced by mammalian thioredoxin reductase independently from their glutathione peroxidase-like activity: a new pathway for their antioxidant activity. Molecules 2010, 15:7699-7714.
11. Dotan Y., Lichtenberg D., Pinchuk I. Lipid peroxidation cannot be used as a universal criterion of oxidative stress. Prog Lipid Res 2004, 43:200-227.
12. Ellman G.L. Tissue sulfhydryl groups. Arch Biochem 1959, 82:70-77.
13. El-Mallakh R.S., Wyatt R.J. The Na, K-ATPase hypothesis for bipolar illness. Biol Psychiatry 1995, 37:235-244.
14. El-Mallakh R.S., Harrison L.T., Li R., Changaris D.G., Levy R.S. An animal model for mania: preliminary results. Prog Neuropsychopharmacol Biol Psychiatry 1995, 19:955-962.
15. El-Mallakh R.S., El-Masri M.A., Huff M.O., Li X.P., Decker S., Levy R.S. Intracerebroventricular administration of ouabain as a model of mania in rats. Bipolar Disord 2003, 5:362-365.
16. El-Mallakh R.S., Decker S., Morris M., Li X.P., Huff M.O., El-Masri M.A., Levy R.S. Efficacy of olanzapine and haloperidol in an animal model of mania. Prog Neuropsychopharmacol Biol Psychiatry 2006, 30(7):1261-1264.
17. Erdal N., Gürgül S., Tamer L., Ayaz L. Effects of long-term exposure of extremely low frequency magnetic field on oxidative/nitrosative stress in rat liver. J Radiat Res 2008, 49:181-187.
18. Floyd R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proc Soc Exp Biol Med 1999, 222:236-245.
19. Frey B.N., Martins M.R., Petronilho F.C., Dal-Pizzol F., Quevedo J., Kapczinski F. Increased oxidative stress after repeated amphetamine exposure: possible relevance as a model of mania. Bipolar Disord 2006, 8:275-280.
20. Frey B.N., Valvassori S.S., Réus G.Z., Martins M.R., Petronilho F.C., Bardini K., Dal-Pizzol F., Kapczinski F., Quevedo J. Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania. J Psychiatry Neurosci 2006, 31:326-332.
21. Frey B.N., Andreazza A.C., Kunz M., Gomes F.A., Quevedo J., Salvador M., Gonçalves C.A., Kapczinski F. Increased oxidative stress and DNA damage in bipolar disorder: a twin-case report. Prog Neuropsychopharmacol Biol Psychiatry 2007, 31:283-285.
22. Ghisleine G., Porciúncula L.O., Cimarosti H., Rocha J.B.T., Salbego C.G., Souza D.O. Diphenyl diselenide protects rat hippocampal slices submitted to oxygen-glucose deprivation and diminishes inducible nitric oxide synthase immunocontent. Brain Res 2003, 986:196-199.
23. Goodwin F.K., Jamison K.R. Manic-depressive illness 1990, Oxford University Press, New York, 36 pp.
24. Haas M., Wang H., Tian J., Xie Z. Src-mediated interceptor cross-talk between the Na/K-ATPase and the EGF receptor relays the signal from ouabain to mitogen-activated protein kinases. J Biol Chem 2002, 277:18694-18702.
25. Hahn C.G., Friedman E. Abnormalities in protein kinase C signaling and the pathophysiology of bipolar disorder. Bipolar Disord 1999, 1:81-86.
26. Herman L., Hougland T., El-Mallakh R.S. Mimicking human bipolar ion dysregulation models mania in rats. Neurosci Biobehav Rev 2007, 31:874-881.
27. Jacques-Silva M.C., Nogueira C.W., Broch L.C., Flores E.M.M., Rocha J.B.T. Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice. Pharmacol Toxicol 2001, 88:119-125.
28. Jornada L.K., Valvassori S.S., Steckert A.V., Moretti M., Mina F., Ferreira C.L., Arent C.O., Dal-Pizzol F., Quevedo J. Lithium and valproate modulate antioxidant enzymes and prevent ouabain-induced oxidative damage in an animal model of mania. J Psychiatry Res 2011, 45:162-168.
29. Kennedy D.J., Vetteth S., Xie M.R., Periyasamy S.M., Xie Z.J., Han C., Basrur V., Mutgi K., Fedorov V., Malhotra D., Shapiro J.I. Ouabain decreases sarco(endo) plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation. Am J Physiol Heart Circ Physiol 2006, 291:3003-3011.
30. Kuloglu M., Ustundag B., Atmaca M., Canatan H., Tezcan E., Cinkilinc N. Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder. Cell Biochem Funct 2002, 20:171-175.
31. Kunz M., Gama C.S., Andreazza A.C., Salvador M., Cereser K.M., Gomes F.A., Belmonte-de-Abreu P.S., Berk M., Kapczinski F. Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2008, 32:1677-1681.
32. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A., Ahn B.W., Shaltiel S., Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990, 186:464-478.
33. Li R., El-Mallakh R.S., Harrison L., Changaris D.G., Levy R.S. Lithium prevents ouabain-induced behavioral changes. Toward an animal model for manic depression. Mol Chem Neuropathol 1997, 31:65-72.
34. Luchese C., Pinton S., Nogueira C.W. Brain and lungs of rats are differently affected by cigarette smoke exposure: antioxidant effect of an organoselenium compound. Pharmacol Res 2009, 59:194-201.
35. Luchese C., Nogueira C.W. Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione S-transferase-like activity dependent on the glutathione content. J Pharm Pharmacol 2010, 62:1146-1151.
