The ribosome modulates the structural dynamics of the conserved GTPase HflX and triggers tight nucleotide binding

Biochimie

Volumn 94, Issue 8, 2012, Pages 1647-1659

  Fischer, Jeffrey J ^a   Coatham, Mackenzie L ^a   Eagle Bear, Shey ^a   Brandon, Harland E ^a   De Laurentiis, Evelina I ^a   Shields, Michael J ^a   Wieden, Hans Joachim ^a  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

GTPase activated state; HflX; Limited trypsinolysis; Nucleotide binding; Ribosome; Stopped flow

Indexed keywords

50 S RIBOSOME PROTEIN; 70 S RIBOSOME PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; HFLX PROTEIN; RIBOSOMAL PROTEIN L1; RIBOSOMAL PROTEIN S1; RIBOSOMAL PROTEIN S2; RIBOSOME PROTEIN; RNA 30S; RNA 50S; RNA 70S; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; ESCHERICHIA COLI; HYDROLYSIS; IN VITRO STUDY; PROTEIN BINDING; RIBOSOME;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GTP-BINDING PROTEINS; GUANINE NUCLEOTIDES; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; KINETICS; PEPTIDE ELONGATION FACTOR G; PROTEIN CONFORMATION; RIBOSOME SUBUNITS, LARGE, BACTERIAL; RIBOSOME SUBUNITS, SMALL, BACTERIAL;

EID: 84862864984     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.04.016     Document Type: Article

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