Neuroprotective effect of sesame seed oil in 6-hydroxydopamine induced neurotoxicity in mice model: Cellular, biochemical and neurochemical evidence

Neurochemical Research

Volumn 37, Issue 3, 2012, Pages 516-526

  Ahmad, Saif ^a,b   Khan, M Badruzzaman ^a,b   Hoda, M Nasrul ^a,b   Bhatia, Kanchan ^a,b   Haque, Rizwanul ^a,c   Fazili, Inayat Saleem ^a,d   Jamal, Arshad ^a,e   Khan, Jafar Salamt ^f   Katare, Deepshikha Pande ^a,g  

^a HAMDARD UNIVERSITY   (India)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

^d SHER E KASHMIR UNIVERSITY OF AGRICULTURAL SCIENCES AND TECHNOLOGY OF KASHMIR   (India)

^e KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^f NATIONAL CHEMICAL LABORATORY   (India)

^g AMITY UNIVERSITY   (India)

Author keywords

Antioxidants; NADPH oxidase; Neurotoxicity; Parkinson disease (PD); Sesame seed oil (SO); Tyrosine hydroxylase

Indexed keywords

CATALASE; CYCLOOXYGENASE 2; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MANGANESE SUPEROXIDE DISMUTASE; OXIDOPAMINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SESAME SEED OIL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MOUSE; NEUROCHEMISTRY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBSTANTIA NIGRA; TREATMENT RESPONSE;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; CORPUS STRIATUM; DOPAMINE; ENZYMES; MALE; MICE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; OXIDOPAMINE; SESAME OIL;

MUS; SESAMUM INDICUM;

EID: 84862871811     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0638-4     Document Type: Article

References (55)

