-
1
-
-
84885790429
-
Use of enzymes in the synthesis of amino acids
-
(ed. Hughes, A. B.) Wiley-VCH
-
Sonke, T., Kaptein, B. & Schoemaker, H. E. Use of enzymes in the synthesis of amino acids, in Amino Acids, Peptides and Proteins in Organic Chemistry Vol. 1 (ed. Hughes, A. B.) 77-117 (Wiley-VCH, 2009).
-
(2009)
Amino Acids, Peptides and Proteins in Organic Chemistry
, vol.1
, pp. 77-117
-
-
Sonke, T.1
Kaptein, B.2
Schoemaker, H.E.3
-
2
-
-
78449259734
-
Biocatalysis-key to sustainable industrial chemistry
-
Wohlgemuth, R. Biocatalysis-key to sustainable industrial chemistry. Curr. Opin. Biotechnol. 21, 713-724 (2010).
-
(2010)
Curr. Opin. Biotechnol.
, vol.21
, pp. 713-724
-
-
Wohlgemuth, R.1
-
3
-
-
16244402638
-
Advances in biocatalytic synthesis of pharmaceutical intermediates
-
Panke, S. & Wubbolts, M. Advances in biocatalytic synthesis of pharmaceutical intermediates. Curr. Opin. Chem. Biol. 9, 188-194 (2005).
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 188-194
-
-
Panke, S.1
Wubbolts, M.2
-
4
-
-
3543087310
-
Trends and innovations in industrial biocatalysis for the production of fine chemicals
-
Panke, S., Held, M. & Wubbolts, M. Trends and innovations in industrial biocatalysis for the production of fine chemicals. Curr. Opin. Biotechnol. 15, 272-279 (2004).
-
(2004)
Curr. Opin. Biotechnol.
, vol.15
, pp. 272-279
-
-
Panke, S.1
Held, M.2
Wubbolts, M.3
-
5
-
-
79953308640
-
Ammonia lyases and aminomutases as biocatalysts for the synthesis of a-amino and β-amino acids
-
Turner, N. J. Ammonia lyases and aminomutases as biocatalysts for the synthesis of a-amino and β-amino acids. Curr. Opin. Chem. Biol. 15, 234-240 (2011).
-
(2011)
Curr. Opin. Chem. Biol.
, vol.15
, pp. 234-240
-
-
Turner, N.J.1
-
6
-
-
0000451695
-
The purification and properties of β-methylaspartase
-
Barker, H. A., Smyth, R. D.,Wilson, R. M. &Weissbach, H. The purification and properties of β-methylaspartase. J. Biol. Chem. 234, 320-328 (1959).
-
(1959)
J. Biol. Chem.
, vol.234
, pp. 320-328
-
-
Barker, H.A.1
Smyth, R.D.2
Wilson, R.M.3
Weissbach, H.4
-
7
-
-
0026469359
-
Sequencing, and expression in escherichia coli of the clostridium tetanomorphum gene encoding β-methylaspartase and characterization of the recombinant protein
-
Goda, S. K., Minton, N. P., Botting, N. P. & Gani, D. Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding β-methylaspartase and characterization of the recombinant protein. Biochemistry 31, 10747-10756 (1992).
-
(1992)
Biochemistry
, vol.31
, pp. 10747-10756
-
-
Goda, S.K.1
Minton, N.P.2
Botting, N.P.3
Gani D. Cloning4
-
8
-
-
70349389004
-
Alteration of the diastereoselectivity of 3-methylaspartate ammonia lyase by using structure-based mutagenesis
-
Raj, H. et al. Alteration of the diastereoselectivity of 3-methylaspartate ammonia lyase by using structure-based mutagenesis. ChemBioChem 10, 2236-2245 (2009).
-
(2009)
ChemBioChem
, vol.10
, pp. 2236-2245
-
-
Raj, H.1
-
9
-
-
0014073069
-
Divalent metal activation of β-methylaspartase. The importance of ionic radius
-
Bright, H. J. Divalent metal activation of β-methylaspartase. The importance of ionic radius. Biochemistry 6, 1191-1203 (1967).
-
(1967)
Biochemistry
, vol.6
, pp. 1191-1203
-
-
Bright, H.J.1
-
10
-
-
0013492509
-
On the mechanism of divalent metal activation of β-methylaspartase
-
Bright, H. J. On the mechanism of divalent metal activation of β-methylaspartase. J. Biol. Chem. 240, 1198-1210 (1965).