36. Machado-Vieira R., Schmidt A.P., Avila T.T., Kapczinski F., Soares J.C., Souza D.O., Portela L.V. Increased cerebrospinal fluid levels of S100B protein in rat model of mania induced by ouabain. Life Sci 2004, 76:805-811.
37. Machado-Vieira R., Andreazza A.C., Viale C.I., Zanatto V., Cereser V., Vargas R., Kapczinski F., Portela L.V., Souza D.O., Salvador M., Gentil V. Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects. Neurosci Lett 2007, 421:33-36.
38. Mahadik S., Evans D., Harbans L. Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2001, 25:463-493.
39. Manji H.K., Chen G. PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Mol Psychiatry 2002, 7:S46-S56.
40. Manji H.K., Lenox R.H. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of bipolar disorder. Biol Psychiatry 1999, 46:1328-1351.
41. Meotti F.C., Stangherlin E.C., Zeni G., Rocha J.B.T., Nogueira C.W. Protective role of aryl and alkyl diselenides on lipid peroxidation. Environ Res 2004, 94:276-282.
42. Misra H.P., Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase. J Biol Chem 1972, 247:3170-3175.
43. Nogueira C.W., Rotta L.N., Perry M.L., Souza D.O., Rocha J.B.T. Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo. Brain Res 2001, 906:157-163.
44. Nonaka S., Hough C.J., Chuang D.M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-d-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci U S A 1998, 95:2642-2647.
45. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
46. Okuma T. Effects of carbamazepine and lithium on affective disorders. Neuropsychobiology 1993, 27:138-145.
47. Ozcan M.E., Gulec M., Ozerol E., Polat R., Akyol O. Antioxidant enzyme activities and oxidative stress in affective disorders. Int Clin Psychopharmacol 2004, 19:89-95.
48. Pasquali L., Busceti C.L., Fulceri F., Paparelli A., Fornai F. Intracellular pathways underlying the effects of lithium. Behav Pharmacol 2010, 21:473-492.
49. Paulmier C. Selenoorganic functional groups. Selenium reagents and intermediates in organic synthesis 1986, 25-51. Pergamon Press, Oxford. first ed. C. Paulmier (Ed.).
50. Price L.H., Heninger G.R. Lithium in the treatment of mood disorders. N Engl J Med 1994, 331:591-598.
51. Prigol M., Brüning C.A., Zeni G., Nogueira C.W. Protective effect of disubstituted diaryl diselenides on cerebral oxidative damage caused by sodium nitroprusside. Biochem Eng J 2009, 45:94-99.
52. Rayman M.P. The importance of selenium to human health. Lancet 2000, 356:233-241.
53. Reznick A.Z., Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 1994, 233:357-363.
54. Riegel R.E., Valvassori S.S., Elias G., Réus G.Z., Steckert A.V., de Souza B., Petronilho F., Gavioli E.C., Dal-Pizzol F., Quevedo J. Animal model of mania induced by ouabain: evidence of oxidative stress in submitochondrial particles of the rat brain. Neurochem Int 2009, 55:491-495.
55. Riegel R.E., Valvassori S.S., Moretti M., Ferreira C.L., Steckert A.V., Souza B., Dal-Pizzol F., Quevedo J. Intracerebroventricular ouabain administration induces oxidative stress in the rat brain. Int J Dev Neurosci 2010, 28:233-237.
56. Rosa R.M., Flores D.G., Appelt H.R., Braga A.L., Henriques J.A.P., Roesler R. Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice. Neurosci Lett 2003, 341:217-220.
57. Rose A.M., Mellett B.J., Valdes R., Kleinman J.E., Herman M.M., Li R., El-Mallakh R.S. Alpha 2 isoform of the Na, K-adenosine triphosphatase is reduced in temporal cortex of bipolar individuals. Biol Psychiatry 1998, 44:892-897.
58. Savas H.A., Gergerlioglu H.S., Armutcu F., Herken H., Yilmaz H.R., Kocoglu E., Selek S., Tutkun H., Zoroglu S.S., Akyol O. Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J Biol Psychiatry 2006, 7:51-55.
59. Savegnago L., Jesse C.R., Pinto L.G., Rocha J.B.T., Nogueira C.W. Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice. Brain Res 2007, 1175:54-59.
60. Savegnago L., Pinto L.G., Jesse C.R., Rocha J.B.T., Nogueira C.W., Zeni G. Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats. Prog Neuropsychopharmacol 2007, 31:1261-1269.
61. Savegnago L., Pinto L.G., Jesse C.R., Barancelli D.A., Rocha J.B.T., Nogueira C.W., Zeni G. Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: involvement of l-arginine-nitric oxide-soluble guanylate cyclase pathway in its antidepressant-like action. Pharmacol Biochem Behav 2008, 88:418-426.
62. Schloesser R.J., Huang J., Klein P.S., Manji H.K. Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology 2008, 33:110-133.
63. Souza A.C.G., Brüning C.A., Leite M.R., Zeni G., Nogueira C.W. Diphenyl diselenide improves scopolamine-induced memory impairment in mice. Behav Pharmacol 2010, 21:556-562.
64. Wendel A. Glutathione peroxidase. Methods Enzymol 1981, 77:325-333.
65. Wilson S.R., Zucker P.A., Huang R.C., Spector A. Development of synthetic compounds with glutathione peroxidase activity. J Am Chem Soc 1989, 111:5936-5939.
66. Young A.H., Newham J.I. Lithium in maintenance therapy for bipolar disorder. J Psychopharmacol 2006, 20:17-22.
67. Xie Z., Kometiani P., Liu J., Li J., Shapiro J.I., Askari A. Intracellular reactive oxygen species mediate the linkage of Na+ / K+-ATPase to hypertrophy and its marker genes in cardiac myocytes. J Biol Chem 1999, 274:19323-19328.