1. Andersen JK (2004) Oxidative stress in neurodegeneration: causeor consequence? Nat Med 10:S18-S25 (Pubitemid 38901863)
2. Cui K, Luo X, Xu K, Ven Murthy MR (2004) Role of oxidativestress in neurodegeneration: recent developments in assaymethods for oxidative stress and nutraceutical antioxidants. ProgNeuropsychopharmacol Biol Psychiatry 28:771-799 (Pubitemid 39195270)
3. Hara H, Hiramatsu H, Adachi T (2007) Pyrroloquinoline quinoneis a potent neuroprotective nutrient against 6-hydroxydopamineinducedneurotoxicity. Neurochem Res 32:489-495 (Pubitemid 46295148)
4. Chao J, Yu MS, Ho YS et al (2008) Dietary oxyresveratrol preventsparkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free Radic Biol Med 45:1019-1026
5. Gao QG, Chen WF, Xie JX et al (2009) Ginsenoside Rg1 protectsagainst 6- OHDA-induced neurotoxicity in neuroblastoma SK-NSHcells via IGF-I receptor and estrogen receptor pathways.J Neurochem 109:1338-1347
6. Im HI, Nam E, Lee ES et al (2006) Baicalein Protects 6-OHDA -induced neuronal damage by suppressing oxidative stress. KoreanJ Physiol Pharmacol 10:309-315 (Pubitemid 46099689)
7. Ahmad M, Saleem S, Ahmad AS, Yousuf S et al (2005) Ginkgobiloba affords dose-dependent protection against 6-hydroxydopamine-induced parkinsonism in rats:neurobehavioural, neurochemical and immunohistochemical evidences. J Neurochem 93:94-104 (Pubitemid 40463519)
8. Sun AY, Wang Q, Simonyi A et al (2008) Botanical phenolicsand brain health. Neuromol Med 10:259-274
9. Zhao B (2009) Natural antioxidants protect neurons in Alzheimer'sdisease and Parkinson's disease. Neurochem Res 34:630-638
10. Shad KF, Al-Salam S, Hamza AA (2007) Sesame oil as a protectiveagent against doxorubicin induced cardio toxicity in rat. Am J Pharmacol Toxicol 2:159-163
11. Ahmad S, Yousuf S, Ishrat T et al (2005) Effect of dietary sesameoil as antioxidant on brain hippocampus of rat in focal cerebralischemia. Life Sci 79:1921-1928
12. Jeng KC, Hou RC, Wang JC et al (2005) Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression ofp38 mitogen-activated protein kinase and nuclear factor-kappaB. Immunol Lett 97:101-106 (Pubitemid 40038860)
13. Hsu DZ, Liu MY (2002) Sesame oil attenuates multiple organfailure and increases survival rate during endotoxemia in rats. Crit Care Med 30:1859-1862
14. Sankar D, Sambandam G, Ramakrishna Rao M et al (2005)Modulation of blood pressure, lipid profiles and redox status in hypertensive patients taking different edible oils. Clin Chim Acta355:97-104
15. Cheng FC, Jinn TR, Hou RCW (2006) Neuroprotective effects ofsesamin and sesamolin on gerbil brain in cerebral ischemia. Int JBiomed Sci 2:284-288
16. Lahaie-Collins V, Bournival J, Plouffe M et al (2008) Sesaminmodulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergiccells under MPP+-induced oxidative stress. Oxid MedCell Longev 1:54-62
17. Kong X, Yang JR, Guo LQ et al (2009) Sesamin improvesendothelial dysfunction in renovascular hypertensive rats fed witha high-fat, high-sucrose diet. Eur J Pharmacol 620:84-89
18. Jeng KCG, Hou RCW (2005) Sesamin and sesamolin: nature'stherapeutic lignans. Curr Enzym Inhib 1:11-20
19. Hamada N, Fujita Y, Tanaka A et al (2009) Metabolites of sesamin, a major lignan in sesame seeds, induce neuronal differentiationin PC12 cells through activation of ERK1/2 signalingpathway. J Neural Transm 116:841-852
20. Yokota T, Matsuzaki Y, Koyama M et al (2007) Sesamin, alignan of sesame, down-regulates cyclin D1 protein expression in human tumor cells. Cancer Sci 98:1447-1453 (Pubitemid 47241769)
21. Hou RC, Wu CC, Yang CH et al (2004) Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia. Neurosci Lett 367:10-13 (Pubitemid 39078774)
22. Joshi R, Kumar MS, Satyamoorthy K et al (2005) Free radical reactions and antioxidant activities of sesamol: pulse radiolytic and biochemical studies. J Agric Food Chem 53:2696-2703 (Pubitemid 40471753)
23. Fazli IS, Abdin MZ, Jamal A et al (2005) Interactive effect of sulphur and nitrogen on lipid accumulation, acetyl- CoA concentration and acetyl-CoA carboxylase activity in developing seeds of oilseed crops (Brassica campestris L. and Eruca sativa Mill.). Plant Sci 168:29-36 (Pubitemid 39464762)
24. Budowski P, Connor RT, Field ET (1950) Sesameoil: IV. Determination of free and bound sesamol. J Am Oil Chem Soc 27:307-310
25. Jollow DJ, Mitchell JR, Zampaghone N et al (1974) Bromobenzene induced oxide as the hepatotoxic intermediate. Pharmacology 11:161-169
26. Utley HC, Bernhein F, Hochslein P (1967) Effects of sulfhydryl reagent on peroxidation in microsomes. Arch Biochem Biophys 260:521-531