-
(1965)
J. Biol. Chem.
, vol.240
, pp. 1198-1210
-
-
Bright, H.J.1
-
11
-
-
0030729079
-
3-Methylaspartate ammonia-lyase as a marker enzyme of the mesaconate pathway for (S)-glutamate fermentation in Enterobacteriaceae
-
Kato, Y. & Asano, Y. 3-Methylaspartate ammonia-lyase as a marker enzyme of the mesaconate pathway for (S)-glutamate fermentation in Enterobacteriaceae. Arch. Microbiol. 168, 457-463 (1997).
-
(1997)
Arch. Microbiol.
, vol.168
, pp. 457-463
-
-
Kato, Y.1
Asano, Y.2
-
12
-
-
0037040988
-
The structure of 3-methylaspartase from clostridium tetanomorphum functions via the common enolase chemical step
-
Asuncion, M., Blankenfeldt, W., Barlow, J. N., Gani, D. & Naismith, J. H. The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. J. Biol. Chem. 277, 8306-8311 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8306-8311
-
-
Asuncion, M.1
Blankenfeldt, W.2
Barlow, J.N.3
Gani, D.4
Naismith, J.H.5
-
13
-
-
0036151237
-
Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase
-
Levy, C. W. et al. Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase. Structure 10, 105-113 (2002).
-
(2002)
Structure
, vol.10
, pp. 105-113
-
-
Levy, C.W.1
-
14
-
-
0013561354
-
The mechanism of the methylaspartate ammonia-lyase reaction: Deuterium exchange
-
Bright, H. J., Ingraham, L. L. & Lundin, R. E. The mechanism of the methylaspartate ammonia-lyase reaction: deuterium exchange. Biochim. Biophys. Acta 81, 576-584 (1964).
-
(1964)
Biochim. Biophys. Acta
, vol.81
, pp. 576-584
-
-
Bright, H.J.1
Ingraham, L.L.2
Lundin, R.E.3
-
15
-
-
0001687226
-
The mechanism of the β-methylaspartase reaction
-
Bright, H. The mechanism of the β-methylaspartase reaction. J. Biol. Chem. 239, 2307-2315 (1964).
-
(1964)
J. Biol. Chem.
, vol.239
, pp. 2307-2315
-
-
Bright, H.1
-
16
-
-
12644303230
-
The enolase superfamily: A general strategy for enzymecatalyzed abstraction of the a-protons of carboxylic acids
-
Babbitt, P. C. et al. The enolase superfamily: a general strategy for enzymecatalyzed abstraction of the a-protons of carboxylic acids. Biochemistry 35, 16489-16501 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 16489-16501
-
-
Babbitt, P.C.1
-
17
-
-
0023608355
-
Enantiospecific synthesis of 3-substituted aspartic acids via enzymic amination of substituted fumaric acids
-
Akhtar, M., Botting, N. P., Cohen, M. A. & Gani, D. Enantiospecific synthesis of 3-substituted aspartic acids via enzymic amination of substituted fumaric acids. Tetrahedron 43, 5899-5908 (1987).
-
(1987)
Tetrahedron
, vol.43
, pp. 5899-5908
-
-
Akhtar, M.1
Botting, N.P.2
Cohen, M.A.3
Gani, D.4
-
18
-
-
0024291672
-
Substrate specificity of the 3-methylaspartate ammonia-lyase reaction: Observation of differential relative reaction rates for substrate-product pairs
-
Botting, N. P., Akhtar, M., Cohen, M. A. & Gani, D. Substrate specificity of the 3-methylaspartate ammonia-lyase reaction: observation of differential relative reaction rates for substrate-product pairs. Biochemistry 27, 2953-2955 (1988).
-
(1988)
Biochemistry
, vol.27
, pp. 2953-2955
-
-
Botting, N.P.1
Akhtar, M.2
Cohen, M.A.3
Gani, D.4
-
19
-
-
0345084878
-
Preparation of n-substituted aspartic acids via enantiospecific conjugate addition of n-nucleophiles to fumaric acids using methylaspartase: Synthetic utility and mechanistic implications
-
Gulzar, M. S., Akhtar, M. & Gani, D. Preparation of N-substituted aspartic acids via enantiospecific conjugate addition of N-nucleophiles to fumaric acids using methylaspartase: synthetic utility and mechanistic implications. J. Chem. Soc. Perkin Trans. 1, 649-656 (1997).
-
(1997)
J. Chem. Soc. Perkin Trans.
, vol.1
, pp. 649-656
-
-
Gulzar, M.S.1
Akhtar, M.2
Gani, D.3
-
21
-
-
22144485602
-
Expanding the range of substrate acceptance of enzymes: Combinatorial active-site saturation test
-
Reetz, M. T., Bocola, M., Carballeira, J. D., Zha, D. & Vogel, A. Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test. Angew. Chem. Int. Ed. 44, 4192-4196 (2005).
-
(2005)
Angew. Chem. Int. Ed.
