Inhibition of poly(ADP-ribose) polymerase inhibits ischemia/reperfusion induced neurodegeneration in retina via suppression of endoplasmic reticulum stress

Biochemical and Biophysical Research Communications

Volumn 423, Issue 2, 2012, Pages 276-281

  Li, Chuanzhou ^a   Wang, Leilei ^a   Kern, Timothy S ^b   Zheng, Ling ^a  

^a WUHAN UNIVERSITY   (China)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ER stress; Ischemia and reperfusion; Neuroprotection; PARP

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; GPI 15427; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; GLIA CELL; HISTOPATHOLOGY; IMMUNOHISTOLOGY; INTRAOCULAR PRESSURE; MALE; MOUSE; NERVE DEGENERATION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; RETINA CAPILLARY; RETINA ISCHEMIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; HEAT-SHOCK PROTEINS; MALE; MICE; MICE, INBRED C57BL; NEURODEGENERATIVE DISEASES; NEUROGLIA; NUCLEIC ACID SYNTHESIS INHIBITORS; ORGANIC CHEMICALS; POLY(ADP-RIBOSE) POLYMERASES; REPERFUSION INJURY; RETINAL DEGENERATION; TRANSCRIPTION FACTOR CHOP;

MUS;

EID: 84862842660     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.109     Document Type: Article

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