27. Islam F, Zia S, Sayeed I et al (2002) Selenium induced alteration on lipids, lipid peroxidation, and thiol group in circadian rhythm centers of rat. Biol Trace Elem Res 90:1-12
28. Habig WH, Pabst MJ, Jokoby WB (1974) Glutathione-S-transferase: the first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139
29. Mohandas J, Marshall JJ, Duggin GG et al (1984) Differential distribution of glutathione and glutathione related enzymes in rabbit kidneys: possible implication in analgesic neuropathy. Cancer Res 44:5086-5091
30. Carlberg I, Mannervik B (1975) Glutathione reductase levels in rat brain. J Biol Chem 250:5475-5480
31. Caliborne A (1985) Catalase activity. In: Wakd G (ed) CRC hand book of methods for oxygen radical research. CRC Press, Boca Raton, pp 283-284
32. Beauchamp C, Fridovich I (1971) Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Ann Biochem 44:276-287
33. Bradford MM (1976) Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
34. Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97:1634-1658 (Pubitemid 43873658)
35. Cheung YT, Lau WK, Yu MS et al (2009) Effects of all-transretinoicacid on human SH-SY5Y neuroblastoma as in vitromodel in neurotoxicity research. Neurotox 30:127-135
36. Wu JH, Hodgson JM, Clarke MW et al (2009) Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans:in vitro and human studies. Hyperten 54:1151-1158
37. Fridovich I (1995) Superoxide radical and superoxide dismutases. Annu Rev Biochem 64:97-112
38. Boillée S, Cleveland DW (2008) Revisiting oxidative damage inALS: Microglia, Nox, and mutant SOD1. J Clin Invest 118:474-478 (Pubitemid 351206538)
39. Huang J, Philbert MA (1996) Cellular responses of culturedcerebellar astrocytes to ethacrynic acid-induced perturbation ofsubcellular glutathione homeostasis. Brain Res 711:184-192 (Pubitemid 26080241)
40. Cruz-Auguado R, Almaguer-Melian W, Diaz MC (2001)Behavioural and biochemical effects of glutathione depletion inthe rat brain. Brain Res Bull 55:327-333 (Pubitemid 32727891)
41. Baez S, Segura-Aguilar J, Widersten M (1997) Glutathionetransferases catalyse the detoxication of oxidized metabolites (oquinones)of catecholamines and may serve as an antioxidantsystem preventing degenerative cellular processes. Biochem J 324:25-28 (Pubitemid 27229361)
42. Halliwell B, Gutteridge JM, Cross C (1992) Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med 119:598-620
43. Zafar KS, Siddiqui A, Sayeed I et al (2003) Dose-dependentprotective effect of selenium in rat model of Parkinson's disease:neurobehavioral and neurochemical evidences. J Neurochem 84:438-446 (Pubitemid 36182242)
44. Khan MM, Ahmad A, Ishrat T et al (2010) Resveratrol attenuates6- hydroxydopamine-induced oxidative damage and dopaminedepletion in rat model of Parkinson's disease. Brain Res 1328: 139-151
45. Liu T, Jin H, Sun QR et al (2010) The neuroprotective effects oftanshinone IIA on b-amyloid-induced toxicity in rat corticalneurons. Neuropharmacol 59:595-604
46. Brown DI, Griendling KK (2009) Nox proteins in signal transduction. Free Radic Biol Med 47:1239-1253
47. Nakano D, Kurumazuka D, Nagai Y et al (2008) Dietary sesaminsuppresses aortic NADPH oxidase in DOCA salt hypertensiverats. Clin Exp Pharmacol Physiol 35:324-326 (Pubitemid 351257874)
48. Anantharam V, Kaul S, Song C et al (2007) Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosisin mesencephalic dopaminergic neuronal cells. Neurotoxicology 28:988-997 (Pubitemid 47519806)
49. Teismann P, Vila M, Choi DK (2003) COX-2 and neurodegenerationin Parkinson's disease. Ann N Y Acad Sci 991:272-277
50. Cui Y, Hou X, Chen J et al (2010) Sesamin inhibits bacterialformylpeptide- induced inflammatory responses in a murine airpouchmodel and inTHP-1 human monocytes. Nutr J 140: 377-381
51. Utsunomiya T, Chavali SR, Zhong WW et al (2000) Effects ofsesamin- supplemented dietary fat emulsions on the ex vivoproduction of lipopolysaccharide-induced prostanoids and tumornecrosis factor alpha in rats. Am J Clin Nutr 72:804-808 (Pubitemid 30667103)
52. Jin F, Wu Q, Lu YF et al (2008) Neuroprotective effect of resveratrolon 6-OHDA-induced Parkinson's disease in rats. Eur JPharmacol 600:78-82
53. Callio J, Oury TD, Chu CT (2005) Manganese superoxide dismutaseprotects against 6-hydroxydopamine injury in mousebrains. J Biol Chem 280:18536-18542 (Pubitemid 41389104)
54. Wang J, Du XX, Jiang H et al (2009) Curcumin attenuates6-hydroxydopamine- induced cytotoxicity by anti-oxidation andnuclear factor-kappa B modulation in MES23.5 cells. BiochemPharmacol 78:178-183
55. Rathore P, Dohare P, Varma S et al (2008) Curcuma oil: reducesearly accumulation of oxidative product and is anti-apoptogenicin transient focal ischemia in rat brain. Neurochem Res 33:1672-1682