, vol.44
, pp. 4192-4196
-
-
Reetz, M.T.1
Bocola, M.2
Carballeira, J.D.3
Zha, D.4
Vogel, A.5
-
22
-
-
18144403554
-
Improving enzyme properties: When are closer mutations better?
-
Morley, K. L. & Kazlauskas, R. J. Improving enzyme properties: when are closer mutations better? Trends Biotechnol. 23, 231-237 (2005).
-
(2005)
Trends Biotechnol.
, vol.23
, pp. 231-237
-
-
Morley, K.L.1
Kazlauskas, R.J.2
-
24
-
-
68049106179
-
Directed evolution drives the next generation of biocatalysts
-
Turner, N. J. Directed evolution drives the next generation of biocatalysts. Nature Chem. Biol. 5, 567-573 (2009).
-
(2009)
Nature Chem. Biol.
, vol.5
, pp. 567-573
-
-
Turner, N.J.1
-
25
-
-
1842585550
-
Characterization of novel l-threo-b-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters
-
Shimamoto, K. et al. Characterization of novel L-threo-b- benzyloxyaspartate derivatives, potent blockers of the glutamate transporters. Mol. Pharmacol. 65, 1008-1015 (2004).
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 1008-1015
-
-
Shimamoto, K.1
-
26
-
-
48249112610
-
Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems
-
Shimamoto, K. Glutamate transporter blockers for elucidation of the function of excitatory neurotransmission systems. Chem. Rec. 8, 182-199 (2008).
-
(2008)
Chem. Rec.
, vol.8
, pp. 182-199
-
-
Shimamoto, K.1
-
27
-
-
26944498280
-
The substituted aspartate analogue l-b-threo-benzylaspartate preferentially inhibits the neuronal excitatory amino acid transporter eaat3
-
Esslinger, C. S. et al. The substituted aspartate analogue L-b-threo-benzylaspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3. Neuropharmacology 49, 850-861 (2005).
-
(2005)
Neuropharmacology
, vol.49
, pp. 850-861
-
-
Esslinger, C.S.1
-
28
-
-
23844450692
-
The excitatory amino acid transporters: Pharmacological insights on substrate and inhibitor specificity of the eaat subtypes
-
Bridges, R. J. & Esslinger, C. S. The excitatory amino acid transporters: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes. Pharmacol. Ther. 107, 271-285 (2005).
-
(2005)
Pharmacol. Ther.
, vol.107
, pp. 271-285
-
-
Bridges, R.J.1
Esslinger, C.S.2
-
29
-
-
49149120836
-
Synthesis and preliminary pharmacological evaluation of novel derivatives of l-b-threobenzylaspartate as inhibitors of the neuronal glutamate transporter eaat3
-
Mavencamp, T. L., Rhoderick, J. F., Bridges, R. J. & Esslinger, C. S. Synthesis and preliminary pharmacological evaluation of novel derivatives of L-b-threobenzylaspartate as inhibitors of the neuronal glutamate transporter EAAT3. Bioorg. Med. Chem. 16, 7740-7748 (2008).
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 7740-7748
-
-
Mavencamp, T.L.1
Rhoderick, J.F.2
Bridges, R.J.3
Esslinger, C.S.4
-
30
-
-
0034613643
-
Syntheses of optically pure β-hydroxyaspartate derivatives as glutamate transporter blockers
-
Shimamoto, K. et al. Syntheses of optically pure β-hydroxyaspartate derivatives as glutamate transporter blockers. Bioorg. Med. Chem. Lett. 10, 2407-2410 (2000).
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 2407-2410
-
-
Shimamoto, K.1
-
31
-
-
77953617184
-
Synthesis of orthogonally protected l-threo-b-ethoxyasparagine
-
Spengler, J., Pelay, M., Tulla-Puche, J. & Albericio, F. Synthesis of orthogonally protected L-threo-b-ethoxyasparagine. Amino Acids 39, 161-165 (2010).
-
(2010)
Amino Acids
, vol.39
, pp. 161-165
-
-
Spengler, J.1
Pelay, M.2
Tulla-Puche, J.3
Albericio, F.4
-
32
-
-
0027291987
-
Design of synthetic gene libraries encoding random sequence proteins with desired ensemble characteristics
-
LaBean, T. H. & Kauffman, S. A. Design of synthetic gene libraries encoding random sequence proteins with desired ensemble characteristics. Protein Sci. 2, 1249-1254 (1993).
-
(1993)
Protein Sci.
, vol.2
, pp. 1249-1254
-
-
LaBean, T.H.1
Kauffman, S.A.2
-
33
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
-
Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K. & Pease, L. R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59 (1989).
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
Pullen, J.K.4
Pease, L.R.5
|